The 4'-hydroxyl group of resveratrol is functionally important for direct activation of PPARα (Q28544833)

1

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Rieko Nakata

2

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Kiyoshi Fukuhara

3

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Hiroshi Yamashita

4

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Hideo Kubodera

5

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Hiroyasu Inoue

Creative Commons Attribution 4.0 International

6

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language of work or name

English

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publication date

2015

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published in

PLOS One

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volume

10

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issue

3

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page(s)

e0120865

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copyright license

start time

23 March 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Resveratrol and Its Metabolites Bind to PPARs

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Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases

19 March 2017

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SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1

19 March 2017

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19 March 2017

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Substrate-specific activation of sirtuins by resveratrol

19 March 2017

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Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

19 March 2017

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Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors

19 March 2017

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Molecular recognition of fatty acids by peroxisome proliferator-activated receptors

19 March 2017

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Development and validation of a genetic algorithm for flexible docking

19 March 2017

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Cancer chemopreventive activity of resveratrol, a natural product derived from grapes

19 March 2017

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The nuclear receptor superfamily: the second decade

19 March 2017

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Therapeutic potential of resveratrol: the in vivo evidence

19 March 2017

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15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma

7 April 2017

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A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation

7 April 2017

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The effect of retarded growth upon the length of life span and upon the ultimate body size. 1935

7 April 2017

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Recent advances in the study on resveratrol

7 April 2017

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Vaticanol C, a resveratrol tetramer, activates PPARalpha and PPARbeta/delta in vitro and in vivo

29 September 2017

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Carvacrol, a component of thyme oil, activates PPARalpha and gamma and suppresses COX-2 expression

29 September 2017

1 reference

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Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation.

29 September 2017

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Phosphodiesterases in the central nervous system

29 September 2017

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Resveratrol as an anti-inflammatory and anti-aging agent: mechanisms and clinical implications

29 September 2017

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Mimetics of caloric restriction include agonists of lipid-activated nuclear receptors

29 September 2017

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Binding of a diverse set of ligands to avidin and streptavidin: an accurate quantitative prediction of their relative affinities by a combination of molecular mechanics and continuum solvent models

29 September 2017

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The molecular basis for the inhibition of phosphodiesterase-4D by three natural resveratrol analogs. Isolation, molecular docking, molecular dynamics simulations, binding free energy, and bioassay

29 September 2017

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Brain protection by resveratrol and fenofibrate against stroke requires peroxisome proliferator-activated receptor alpha in mice

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4370454

Resveratrol inhibits cyclooxygenase-2 transcription and activity in phorbol ester-treated human mammary epithelial cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4370454

Feedback control of cyclooxygenase-2 expression through PPARgamma

3 June 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25798826

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Transcriptional and posttranscriptional regulation of cyclooxygenase-2 expression by fluid shear stress in vascular endothelial cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25798826

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Synthesis and protein-tyrosine kinase inhibitory activity of polyhydroxylated stilbene analogues of piceatannol

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25798826

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0120865

1 reference

3183052

ADS bibcode

2015PLoSO..1020865T

0 references

3183052

1 reference

1 reference

1 reference