Growth factor receptor bound protein 2 (Q28560294)

http://www.ebi.ac.uk/interpro/protein/P62994

Growth factor receptor-bound protein 2

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P62994

SH2 domain superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P62994

membrane protein

1 reference

inferred from GOA cell component → membrane

GRB2, N-terminal SH3 domain, protein family

1 reference

GRB2, C-terminal SH3 domain, protein family

1 reference

SH2 domain, protein family

1 reference

SH3 domain, protein family

1 reference

epidermal growth factor receptor binding

1 reference

17 November 2021

1 reference

17 November 2021

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

9 May 2019

Repetitive peroxide exposure reveals pleiotropic mitogen-activated protein kinase signaling mechanisms

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

neurotrophin TRKA receptor binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

7 references

9 May 2019

Shc and CEACAM1 interact to regulate the mitogenic action of insulin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

9 May 2019

DISC1 regulates neurotrophin-induced axon elongation via interaction with Grb2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

9 May 2019

Interaction of protein tyrosine phosphatase (PTP) 1B with its substrates is influenced by two distinct binding domains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

9 May 2019

The regulatory subunit of PDE6 interacts with PACSIN in photoreceptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

9 May 2019

Direct binding of the signaling adapter protein Grb2 to the activation loop tyrosines on the nerve growth factor receptor tyrosine kinase, TrkA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

9 May 2019

Direct binding of the proline-rich region of protein tyrosine phosphatase 1B to the Src homology 3 domain of p130(Cas)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

9 May 2019

Syndapin I and endophilin I bind overlapping proline-rich regions of dynamin I: role in synaptic vesicle endocytosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

1 reference

9 May 2019

Phosphorylation of cbl after stimulation of Nb2 cells with prolactin and its association with phosphatidylinositol 3-kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

IPI

protein kinase binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

protein phosphatase binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

identical protein binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

ephrin receptor binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

Downstream signaling molecules bind to different phosphorylated immunoreceptor tyrosine-based activation motif (ITAM) peptides of the high affinity IgE receptor

phosphoprotein binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

protein-containing complex

1 reference

9 May 2019

Epidermal growth factor-induced phosphatidylinositol 3-kinase activation and DNA synthesis. Identification of Grb2-associated binder 2 as the major mediator in rat hepatocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

1 reference

9 May 2019

Effects of age on elements of insulin-signaling pathway in central nervous system of rats

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

insulin receptor signaling pathway

IPI

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

positive regulation of signal transduction

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

positive regulation of actin filament polymerization

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

receptor internalization

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

signal transduction in response to DNA damage

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

regulation of MAPK cascade

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

anatomical structure formation involved in morphogenesis

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

protein heterooligomerization

1 reference

9 May 2019

Insulin receptor substrate-1/SHP-2 interaction, a phenotype-dependent switching machinery of insulin-like growth factor-I signaling in vascular smooth muscle cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

branching involved in labyrinthine layer morphogenesis

IDA

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

cellular response to ionizing radiation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

positive regulation of reactive oxygen species metabolic process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994

Ras protein signal transduction

1 reference

9 May 2019

Splicing isoforms of rat Ash/Grb2. Isolation and characterization of the cDNA and genomic DNA clones and implications for the physiological roles of the isoforms

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62994