Matrix metallopeptidase 2 (Q28560329)

Fibronectin type II domain superfamily

1 reference

PGBD-like superfamily

1 reference

72kDa type IV collagenase

1 reference

PGBD superfamily

1 reference

Kringle-like fold

1 reference

Metallopeptidase, catalytic domain superfamily

1 reference

membrane protein

1 reference

inferred from GOA cell component → membrane

Peptidase M10A, catalytic domain, protein family

1 reference

Hemopexin-like domain, protein family

1 reference

Peptidase, metallopeptidase family

1 reference

Fibronectin type II domain, protein family

1 reference

Peptidase M10, metallopeptidase family

1 reference

Peptidoglycan binding-like, protein family

1 reference

Peptidase M10A, cysteine switch, zinc binding site, protein family

1 reference

Hemopexin, conserved site, protein family

1 reference

Hemopexin-like repeats, protein family

1 reference

Matrix metalloproteinase-2, -9 and -13 are involved in fibronectin degradation of rat lung granulomatous fibrosis caused by Angiostrongylus cantonensis

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

14 February 2019

Regulation of collagen degradation in the rat myocardium after infarction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

14 February 2019

Ischemia induced peroxynitrite dependent modifications of cardiomyocyte MLC1 increases its degradation by MMP-2 leading to contractile dysfunction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

metallopeptidase activity

3 references

14 February 2019

Matrix metalloproteinase-9 undergoes expression and activation during dendritic remodeling in adult hippocampus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

1 reference

14 February 2019

Cellular uptake of proMMP-2:TIMP-2 complexes by the endocytic receptor megalin/LRP-2.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

3 references

1 January 2018

The role of matrix metalloproteinases 2 and 9 during rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide

http://www.ebi.ac.uk/QuickGO/annotations?protein=P33436&geneProductId=UniProtKB:P33436

1 January 2018

Coordinated elevation of membrane type 1-matrix metalloproteinase and matrix metalloproteinase-2 expression in rat uterus during postpartum involution

http://www.ebi.ac.uk/QuickGO/annotations?protein=P33436&geneProductId=UniProtKB:P33436

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P33436&geneProductId=UniProtKB:P33436

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

ovarian follicle development

IEA

biological process

1 reference

14 February 2019

Basal membrane remodeling during follicle histogenesis in the rat ovary: contribution of proteinases of the MMP and PA families

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

ovulation from ovarian follicle

1 reference

14 February 2019

Membrane type 1-matrix metalloproteinase (MMP)-associated MMP-2 activation increases in the rat ovary in response to an ovulatory dose of human chorionic gonadotropin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

1 reference

14 February 2019

Distinct expression of gelatinase A [matrix metalloproteinase (MMP)-2], collagenase-3 (MMP-13), membrane type MMP 1 (MMP-14), and tissue inhibitor of MMPs type 1 mediated by physiological signals during formation and regression of the rat corpus lut

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

14 February 2019

Terazosin modifies the content of glycosaminoglycans and the activity of matrix metalloproteinase 2 in the rat ventral prostate

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

response to oxidative stress

1 reference

14 February 2019

Matrix metalloproteinases are down-regulated in rat lenses exposed to oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

negative regulation of cell adhesion

1 reference

14 February 2019

Interactions of proteases, protease inhibitors, and the beta1 integrin/laminin gamma3 protein complex in the regulation of ectoplasmic specialization dynamics in the rat testis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

1 reference

14 February 2019

Embryogenesis of the rat heart: the expression of collagenases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

1 reference

14 February 2019

Aortic adaptation to pregnancy: elevated expression of matrix metalloproteinases-2 and -3 in rat gestation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

1 reference

14 February 2019

Dynamic expression of matrix metalloproteinases 2 and 8 in rat cervix

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

response to radiation

1 reference

14 February 2019

Magnetic brain stimulation upregulates adhesion and prevents Eae: MMP-2, ICAM-1, and VCAM-1 in the choroid plexus as a target

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

response to mechanical stimulus

1 reference

14 February 2019

Angiotensin II signals mechanical stretch-induced cardiac matrix metalloproteinase expression via JAK-STAT pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

peripheral nervous system axon regeneration

1 reference

14 February 2019

Characterisation of matrix metalloproteinases and the effects of a broad-spectrum inhibitor (BB-1101) in peripheral nerve regeneration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

1 reference

14 February 2019

Calcaneal tendon regions exhibit different MMP-2 activation after vertical jumping and treadmill running

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

1 reference

14 February 2019

Interleukin-lβ induces migration of rat arterial smooth muscle cells through a mechanism involving increased matrix metalloproteinase-2 activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

positive regulation of cell migration

1 reference

14 February 2019

Fluid shear stress regulates the invasive potential of glioma cells via modulation of migratory activity and matrix metalloproteinase expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

collagen catabolic process

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

14 February 2019

The involvement of oxidants and NF-κB in cytokine-induced MMP-9 synthesis by bone marrow-derived osteoprogenitor cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

response to retinoic acid

IBA

1 reference

14 February 2019

Retinoic acid diminished the expression of lung tissue matrix metalloproteinase-2 and matrix metalloproteinase-9 in hyperoxia-exposed premature rats through regulating mitogen-activated protein kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

1 reference

14 February 2019

Effect of interferon-gamma on transforming growth factor beta/Smad signal pathway and expression of matrix metalloproteinase-2 and tissue inhibitors of matrix metalloproteinase-2 in cultured rat mesangial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

1 reference

14 February 2019

Evidence for the involvement of matrix metalloproteinases in the cardiovascular effects produced by nicotine

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

response to hydrogen peroxide

1 reference

14 February 2019

Hydrogen peroxide-mediated downregulation of matrix metalloprotease-2 in indomethacin-induced acute gastric ulceration is blocked by melatonin and other antioxidants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

positive regulation of apoptotic process

1 reference

14 February 2019

Matrix metalloproteinase-2 contributes to tumor necrosis factor alpha induced apoptosis in cultured rat cardiac myocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

1 reference

14 February 2019

17beta-estradiol modulation of angiotensin II-stimulated response in cardiac fibroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

negative regulation of vasoconstriction

1 reference

14 February 2019

MMP-2 induced vein relaxation via inhibition of [Ca2+]e-dependent mechanisms of venous smooth muscle contraction. Role of RGD peptides

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

1 reference

1 January 2018

Coordinated elevation of membrane type 1-matrix metalloproteinase and matrix metalloproteinase-2 expression in rat uterus during postpartum involution

http://www.ebi.ac.uk/QuickGO/annotations?protein=P33436&geneProductId=UniProtKB:P33436

response to electrical stimulus

1 reference

14 February 2019

Stretching and electrical stimulation regulate the metalloproteinase-2 in rat denervated skeletal muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

Retinoic acid diminished the expression of lung tissue matrix metalloproteinase-2 and matrix metalloproteinase-9 in hyperoxia-exposed premature rats through regulating mitogen-activated protein kinases

response to hyperoxia

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

prostate gland epithelium morphogenesis

1 reference

14 February 2019

MMP-2 regulates rat ventral prostate development in vitro

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

cellular response to cytokine stimulus

1 reference

14 February 2019

The study of ISO induced heart failure rat model

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

cellular response to interleukin-1

cellular response to estradiol stimulus

1 reference

14 February 2019

17beta-Estradiol inhibits matrix metalloproteinase-2 transcription via MAP kinase in fibroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

cellular response to fluid shear stress

1 reference

14 February 2019

Fluid shear stress regulates the invasive potential of glioma cells via modulation of migratory activity and matrix metalloproteinase expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

extracellular matrix organization

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33436

Peptidase M10A, cysteine switch, zinc binding site

IBA

has part(s)

1 reference

Hemopexin-like domain

1 reference

fibronectin type II domain

1 reference

Peptidase M10, metallopeptidase

1 reference

Peptidase, metallopeptidase

1 reference

Peptidase M10A, catalytic domain

1 reference

Peptidoglycan binding-like

1 reference

Hemopexin, conserved site

1 reference

Hemopexin-like repeats

1 reference