FOS like 1, AP-1 transcription factor subunit (Q28560481)

http://www.ebi.ac.uk/interpro/protein/P10158

Basic-leucine zipper domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

RNA polymerase II transcription regulatory region sequence-specific DNA binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

RNA polymerase II cis-regulatory region sequence-specific DNA binding

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

14 February 2019

A functional activating protein 1 (AP-1) site regulates matrix metalloproteinase 2 (MMP-2) transcription by cardiac cells through interactions with JunB-Fra1 and JunB-FosB heterodimers

GOA

curator

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

DNA-binding transcription activator activity, RNA polymerase II-specific

IBA

1 reference

14 February 2019

A functional activating protein 1 (AP-1) site regulates matrix metalloproteinase 2 (MMP-2) transcription by cardiac cells through interactions with JunB-Fra1 and JunB-FosB heterodimers

GOA

curator

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

14 February 2019

A functional activating protein 1 (AP-1) site regulates matrix metalloproteinase 2 (MMP-2) transcription by cardiac cells through interactions with JunB-Fra1 and JunB-FosB heterodimers

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

DNA-binding transcription factor activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

14 February 2019

Localization of transcription factor AP-1 family proteins in ameloblast nuclei of the rat incisor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

14 February 2019

Experience-dependent decrease in synaptically localized Fra-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

1 reference

14 February 2019

Experience-dependent decrease in synaptically localized Fra-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

1 reference

14 February 2019

Experience-dependent decrease in synaptically localized Fra-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

1 reference

14 February 2019

Experience-dependent decrease in synaptically localized Fra-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

intracellular membrane-bounded organelle

1 reference

14 February 2019

Experience-dependent decrease in synaptically localized Fra-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

in utero embryonic development

biological process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

regulation of transcription, DNA-templated

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

regulation of transcription by RNA polymerase II

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

1 reference

14 February 2019

Differential expression of activator protein-1 transcription factors in pregnant rat myometrium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

1 reference

14 February 2019

Learning-dependent activation of Fra-1: involvement of ventral hippocampus and SNc/VTA complex in learning and habit formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

negative regulation of cell population proliferation

1 reference

14 February 2019

Overexpression of the immediate early gene fra-1 inhibits proliferation, induces apoptosis, and reduces tumourigenicity of c6 glioma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

response to mechanical stimulus

IMP

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

1 reference

14 February 2019

Contribution of REM sleep to Fos and FRA expression in the vestibular nuclei of rat leading to vestibular adaptation during the STS-90 Neurolab Mission

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

response to organic cyclic compound

1 reference

14 February 2019

The differential molecular mechanisms underlying proenkephalin mRNA expression induced by forskolin and phorbol-12-myristic-13-acetate in primary cultured astrocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

cellular response to extracellular stimulus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

Differential expression of activator protein-1 transcription factors in pregnant rat myometrium

response to progesterone

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

1 reference

14 February 2019

The regulation of inducible nitric oxide synthase gene expression induced by lipopolysaccharide and tumor necrosis factor-alpha in C6 cells: involvement of AP-1 and NFkappaB

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

response to hydrogen peroxide

1 reference

14 February 2019

H(2)O(2)-induced egr-1, fra-1, and c-jun gene expression is mediated by tyrosine kinase in aortic smooth muscle cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

positive regulation of apoptotic process

1 reference

14 February 2019

Overexpression of the immediate early gene fra-1 inhibits proliferation, induces apoptosis, and reduces tumourigenicity of c6 glioma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

positive regulation of cell cycle

IMP

1 reference

14 February 2019

Fra-1 promotes growth and survival in RAS-transformed thyroid cells by controlling cyclin A transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

positive regulation of transcription by RNA polymerase II

IMP

1 reference

14 February 2019

A functional activating protein 1 (AP-1) site regulates matrix metalloproteinase 2 (MMP-2) transcription by cardiac cells through interactions with JunB-Fra1 and JunB-FosB heterodimers

GOA

curator

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

positive regulation of DNA-binding transcription factor activity

1 reference

14 February 2019

A functional activating protein 1 (AP-1) site regulates matrix metalloproteinase 2 (MMP-2) transcription by cardiac cells through interactions with JunB-Fra1 and JunB-FosB heterodimers

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

response to corticosterone

1 reference

14 February 2019

Time-course of immediate early gene expression in hippocampal subregions of adrenalectomized rats after acute corticosterone challenge

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

1 reference

14 February 2019

Regulation of AP1 (Jun/Fos) factor expression and activation in ovarian granulosa cells. Relation of JunD and Fra2 to terminal differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

placenta blood vessel development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

pri-miRNA transcription by RNA polymerase II

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

positive regulation of DNA-templated transcription, initiation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10158

Basic-leucine zipper domain

has part(s)

1 reference

stated in

InterPro Release 71.0