CD45 ectodomain controls interaction with GEMs and Lck activity for optimal TCR signaling (Q28567160)

GOA release 2020-03-11

author

Oreste Acuto

6

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author name string

Claudine Irles

1

1 reference

31 January 2017

Antony Symons

2

1 reference

31 January 2017

Frédérique Michel

3

1 reference

31 January 2017

Talitha R. Bakker

4

1 reference

31 January 2017

P. Anton van der Merwe

S-acylation of LCK protein tyrosine kinase is essential for its signalling function in T lymphocytes

5

1 reference

31 January 2017

language of work or name

English

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publication date

1 February 2003

1 reference

31 January 2017

1 reference

31 January 2017

4

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31 January 2017

2

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31 January 2017

189–197

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31 January 2017

1 reference

Expression of CD45 alters phosphorylation of the lck-encoded tyrosine protein kinase in murine lymphoma T-cell lines

21 January 2018

1 reference

Positive and negative regulation of Src-family membrane kinases by CD45.

21 January 2018

1 reference

Structures of Src-family tyrosine kinases

21 January 2018

1 reference

Structural basis for activation of human lymphocyte kinase Lck upon tyrosine phosphorylation

21 January 2018

1 reference

Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation

21 January 2018

1 reference

Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases

21 January 2018

1 reference

Release from tonic inhibition of T cell activation through transient displacement of C-terminal Src kinase (Csk) from lipid rafts

21 January 2018

1 reference

Exclusion of CD45 inhibits activity of p56lck associated with glycolipid-enriched membrane domains

21 January 2018

1 reference

Distinct patterns of membrane microdomain partitioning in Th1 and th2 cells.

21 January 2018

1 reference

Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains

21 January 2018

1 reference

Specific interaction of the CD45 protein-tyrosine phosphatase with tyrosine-phosphorylated CD3 zeta chain

21 January 2018

1 reference

The structure and ligand interactions of CD2: implications for T-cell function

21 January 2018

1 reference

CD45: an emerging role as a protein tyrosine phosphatase required for lymphocyte activation and development

21 January 2018

1 reference

Characterization of the interaction between galectin-1 and lymphocyte glycoproteins CD45 and Thy-1

21 January 2018

1 reference

Biochemical association of CD45 with the T cell receptor complex: regulation by CD45 isoform and during T cell activation

21 January 2018

1 reference

Differential association of CD45 isoforms with CD4 and CD8 regulates the actions of specific pools of p56lck tyrosine kinase in T cell antigen receptor signal transduction

21 January 2018

1 reference

Ligand-mediated negative regulation of a chimeric transmembrane receptor tyrosine phosphatase

21 January 2018

1 reference

Dimerization-induced inhibition of receptor protein tyrosine phosphatase function through an inhibitory wedge

21 January 2018

1 reference

Negative regulation of CD45 by differential homodimerization of the alternatively spliced isoforms

21 January 2018

1 reference

Rescue of signaling by a chimeric protein containing the cytoplasmic domain of CD45.

21 January 2018

1 reference

Tyrosine phosphatase CD45 is required for T-cell antigen receptor and CD2-mediated activation of a protein tyrosine kinase and interleukin 2 production

21 January 2018

1 reference

The leukocyte common antigen family

21 January 2018

1 reference

Rapid activation of the T-cell tyrosine protein kinase pp56lck by the CD45 phosphotyrosine phosphatase

21 January 2018

1 reference

Raft membrane domains and immunoreceptor functions

21 January 2018

1 reference

Targeting of CD45 protein tyrosine phosphatase activity to lipid microdomains on the T cell surface inhibits TCR signaling

21 January 2018

1 reference

LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation

21 January 2018

1 reference

Lipid domain structure of the plasma membrane revealed by patching of membrane components

21 January 2018

1 reference

Second cysteine-rich region of epidermal growth factor receptor contains targeting information for caveolae/rafts

21 January 2018

1 reference

N-terminal protein acylation confers localization to cholesterol, sphingolipid-enriched membranes but not to lipid rafts/caveolae

21 January 2018

1 reference

Microdomain-dependent regulation of Lck and Fyn protein-tyrosine kinases in T lymphocyte plasma membranes

21 January 2018

1 reference

Relationship of lipid rafts to transient confinement zones detected by single particle tracking

21 January 2018

1 reference

Dynamic association of CD45 with detergent-insoluble microdomains in T lymphocytes

21 January 2018

1 reference

Lipid rafts mediate biosynthetic transport to the T lymphocyte uropod subdomain and are necessary for uropod integrity and function

21 January 2018

1 reference

The O-glycosylated stalk domain is required for apical sorting of neurotrophin receptors in polarized MDCK cells

21 January 2018

1 reference

O-linked glycans mediate apical sorting of human intestinal sucrase-isomaltase through association with lipid rafts

21 January 2018

1 reference

Both T cell receptor (TcR)-CD3 complex and CD2 increase the tyrosine kinase activity of p56lck. CD2 can mediate TcR-CD3-independent and CD45-dependent activation of p56lck

21 January 2018

1 reference

CD28 affects the earliest signaling events generated by TCR engagement.

21 January 2018

1 reference

Regulation of Lck activity by CD4 and CD28 in the immunological synapse

21 January 2018

1 reference

A family of receptor-linked protein tyrosine phosphatases in humans and Drosophila

21 January 2018

1 reference

An inactivating point mutation in the inhibitory wedge of CD45 causes lymphoproliferation and autoimmunity

21 January 2018

1 reference

Structural study of the O-linked sugar chains of human leukocyte tyrosine phosphatase CD45

21 January 2018

1 reference

Tyrosine phosphatase CD45 is essential for coupling T-cell antigen receptor to the phosphatidyl inositol pathway

21 January 2018

1 reference

The human p50csk tyrosine kinase phosphorylates p56lck at Tyr-505 and down regulates its catalytic activity

21 January 2018

1 reference

7 January 2021

Evidence that the leukocyte-common antigen is required for antigen-induced T lymphocyte proliferation

1 reference

7 January 2021

Regulation of TCR signaling by CD45 lacking transmembrane and extracellular domains

1 reference

7 January 2021

The dimensions of the T lymphocyte glycoprotein leukosialin and identification of linear protein epitopes that can be modified by glycosylation

1 reference

7 January 2021

The EGF receptor: a nexus for trafficking and signaling

1 reference

7 January 2021