Myosin VIIa and sans localization at stereocilia upper tip-link density implicates these Usher syndrome proteins in mechanotransduction (Q28569812)

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6 February 2020

title

Myosin VIIa and sans localization at stereocilia upper tip-link density implicates these Usher syndrome proteins in mechanotransduction (English)

2 references

31 January 2017

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stereocilia tip-link density

6 February 2020

main subject

1 reference

Gene Ontology release 2020-05-02

1 reference

1 reference

1

1 reference

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6 February 2020

author name string

Bechara Kachar

series ordinal

2

2 references

31 January 2017

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language of work or name

English

0 references

publication date

27 June 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21709241%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

6 February 2020

published in

2 references

31 January 2017

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volume

108

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21709241%20AND%20SRC:MED&resulttype=core&format=json

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issue

28

2 references

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page(s)

11476-11481

1 reference

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describes a project that uses

6 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3136276/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Regulation of stereocilia length by myosin XVa and whirlin depends on the actin-regulatory protein Eps8

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The structure of the harmonin/sans complex reveals an unexpected interaction mode of the two Usher syndrome proteins

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A core cochlear phenotype in USH1 mouse mutants implicates fibrous links of the hair bundle in its cohesion, orientation and differential growth

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Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle

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19 March 2017

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Regeneration of broken tip links and restoration of mechanical transduction in hair cells

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A type VII myosin encoded by the mouse deafness gene shaker-1

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Usher type 1G protein sans is a critical component of the tip-link complex, a structure controlling actin polymerization in stereocilia

19 March 2017

1 reference

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Robust mechanosensing and tension generation by myosin VI

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Genetics and pathological mechanisms of Usher syndrome

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MyosinVIIa interacts with Twinfilin-2 at the tips of mechanosensory stereocilia in the inner ear.

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29 September 2017

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Cadherin 23 and protocadherin 15 interact to form tip-link filaments in sensory hair cells

29 September 2017

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29 September 2017

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21 January 2018

1 reference

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27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21709241

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Quantitative colocalization analysis of confocal fluorescence microscopy images

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21709241

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1104161108

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21709241%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

ADS bibcode

2011PNAS..10811476G

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21709241%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

2 references