Scaffolding function of PAK in the PDK1-Akt pathway (Q28570522)

The phosphoinositide 3-kinase pathway

21 January 2018

1 reference

7 January 2021

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1 reference

7 January 2021

Biology of the p21-activated kinases

1 reference

7 January 2021

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

1 reference

7 January 2021

Differential effects of PAK1-activating mutations reveal activity-dependent and -independent effects on cytoskeletal regulation

1 reference

7 January 2021

p21-activated kinase 1 (Pak1) regulates cell motility in mammalian fibroblasts

1 reference

7 January 2021

Akt mediates Rac/Cdc42-regulated cell motility in growth factor-stimulated cells and in invasive PTEN knockout cells

1 reference

7 January 2021

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

1 reference

7 January 2021

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

1 reference

7 January 2021

Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation

1 reference

7 January 2021

Residues in Cdc42 that specify binding to individual CRIB effector proteins

1 reference

7 January 2021

Thrombin activates the p21-activated kinase in pulmonary artery smooth muscle cells. Role in tissue factor expression

1 reference

7 January 2021

Regulation of Akt/PKB activity by P21-activated kinase in cardiomyocytes

1 reference

7 January 2021

Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B

1 reference

7 January 2021

p21-activated kinase (PAK1) is phosphorylated and activated by 3-phosphoinositide-dependent kinase-1 (PDK1).

1 reference

7 January 2021

Analysis of small GTPase signaling pathways using p21-activated kinase mutants that selectively couple to Cdc42.

1 reference

7 January 2021

Stimulation of membrane ruffling and MAP kinase activation by distinct effectors of RAS.

1 reference

7 January 2021

Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade

1 reference

7 January 2021

Distinct roles of Akt1 and Akt2 in regulating cell migration and epithelial-mesenchymal transition

1 reference

7 January 2021

Akt blocks breast cancer cell motility and invasion through the transcription factor NFAT

1 reference

7 January 2021

Opposing Roles for Akt1 and Akt2 in Rac/Pak Signaling and Cell Migration

1 reference

7 January 2021

Advances in protein kinase B signalling: AKTion on multiple fronts

1 reference

7 January 2021

Recent advances in the protein kinase B signaling pathway

1 reference

7 January 2021

Akt Phosphorylation of Serine 21 on Pak1 Modulates Nck Binding and Cell Migration

1 reference

7 January 2021

The phosphatidylinositol-3 kinase (PI3K)-Akt pathway suppresses neurite branch formation in NGF-treated PC12 cells

1 reference

7 January 2021

Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch

1 reference

7 January 2021

Mammalian expression vectors for epitope tag fusion proteins that are toxic in E. coli

1 reference

7 January 2021

The active conformation of the PAK1 kinase domain

1 reference

7 January 2021

Identifiers

DOI

10.1038/NCB1795

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

1278108

1027897871

0 references

1278108

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference