Interaction between autism-linked MDGAs and neuroligins suppresses inhibitory synapse development (Q28571273)

2

1 reference

31 January 2017

Hideto Takahashi

3

1 reference

31 January 2017

Yuan Ge

4

1 reference

31 January 2017

Ann Marie Craig

describes a project that uses

5

1 reference

31 January 2017

language of work or name

English

0 references

publication date

4 February 2013

1 reference

31 January 2017

Journal of Cell Biology

1 reference

31 January 2017

200

1 reference

31 January 2017

321–336

1 reference

31 January 2017

3

1 reference

31 January 2017

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3563690/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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The neurexin ligands, neuroligins and leucine-rich repeat transmembrane proteins, perform convergent and divergent synaptic functions in vivo

19 March 2017

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IL-1 receptor accessory protein-like 1 associated with mental retardation and autism mediates synapse formation by trans-synaptic interaction with protein tyrosine phosphatase δ

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Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function

19 March 2017

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IgSF molecule MDGA1 is involved in radial migration and positioning of a subset of cortical upper-layer neurons

19 March 2017

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EphB-mediated degradation of the RhoA GEF Ephexin5 relieves a developmental brake on excitatory synapse formation

19 March 2017

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Functional impact of global rare copy number variation in autism spectrum disorders

19 March 2017

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LRRTMs and neuroligins bind neurexins with a differential code to cooperate in glutamate synapse development

19 March 2017

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Neuroligin-2 deletion selectively decreases inhibitory synaptic transmission originating from fast-spiking but not from somatostatin-positive interneurons

19 March 2017

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Neuroligin 2 drives postsynaptic assembly at perisomatic inhibitory synapses through gephyrin and collybistin

19 March 2017

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The emerging role of synaptic cell-adhesion pathways in the pathogenesis of autism spectrum disorders

19 March 2017

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Autism genome-wide copy number variation reveals ubiquitin and neuronal genes

19 March 2017

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An unbiased expression screen for synaptogenic proteins identifies the LRRTM protein family as synaptic organizers

19 March 2017

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Neuroligins and neurexins link synaptic function to cognitive disease

19 March 2017

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Synaptic imbalance, stereotypies, and impaired social interactions in mice with altered neuroligin 2 expression

19 March 2017

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Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism

19 March 2017

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Neuroligin-3 is a neuronal adhesion protein at GABAergic and glutamatergic synapses

19 March 2017

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A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice

19 March 2017

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Activity-dependent validation of excitatory versus inhibitory synapses by neuroligin-1 versus neuroligin-2

19 March 2017

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Mapping autism risk loci using genetic linkage and chromosomal rearrangements

19 March 2017

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Genome-wide atlas of gene expression in the adult mouse brain

19 March 2017

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Neuroligins determine synapse maturation and function

19 March 2017

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Radial migration of superficial layer cortical neurons controlled by novel Ig cell adhesion molecule MDGA1

19 March 2017

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Activity-dependent regulation of MEF2 transcription factors suppresses excitatory synapse number

19 March 2017

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Control of excitatory and inhibitory synapse formation by neuroligins

19 March 2017

1 reference

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Neurexins induce differentiation of GABA and glutamate postsynaptic specializations via neuroligins

19 March 2017

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Neuroligin 2 is exclusively localized to inhibitory synapses

19 March 2017

1 reference

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Identification and characterization of two novel brain-derived immunoglobulin superfamily members with a unique structural organization

19 March 2017

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Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis

19 March 2017

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Neurexin mediates the assembly of presynaptic terminals

19 March 2017

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SynCAM, a synaptic adhesion molecule that drives synapse assembly

19 March 2017

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Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons

19 March 2017

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Neuroligin 1 is a postsynaptic cell-adhesion molecule of excitatory synapses

19 March 2017

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Binding of neuroligins to PSD-95

19 March 2017

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Multiple Recurrent De Novo CNVs, Including Duplications of the 7q11.23 Williams Syndrome Region, Are Strongly Associated with Autism

19 March 2017

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Model of autism: increased ratio of excitation/inhibition in key neural systems

23 March 2017

1 reference

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Dendritic spine pathology in neuropsychiatric disorders

7 April 2017

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A splice code for trans-synaptic cell adhesion mediated by binding of neuroligin 1 to alpha- and beta-neurexins

7 April 2017

1 reference

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A synaptic trek to autism

7 April 2017

1 reference

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The role of neurexins and neuroligins in the formation, maturation, and function of vertebrate synapses

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563690

Selective control of inhibitory synapse development by Slitrk3-PTPδ trans-synaptic interaction.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563690

Mutations causing syndromic autism define an axis of synaptic pathophysiology

29 September 2017

1 reference

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The X-linked intellectual disability protein IL1RAPL1 regulates excitatory synapse formation by binding PTPδ and RhoGAP2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563690

Identification and functional characterization of rare mutations of the neuroligin-2 gene (NLGN2) associated with schizophrenia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563690

Neuroligin-4 is localized to glycinergic postsynapses and regulates inhibition in the retina

29 September 2017

1 reference

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Synaptic organizing complexes

29 September 2017

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Severe Progressive Autism Associated with Two de novo Changes: A 2.6-Mb 2q31.1 Deletion and a Balanced t(14;21)(q21.1;p11.2) Translocation with Long-Range Epigenetic Silencing of LRFN5 Expression

29 September 2017

1 reference

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Selected SALM (synaptic adhesion-like molecule) family proteins regulate synapse formation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563690

Genome-wide analyses of exonic copy number variants in a family-based study point to novel autism susceptibility genes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563690

RSY-1 is a local inhibitor of presynaptic assembly in C. elegans

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563690

Mutations in the calcium-related gene IL1RAPL1 are associated with autism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563690

Silencing of neuroligin function by postsynaptic neurexins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563690

Structure function and splice site analysis of the synaptogenic activity of the neurexin-1 beta LNS domain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563690

How to build a central synapse: clues from cell culture

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563690

Neuroligins mediate excitatory and inhibitory synapse formation: involvement of PSD-95 and neurexin-1beta in neuroligin-induced synaptic specificity.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563690

A balance between excitatory and inhibitory synapses is controlled by PSD-95 and neuroligin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563690

Postsynaptic TrkC and presynaptic PTPσ function as a bidirectional excitatory synaptic organizing complex.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563690

Alternative splicing controls selective trans-synaptic interactions of the neuroligin-neurexin complex.

3 June 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201206028

MDGA1, an IgSF molecule containing a MAM domain, heterophilically associates with axon- and muscle-associated binding partners through distinct structural domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201206028

Association analysis of schizophrenia on 18 genes involved in neuronal migration: MDGA1 as a new susceptibility gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201206028

Wnt signaling positions neuromuscular connectivity by inhibiting synapse formation in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201206028

The MDGA1 gene confers risk to schizophrenia and bipolar disorder.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201206028

Mutations in the gene encoding CADM1 are associated with autism spectrum disorder.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201206028

21 January 2018

Identifiers

DOI

10.1083/JCB.201206028

1 reference

2698319

2698319

1 reference

1 reference

1 reference