Reciprocal modulation of I (h) and I (TASK) in thalamocortical relay neurons by halothane (Q28573202)

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7 January 2020

title

Reciprocal modulation of I (h) and I (TASK) in thalamocortical relay neurons by halothane (English)

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7 January 2020

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2

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Matthias Pawlowski

3

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Sven G Meuth

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author name string

Thomas Budde

1

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Patrick Meuth

4

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Tatyana Kanyshkova

5

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Ansgar Japes

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Hans-Christian Pape

8

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publication date

14 May 2008

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7 January 2020

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volume

456

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issue

6

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page(s)

1061-1073

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7 January 2020

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cites work

Properties of a hyperpolarization-activated cation current and its role in rhythmic oscillation in thalamic relay neurones

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Adenosine promotes burst activity in guinea-pig geniculocortical neurones through two different ionic mechanisms

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Convergent and reciprocal modulation of a leak K+ current and I(h) by an inhalational anaesthetic and neurotransmitters in rat brainstem motoneurones

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Mechanism of anesthesia revealed by shunting actions of isoflurane on thalamocortical neurons.

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Halothane depresses action potential conduction in hippocampal axons.

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Molecular characterization of a slowly gating human hyperpolarization-activated channel predominantly expressed in thalamus, heart, and testis

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Heteromeric HCN1-HCN4 channels: a comparison with native pacemaker channels from the rabbit sinoatrial node

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Contribution of TWIK-related acid-sensitive K+ channel 1 (TASK1) and TASK3 channels to the control of activity modes in thalamocortical neurons.

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Inhalational anesthetics activate two-pore-domain background K+ channels

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THIK-1 and THIK-2, a novel subfamily of tandem pore domain K+ channels

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Membrane resting potential of thalamocortical relay neurons is shaped by the interaction among TASK3 and HCN2 channels.

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Halothane effect on cAMP generation and hydrolysis in rat brain.

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Thalamic bursting in rats during different awake behavioral states.

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Which molecular targets are most relevant to general anaesthesia?

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The in vivo contributions of TASK-1-containing channels to the actions of inhalation anesthetics, the alpha(2) adrenergic sedative dexmedetomidine, and cannabinoid agonists.

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Neurotransmitter actions in the thalamus and cerebral cortex and their role in neuromodulation of thalamocortical activity

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TREK-1, a K+ channel involved in neuroprotection and general anesthesia

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Simulation of the currents involved in rhythmic oscillations in thalamic relay neurons

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Synchronized activities of coupled oscillators in the cerebral cortex and thalamus at different levels of vigilance

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Anesthesia and sleep.

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The TASK-1 two-pore domain K+ channel is a molecular substrate for neuronal effects of inhalation anesthetics.

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Cns distribution of members of the two-pore-domain (KCNK) potassium channel family.

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Impaired regulation of thalamic pacemaker channels through an imbalance of subunit expression in absence epilepsy.

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The contribution of TWIK-related acid-sensitive K+-containing channels to the function of dorsal lateral geniculate thalamocortical relay neurons.

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Modulation of TASK-1 (Kcnk3) and TASK-3 (Kcnk9) potassium channels: volatile anesthetics and neurotransmitters share a molecular site of action

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Evidence for direct actions of general anesthetics on an ion channel protein. A new look at a unified mechanism of action.

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Dendritic excitability of mouse frontal cortex pyramidal neurons is shaped by the interaction among HCN, Kir2, and Kleak channels.

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12 December 2020

TASK-3 knockout mice exhibit exaggerated nocturnal activity, impairments in cognitive functions, and reduced sensitivity to inhalation anesthetics.

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Role of subunit heteromerization and N-linked glycosylation in the formation of functional hyperpolarization-activated cyclic nucleotide-gated channels

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10.1007/S00424-008-0482-9

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7 January 2020

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