Synaptotagmin IV is necessary for the maturation of secretory granules in PC12 cells (Q28575290)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16618809%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

Synaptotagmin IV is necessary for the maturation of secretory granules in PC12 cells (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16618809%20AND%20SRC:MED&resulttype=core&format=json

vesicle fusion with vesicle

19 January 2020

main subject

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0061782

secretory granule maturation

1 reference

Gene Ontology release 2020-05-02

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16618809%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Sharon Tooze

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16618809%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

author name string

Malika Ahras

series ordinal

1

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16618809%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

language of work or name

English

0 references

publication date

17 April 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16618809%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

published in

Journal of Cell Biology

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16618809%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

volume

173

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16618809%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

issue

2

2 references

31 January 2017

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19 January 2020

page(s)

241-251

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16618809%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

19 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2063815/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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RNA interference-mediated silencing of synaptotagmin IX, but not synaptotagmin I, inhibits dense-core vesicle exocytosis in PC12 cells

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17 March 2017

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Synaptotagmin IV is present at the Golgi and distal parts of neurites

17 March 2017

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17 March 2017

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17 March 2017

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Binding of the synaptic vesicle v-SNARE, synaptotagmin, to the plasma membrane t-SNARE, SNAP-25, can explain docked vesicles at neurotoxin-treated synapses

17 March 2017

1 reference

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Phospholipid composition dependence of Ca2+-dependent phospholipid binding to the C2A domain of synaptotagmin IV

17 March 2017

1 reference

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A third synaptotagmin gene, Syt3, in the mouse

17 March 2017

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Synaptotagmin IV is an immediate early gene induced by depolarization in PC12 cells and in brain

17 March 2017

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Synaptotagmin VII is targeted to secretory organelles in PC12 cells, where it functions as a high-affinity calcium sensor

17 March 2017

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Kinetic efficiency of endocytosis at mammalian CNS synapses requires synaptotagmin I

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Deficits in memory and motor performance in synaptotagmin IV mutant mice

29 September 2017

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29 September 2017

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29 September 2017

1 reference

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29 September 2017

1 reference

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Mannose 6-phosphate receptors are sorted from immature secretory granules via adaptor protein AP-1, clathrin, and syntaxin 6-positive vesicles

29 September 2017

1 reference

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Interaction of furin in immature secretory granules from neuroendocrine cells with the AP-1 adaptor complex is modulated by casein kinase II phosphorylation

29 September 2017

1 reference

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Differential sorting of lysosomal enzymes out of the regulated secretory pathway in pancreatic beta-cells

29 September 2017

1 reference

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pH-dependent processing of secretogranin II by the endopeptidase PC2 in isolated immature secretory granules.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063815

The AP-1 adaptor complex binds to immature secretory granules from PC12 cells, and is regulated by ADP-ribosylation factor

29 September 2017

1 reference

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Kinetics of the secretory response in bovine chromaffin cells following flash photolysis of caged Ca2+.

29 September 2017

1 reference

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Identification of a synaptic vesicle-specific membrane protein with a wide distribution in neuronal and neurosecretory tissue

29 September 2017

1 reference

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Newly synthesized synaptophysin is transported to synaptic-like microvesicles via constitutive secretory vesicles and the plasma membrane.

29 September 2017

1 reference

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Synaptotagmin IV overexpression inhibits depolarization-induced exocytosis in PC12 cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063815

Comparative analysis of tandem C2 domains from the mammalian synaptotagmin family

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063815

A novel function for the second C2 domain of synaptotagmin. Ca2+-triggered dimerization.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063815

A role for synaptotagmin (p65) in regulated exocytosis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063815

Characterization of the endopeptidase PC2 activity towards secretogranin II in stably transfected PC12 cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063815

Cell-free protein sorting to the regulated and constitutive secretory pathways

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063815

Domain structure of synaptotagmin (p65)

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063815

Characterization of the immature secretory granule, an intermediate in granule biogenesis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063815

Direct and GTP-dependent Interaction of ADP-ribosylation Factor 1 with Clathrin Adaptor Protein AP-1 on Immature Secretory Granules

3 June 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200506163

Calcium-dependent and -independent hetero-oligomerization in the synaptotagmin family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200506163

Effect of forskolin on synaptotagmin IV protein trafficking in PC12 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200506163

Nerve growth factor-dependent sorting of synaptotagmin IV protein to mature dense-core vesicles that undergo calcium-dependent exocytosis in PC12 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200506163

The proteolytic maturation of prohormone convertase 2 (PC2) is a pH-driven process.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200506163

Neuroendocrine secretory protein 7B2: structure, expression and functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200506163

Calcium-dependent oligomerization of synaptotagmins I and II. Synaptotagmins I and II are localized on the same synaptic vesicle and heterodimerize in the presence of calcium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200506163

Inhibition of the vacuolar H+-ATPase perturbs the transport, sorting, processing and release of regulated secretory proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200506163

Biogenesis of secretory granules in the trans-Golgi network of neuroendocrine and endocrine cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200506163

The C2B domain of synaptotagmin I is a Ca2+-binding module.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200506163

Synaptotagmin modulation of fusion pore kinetics in regulated exocytosis of dense-core vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200506163

Different domains of synaptotagmin control the choice between kiss-and-run and full fusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200506163

Mechanisms of pH regulation in the regulated secretory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200506163

SNAP-25 and Synaptotagmin 1 Function in Ca2+-Dependent Reversible Docking of Granules to the Plasma Membrane

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16618809

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Proteolytic maturation of insulin is a post-Golgi event which occurs in acidifying clathrin-coated secretory vesicles

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16618809

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1083/JCB.200506163

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16618809%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16618809%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

2 references