The loss of glypican-3 induces alterations in Wnt signaling (Q28575434)

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31 January 2017

Wen Shi

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31 January 2017

Yun-Yan Xiang

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31 January 2017

Jorge Filmus

Journal of Biological Chemistry

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31 January 2017

language of work or name

English

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publication date

21 January 2005

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31 January 2017

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31 January 2017

280

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31 January 2017

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31 January 2017

2116–2125

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31 January 2017

Molecular cloning of a phosphatidylinositol-anchored membrane heparan sulfate proteoglycan from human lung fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Glypicans: proteoglycans with a surprise

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Heparan Sulfate Core Proteins in Cell-Cell Signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Characterization of glypican-5 and chromosomal localization of human GPC5, a new member of the glypican gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Glypican-6, a new member of the glypican family of cell surface heparan sulfate proteoglycans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

The role of glypicans in mammalian development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Functions of cell surface heparan sulfate proteoglycans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Heparan sulfate fine structure and specificity of proteoglycan functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Functional binding of secreted molecules to heparan sulfate proteoglycans in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Specificities of heparan sulphate proteoglycans in developmental processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

glypican-3 controls cellular responses to Bmp4 in limb patterning and skeletal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Identification of Hedgehog pathway components by RNAi in Drosophila cultured cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

The glypican Dally-like is required for Hedgehog signalling in the embryonic epidermis of Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

The zebrafish glypican knypek controls cell polarity during gastrulation movements of convergent extension

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Role of glypican 4 in the regulation of convergent extension movements during gastrulation in Xenopus laevis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Processing by proprotein convertases is required for glypican-3 modulation of cell survival, Wnt signaling, and gastrulation movements

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Dally regulates Dpp morphogen gradient formation in the Drosophila wing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Drosophila glypicans control the cell-to-cell movement of Hedgehog by a dynamin-independent process.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Opposing activities of Dally-like glypican at high and low levels of Wingless morphogen activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Spatial regulation of Wingless morphogen distribution and signaling by Dally-like protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Glypican-3-deficient mice exhibit developmental overgrowth and some of the abnormalities typical of Simpson-Golabi-Behmel syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Role of insulin-like growth factors in embryonic and postnatal growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

OCI-5/rat glypican-3 binds to fibroblast growth factor-2 but not to insulin-like growth factor-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Overgrowth of a mouse model of the Simpson-Golabi-Behmel syndrome is independent of IGF signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

The IRS-signalling system during insulin and cytokine action

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

OCI-5/GPC3, a glypican encoded by a gene that is mutated in the Simpson-Golabi-Behmel overgrowth syndrome, induces apoptosis in a cell line-specific manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Protein kinase B alpha/Akt1 regulates placental development and fetal growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Akt/protein kinase B promotes organ growth in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Mice lacking cyclin D1 are small and show defects in eye and mammary gland development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

The cell-surface proteoglycan Dally regulates Wingless signalling in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Antagonistic regulation of convergent extension movements in Xenopus by Wnt/beta-catenin and Wnt/Ca2+ signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Cell autonomous regulation of multiple Dishevelled-dependent pathways by mammalian Nkd

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

The TAK1-NLK mitogen-activated protein kinase cascade functions in the Wnt-5a/Ca(2+) pathway to antagonize Wnt/beta-catenin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent beta-catenin degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Wnt-5/pipetail functions in vertebrate axis formation as a negative regulator of Wnt/beta-catenin activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Multiple mechanisms for Wnt11-mediated repression of the canonical Wnt signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Ca(2+)/calmodulin-dependent protein kinase II is stimulated by Wnt and Frizzled homologs and promotes ventral cell fates in Xenopus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Increasingly complex: new players enter the Wnt signaling network

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

JNK functions in the non-canonical Wnt pathway to regulate convergent extension movements in vertebrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Expression of GPC3, an X-linked recessive overgrowth gene, is silenced in malignant mesothelioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

When Wnts antagonize Wnts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

QSulf1 remodels the 6-O sulfation states of cell surface heparan sulfate proteoglycans to promote Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Genetic control of cell size

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Expression patterns of Wnts, Frizzleds, sFRPs, and misexpression in transgenic mice suggesting a role for Wnts in pancreas and foregut pattern formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

Glypicans: a growing trend

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200

The DIX domain targets dishevelled to actin stress fibres and vesicular membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410090200