Small molecule AKAP-protein kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytes (Q28578129)

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English	Small molecule AKAP-protein kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytes	scientific journal article

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scholarly article

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PubMed publication ID

31 January 2017

Small molecule AKAP-protein kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytes (English)

1 reference

PubMed publication ID

31 January 2017

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Frank Christian

object named as

Frank Christian

1

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Friedrich W. Herberg

object named as

Friedrich W. Herberg

28

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Bernd Reif

15

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Hans-Gottfried Genieser

object named as

Hans-Gottfried Genieser

27

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Miles D. Houslay

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Miles D. Houslay

32

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author name string

Márta Szaszák

2

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31 January 2017

Sabine Friedl

3

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31 January 2017

Stephan Drewianka

4

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31 January 2017

Dorothea Lorenz

5

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31 January 2017

Andrey Goncalves

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Jens Furkert

7

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Carolyn Vargas

8

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Peter Schmieder

9

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Frank Götz

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Kerstin Zühlke

11

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Marie Moutty

12

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Hendrikje Göttert

13

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31 January 2017

Mangesh Joshi

14

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Hannelore Haase

16

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Ingo Morano

17

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Solveig Grossmann

18

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Anna Klukovits

19

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Judit Verli

20

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Róbert Gáspár

21

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Claudia Noack

22

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31 January 2017

Martin Bergmann

23

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Robert Kass

24

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Kornelia Hampel

25

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31 January 2017

Dmitry Kashin

26

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31 January 2017

Debbie Willoughby

29

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31 January 2017

Dermot M. F. Cooper

30

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31 January 2017

George S. Baillie

31

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31 January 2017

Jens Peter von Kries

33

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31 January 2017

Bastian Zimmermann

34

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31 January 2017

Walter Rosenthal

35

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31 January 2017

Enno Klussmann

36

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31 January 2017

language of work or name

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publication date

18 March 2011

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31 January 2017

Journal of Biological Chemistry

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31 January 2017

286

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31 January 2017

11

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31 January 2017

9079–9096

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31 January 2017

Structure of D-AKAP2:PKA RI Complex: Insights into AKAP Specificity and Selectivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058960

17 March 2017

The A-kinase anchoring protein Yotiao binds and regulates adenylyl cyclase in brain

1 reference

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17 March 2017

AKAP complex regulates Ca2+ re-uptake into heart sarcoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058960

17 March 2017

A dynamic mechanism for AKAP binding to RII isoforms of cAMP-dependent protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058960

17 March 2017

Dynamic regulation of cAMP synthesis through anchored PKA-adenylyl cyclase V/VI complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058960

17 March 2017

An anchored PKA and PDE4 complex regulates subplasmalemmal cAMP dynamics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058960

17 March 2017

Phosphorylation of the A-kinase-anchoring protein Yotiao contributes to protein kinase A regulation of a heart potassium channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058960

17 March 2017

Identification of a novel A-kinase anchoring protein 18 isoform and evidence for its role in the vasopressin-induced aquaporin-2 shuttle in renal principal cells

1 reference

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Functional characterization of the human atrial essential myosin light chain (hALC-1) in a transgenic rat model

1 reference

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17 March 2017

Beta-adrenergic regulation requires direct anchoring of PKA to cardiac CaV1.2 channels via a leucine zipper interaction with A kinase-anchoring protein 15

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058960

17 March 2017

Bioinformatic design of A-kinase anchoring protein-in silico: a potent and selective peptide antagonist of type II protein kinase A anchoring

1 reference

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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

1 reference

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17 March 2017

AKAP-mediated targeting of protein kinase a regulates contractility in cardiac myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058960

17 March 2017

Analysis of A-kinase anchoring protein (AKAP) interaction with protein kinase A (PKA) regulatory subunits: PKA isoform specificity in AKAP binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058960

17 March 2017

A role for AKAP (A kinase anchoring protein) scaffolding in the loss of a cyclic adenosine 3',5'-monophosphate inhibitory response in late pregnant rat myometrium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058960

17 March 2017

Protein kinase A anchoring to the myometrial plasma membrane is required for cyclic adenosine 3',5'-monophosphate regulation of phosphatidylinositide turnover

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058960

17 March 2017

The molecular basis for protein kinase A anchoring revealed by solution NMR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058960

17 March 2017

Identification of a novel protein kinase A anchoring protein that binds both type I and type II regulatory subunits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058960

17 March 2017

Phosphorylation and activation of a cAMP-specific phosphodiesterase by the cAMP-dependent protein kinase. Involvement of serine 54 in the enzyme activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058960

17 March 2017

Association of the type II cAMP-dependent protein kinase with a human thyroid RII-anchoring protein. Cloning and characterization of the RII-binding domain

1 reference

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17 March 2017

Reaching for high-hanging fruit in drug discovery at protein-protein interfaces

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7 April 2017

Cardiac troponin T, a sarcomeric AKAP, tethers protein kinase A at the myofilaments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058960

29 September 2017

Small-molecule protein-protein interaction inhibitors: therapeutic potential in light of molecular size, chemical space, and ligand binding efficiency considerations.

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29 September 2017

Mechanisms of protein kinase A anchoring

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058960

29 September 2017

Disruption of protein kinase A localization using a trans-activator of transcription (TAT)-conjugated A-kinase-anchoring peptide reduces cardiac function

1 reference

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29 September 2017

Glycogen synthase kinase 3beta interaction protein functions as an A-kinase anchoring protein

1 reference

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29 September 2017

Adenylyl cyclase--A-kinase anchoring protein complexes: the next dimension in cAMP signaling

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29 September 2017

AKAP-scaffolding proteins and regulation of cardiac physiology.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058960

29 September 2017

Capturing adenylyl cyclases as potential drug targets

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A-kinase anchoring proteins: from protein complexes to physiology and disease

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Beta-adrenergic stimulation and myocardial function in the failing heart

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29 September 2017

Direct AKAP-mediated protein-protein interactions as potential drug targets

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PDE4 associates with different scaffolding proteins: modulating interactions as treatment for certain diseases.

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The unique functions of cardiac troponin I in the control of cardiac muscle contraction and relaxation

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Signaling through cAMP and cAMP-dependent protein kinase: diverse strategies for drug design.

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Effects of PKA phosphorylation of cardiac troponin I and strong crossbridge on conformational transitions of the N-domain of cardiac troponin C in regulated thin filaments

1 reference

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Organization and Ca2+ regulation of adenylyl cyclases in cAMP microdomains

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Phosphodiesterases and compartmentalized cAMP signalling in the heart

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Protein kinase A type I and type II define distinct intracellular signaling compartments.

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Dilated cardiomyopathy and sudden death resulting from constitutive activation of protein kinase a.

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Selective activation of particulate cAMP-dependent protein kinase by isoproterenol and prostaglandin E1

1 reference

https://pubmed.ncbi.nlm.nih.gov/21177871

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

G protein signalling pathways in myometrium: affecting the balance between contraction and relaxation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21177871

12 December 2020

based on heuristic

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Protein kinase A anchoring proteins are required for vasopressin-mediated translocation of aquaporin-2 into cell membranes of renal principal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21177871

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular basis of AKAP specificity for PKA regulatory subunits

1 reference

https://pubmed.ncbi.nlm.nih.gov/21177871

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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