Characterization and channel coupling of the P2Y(12) nucleotide receptor of brain capillary endothelial cells (Q28578957)

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12080041%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

title

Characterization and channel coupling of the P2Y(12) nucleotide receptor of brain capillary endothelial cells (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12080041%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

0 references

0 references

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12080041%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

author name string

Joseph Simon

1

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12080041%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Sara Göransson

3

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12080041%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Christian Frelin

5

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12080041%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Alexander K Filippov

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12080041%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Anton D Michel

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12080041%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

David A Brown

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12080041%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Eric A Barnard

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12080041%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

language of work or name

English

0 references

publication date

21 June 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12080041%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

10 November 2019

published in

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12080041%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

volume

277

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12080041%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

issue

35

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12080041%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

page(s)

31390-31400

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12080041%20AND%20SRC:MED&resulttype=core&format=json

ATP, a partial agonist of atypical P2y purinoceptors in rat brain microvascular endothelial cells

10 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

The P2Y purinoceptor in rat brain microvascular endothelial cells couple to inhibition of adenylate cyclase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

Activity of adenosine diphosphates and triphosphates on a P2Y(T) -type receptor in brain capillary endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

FPL 66096: a novel, highly potent and selective antagonist at human platelet P2T-purinoceptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

Molecular basis for ADP-induced platelet activation. II. The P2Y1 receptor mediates ADP-induced intracellular calcium mobilization and shape change in platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

Identification of the platelet ADP receptor targeted by antithrombotic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

ADP is the cognate ligand for the orphan G protein-coupled receptor SP1999

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

An elusive receptor is finally caught: P2Y(12'), an important drug target in platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

P2y(12), a new platelet ADP receptor, target of clopidogrel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

Receptors for ADP on human blood platelets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

Competitive inhibition by adenosine 5'-triphosphate of the actions on human platelets of 2-chloroadenosine 5'-diphosphate, 2-azidoadenosine 5'-diphosphate and 2-methylthioadenosine 5'-diphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

Differential effects of adenine nucleotide analogues on shape change and aggregation induced by adnosine 5-diphosphate (ADP) in human platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

Activation of adenylate cyclase by human recombinant sst5 receptors expressed in CHO-K1 cells and involvement of Galphas proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

The P2Y(1) receptor closes the N-type Ca(2+) channel in neurones, with both adenosine triphosphates and diphosphates as potent agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

Multiple pertussis toxin-sensitive G-proteins can couple receptors to GIRK channels in rat sympathetic neurons when expressed heterologously, but only native G(i)-proteins do so in situ

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

Dual coupling of heterologously-expressed rat P2Y6 nucleotide receptors to N-type Ca2+ and M-type K+ currents in rat sympathetic neurones

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

Recombinant P2Y receptors: the UCL experience

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

Gz-mediated hormonal inhibition of cyclic AMP accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

Inhibition of potassium and calcium currents in neurones by molecularly-defined P2Y receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

G protein beta gamma subunits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

Differential G protein-mediated coupling of D2 dopamine receptors to K+ and Ca2+ currents in rat anterior pituitary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

Regulation of GIRK channel deactivation by Galpha(q) and Galpha(i/o) pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

Mechanisms of modulation of voltage-dependent calcium channels by G proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

betagamma dimers derived from Go and Gi proteins contribute different components of adrenergic inhibition of Ca2+ channels in rat sympathetic neurones

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

Role of P2Y1 purinoceptor in ADP-induced platelet activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

Efficacy in drug receptor theory: outdated concept or under-valued tool?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

Effects of varying the expression level of recombinant human mGlu1alpha receptors on the pharmacological properties of agonists and antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

Molecular basis for ADP-induced platelet activation. I. Evidence for three distinct ADP receptors on human platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

Partial agonists, full agonists, antagonists: dilemmas of definition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

Adenosine nucleotides acting at the human P2Y1 receptor stimulate mitogen-activated protein kinases and induce apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

Defective platelet aggregation and increased resistance to thrombosis in purinergic P2Y(1) receptor-null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

ADP and, indirectly, ATP are potent inhibitors of cAMP production in intact isoproterenol-stimulated C6 glioma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

The C6-2B glioma cell P2Y(AC) receptor is pharmacologically and molecularly identical to the platelet P2Y(12) receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

Regulation of cyclic AMP by extracellular ATP in cultured brain capillary endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

The C terminus of the metabotropic glutamate receptor subtypes 2 and 7 specifies the receptor signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

Activation and inhibition of G protein-coupled inwardly rectifying potassium (Kir3) channels by G protein beta gamma subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

Effect of G protein heterotrimer composition on coupling of neurotransmitter receptors to N-type Ca(2+) channel modulation in sympathetic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

P2Y(AC)(-)-receptor agonists enhance the proliferation of rat C6 glioma cells through activation of the p42/44 mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110714200

21 January 2018

Identifiers

DOI

10.1074/JBC.M110714200

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12080041%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

2 references

31 January 2017