TNF-alpha-mediated apoptosis in vascular smooth muscle cells requires p73 (Q28579894)

31 January 2017

title

TNF-alpha-mediated apoptosis in vascular smooth muscle cells requires p73 (English)

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31 January 2017

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Vincent Tang

1

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31 January 2017

Amy Dhirapong

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2

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31 January 2017

Annoel P. Yabes

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3

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31 January 2017

Robert H. Weiss

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4

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31 January 2017

publication date

1 July 2005

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American Journal of Physiology - Cell Physiology

31 January 2017

published in

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31 January 2017

volume

289

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31 January 2017

issue

1

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31 January 2017

page(s)

C199–206

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Detection and localization of tumor necrosis factor in human atheroma

31 January 2017

cites work

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Tumor necrosis factor alpha-induced apoptosis requires p73 and c-ABL activation downstream of RB degradation

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TNF-R1 signaling: a beautiful pathway

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Direct binding of apoptosis signal-regulating kinase 1 to retinoblastoma protein: novel links between apoptotic signaling and cell cycle machinery

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Overexpression of p73 causes apoptosis in vascular smooth muscle cells

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Two new p73 splice variants, gamma and delta, with different transcriptional activity.

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Comparison of vascular smooth muscle cell apoptosis and fibrous cap morphology in symptomatic and asymptomatic carotid artery disease.

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Progression of atheroma: a struggle between death and procreation

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p73 is a simian [correction of human] p53-related protein that can induce apoptosis

21 January 2018

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Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers

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p53 induces the expression of its antagonist p73 Delta N, establishing an autoregulatory feedback loop

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Enhancement of TNF-alpha-mediated cell death in vascular smooth muscle cells through cytochrome c-independent pathway by the proteasome inhibitor

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DeltaNp73beta is active in transactivation and growth suppression.

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21 January 2018

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Autoinhibitory regulation of p73 by Delta Np73 to modulate cell survival and death through a p73-specific target element within the Delta Np73 promoter

21 January 2018

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Increased rate of apoptosis in intimal arterial smooth muscle cells through endogenous activation of TNF receptors

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An anti-apoptotic role for the p53 family member, p73, during developmental neuron death

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Atherosclerosis is an inflammatory disease

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DeltaNp73 stabilises TAp73 proteins but compromises their function due to inhibitory hetero-oligomer formation

21 January 2018

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21 January 2018

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p73 is a growth-regulated protein in vascular smooth muscle cells and is present at high levels in human atherosclerotic plaque

21 January 2018

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p21(Waf1/Cip1) is an assembly factor required for platelet-derived growth factor-induced vascular smooth muscle cell proliferation

21 January 2018

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21 January 2018

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Detection and localization of tumor necrosis factor-α in WHHL rabbit arteries

21 January 2018

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10.1152/AJPCELL.00477.2004

21 January 2018

Identifiers

DOI

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31 January 2017

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