Caspases and mitochondria in c-Myc-induced apoptosis: identification of ATM as a new target of caspases (Q28581404)

31 January 2017

title

Caspases and mitochondria in c-Myc-induced apoptosis: identification of ATM as a new target of caspases (English)

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31 January 2017

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A. Hotti

1

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31 January 2017

K. Järvinen

series ordinal

2

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31 January 2017

P. Siivola

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3

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31 January 2017

E. Hölttä

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4

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31 January 2017

language of work or name

English

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publication date

4 May 2000

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31 January 2017

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31 January 2017

volume

19

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31 January 2017

issue

19

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31 January 2017

page(s)

2354–2362

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Enhanced phosphorylation of p53 by ATM in response to DNA damage

31 January 2017

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Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization.

21 January 2018

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Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

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Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death

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DNA-dependent protein kinase is one of a subset of autoantigens specifically cleaved early during apoptosis

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Induction of apoptosis in fibroblasts by c-myc protein

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Cdc25 cell-cycle phosphatase as a target of c-myc

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Proteolytic activation of protein kinase C delta by an ICE/CED 3-like protease induces characteristics of apoptosis

21 January 2018

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Mitochondria and apoptosis

21 January 2018

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Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system

21 January 2018

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Requirement for the CD95 receptor-ligand pathway in c-Myc-induced apoptosis

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A functional role for death proteases in s-Myc- and c-Myc-mediated apoptosis

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Involvement of CPP32/Caspase-3 in c-Myc-induced apoptosis

21 January 2018

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A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

21 January 2018

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Mitochondrial control of apoptosis

21 January 2018

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

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A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins

21 January 2018

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A mutant p53 antagonizes the deregulated c-myc-mediated enhancement of apoptosis and decrease in leukemogenicity

21 January 2018

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Cloning, expression, and chromosomal localization of the 140-kilodalton subunit of replication factor C from mice and humans

21 January 2018

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Inhibition of Ced-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak

21 January 2018

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D4-GDI, a substrate of CPP32, is proteolyzed during Fas-induced apoptosis

21 January 2018

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Caspases: killer proteases

21 January 2018

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The CED-3/ICE-like protease Mch2 is activated during apoptosis and cleaves the death substrate lamin A

21 January 2018

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Ornithine decarboxylase is a mediator of c-Myc-induced apoptosis

21 January 2018

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Analysis of the membrane potential of rat- and mouse-liver mitochondria by flow cytometry and possible applications.

21 January 2018

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Activation of an MDM2-specific caspase by p53 in the absence of apoptosis

21 January 2018

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Mechanisms of apoptosis by c-Myc

21 January 2018

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A single ataxia telangiectasia gene with a product similar to PI-3 kinase

21 January 2018

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Interaction between ATM protein and c-Abl in response to DNA damage

21 January 2018

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A unique glucose-dependent apoptotic pathway induced by c-Myc

21 January 2018

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c-Myc transactivation of LDH-A: implications for tumor metabolism and growth

21 January 2018

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Cleavage and inactivation of ATM during apoptosis.

21 January 2018

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Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition.

21 January 2018

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Caspase-9 can be activated without proteolytic processing

21 January 2018

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The many roles of c-Myc in apoptosis

21 January 2018

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Effects of wild-type and mutated p53 and Id proteins on the induction of apoptosis by adenovirus E1A, c-Myc, Bax, and Nip3 in p53 null mouse cerebellum cells

21 January 2018

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Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1.

21 January 2018

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Transactivation-defective c-MycS retains the ability to regulate proliferation and apoptosis

21 January 2018

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Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo.

21 January 2018

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An anti-sense construct of full-length ATM cDNA imposes a radiosensitive phenotype on normal cells

21 January 2018

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Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

21 January 2018

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Recombinant ATM protein complements the cellular A-T phenotype

21 January 2018

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Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

21 January 2018

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Microfilament reorganization during apoptosis: the role of Gas2, a possible substrate for ICE-like proteases

21 January 2018

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7 January 2021

The central executioners of apoptosis: caspases or mitochondria?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203567

7 January 2021

Structural and functional analysis of poly(ADP ribose) polymerase: an immunological study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203567

7 January 2021

p53 and ATM: cell cycle, cell death, and cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203567

7 January 2021

A monoclonal antibody against a synthetic peptide reveals common structures among spectrins and alpha-actinin

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203567

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203567

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Dimensions Publication ID

31 January 2017

1042514403

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