Mitochondrial aldehyde dehydrogenase attenuates hyperoxia-induced cell death through activation of ERK/MAPK and PI3K-Akt pathways in lung epithelial cells (Q28582386)

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Language	Label	Description	Also known as
English	Mitochondrial aldehyde dehydrogenase attenuates hyperoxia-induced cell death through activation of ERK/MAPK and PI3K-Akt pathways in lung epithelial cells	scientific journal article

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scholarly article

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PubMed publication ID

31 January 2017

Mitochondrial aldehyde dehydrogenase attenuates hyperoxia-induced cell death through activation of ERK/MAPK and PI3K-Akt pathways in lung epithelial cells (English)

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PubMed publication ID

31 January 2017

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based on heuristic

inferred from title

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author name string

Dong Xu

1

1 reference

PubMed publication ID

31 January 2017

Jill R. Guthrie

2

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PubMed publication ID

31 January 2017

Sherry Mabry

3

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PubMed publication ID

31 January 2017

Thomas M. Sack

4

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PubMed publication ID

31 January 2017

William E. Truog

5

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PubMed publication ID

31 January 2017

publication date

1 November 2006

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PubMed publication ID

31 January 2017

American Journal of Physiology - Lung Cellular and Molecular Physiology

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PubMed publication ID

31 January 2017

291

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PubMed publication ID

31 January 2017

5

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PubMed publication ID

31 January 2017

L966–975

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PubMed publication ID

31 January 2017

Hypoxia protects human lung microvascular endothelial and epithelial-like cells against oxygen toxicity: role of phosphatidylinositol 3-kinase

1 reference

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Extracellular superoxide dismutase protects lung development in hyperoxia-exposed newborn mice

1 reference

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Pulmonary antioxidant defenses in the preterm newborn with respiratory distress and bronchopulmonary dysplasia in evolution: implications for antioxidant therapy

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Mitochondria, oxidants, and aging

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Control mechanisms of lung alveolar development and their disorders in bronchopulmonary dysplasia

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Reactive oxygen species are required for hyperoxia-induced Bax activation and cell death in alveolar epithelial cells

1 reference

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Identification of the enzymatic mechanism of nitroglycerin bioactivation

1 reference

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Acute activation of Erk1/Erk2 and protein kinase B/akt proceed by independent pathways in multiple cell types.

1 reference

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21 January 2018

Antioxidant responses to oxidant-mediated lung diseases

1 reference

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Hyperoxia-induced apoptosis and Fas/FasL expression in lung epithelial cells

1 reference

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Cyr61 protects against hyperoxia-induced cell death via Akt pathway in pulmonary epithelial cells

1 reference

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Overexpression of aldehyde dehydrogenase-2 (ALDH2) transgene prevents acetaldehyde-induced cell injury in human umbilical vein endothelial cells: role of ERK and p38 mitogen-activated protein kinase

1 reference

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21 January 2018

Activated Akt protects the lung from oxidant-induced injury and delays death of mice

1 reference

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21 January 2018

Hyperoxia-induced cell death in the lung--the correlation of apoptosis, necrosis, and inflammation

1 reference

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21 January 2018

Apoptosis and epithelial injury in the lungs

1 reference

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21 January 2018

Deficiency in a mitochondrial aldehyde dehydrogenase increases vulnerability to oxidative stress in PC12 cells

1 reference

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Mitochondrial ALDH2 Deficiency as an Oxidative Stress

1 reference

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Tissue-distribution of aldehyde dehydrogenase 2 and effects of the ALDH2 gene-disruption on the expression of enzymes involved in alcohol metabolism

1 reference

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21 January 2018

Alveolar cell death in hyperoxia-induced lung injury

1 reference

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Mitochondrial cytochromecrelease is a key event in hyperoxia-induced lung injury: protection by cyclosporin A

1 reference

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Transgenic overexpression of granulocyte macrophage-colony stimulating factor in the lung prevents hyperoxic lung injury

1 reference

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21 January 2018

NADPH oxidase and ERK signaling regulates hyperoxia-induced Nrf2-ARE transcriptional response in pulmonary epithelial cells

1 reference

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21 January 2018

Inducible expression of keratinocyte growth factor (KGF) in mice inhibits lung epithelial cell death induced by hyperoxia

1 reference

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21 January 2018

MAPK pathways mediate hyperoxia-induced oncotic cell death in lung epithelial cells

1 reference

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21 January 2018

Mitochondrial DNA damage triggers mitochondrial dysfunction and apoptosis in oxidant-challenged lung endothelial cells

1 reference

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Heme oxygenase-1: redox regulation of a stress protein in lung and cell culture models

1 reference

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Chronic vascular pulmonary dysplasia associated with neonatal hyperoxia exposure in the rat.

1 reference

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H2O2-induced proliferation of primary alveolar epithelial cells is mediated by MAP kinases

1 reference

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DNA strand break formation following exposure of bovine pulmonary artery and aortic endothelial cells to reactive oxygen products

1 reference

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Activation of an H2O2-generating NADH oxidase in human lung fibroblasts by transforming growth factor beta 1.

1 reference

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21 January 2018

Extracellular signal-regulated kinase activation delays hyperoxia-induced epithelial cell death in conditions of Akt downregulation

1 reference

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Necrotic Cell Death in Response to Oxidant Stress Involves the Activation of the Apoptogenic Caspase-8/Bid Pathway

1 reference

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Transgenic mice with expression of elevated levels of copper-zinc superoxide dismutase in the lungs are resistant to pulmonary oxygen toxicity

1 reference

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21 January 2018

A role for mitochondria as potential regulators of cellular life span

1 reference

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Developmental expression of aldehyde dehydrogenase in rat: a comparison of liver and lung development

1 reference

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Macrophages survive hyperoxia via prolonged ERK activation due to phosphatase down-regulation

1 reference

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21 January 2018

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