Pulmonary prostacyclin synthase overexpression in transgenic mice protects against development of hypoxic pulmonary hypertension (Q28582609)

2

1 reference

31 January 2017

D. C. Shepherd

3

1 reference

31 January 2017

M. D. Moore

4

1 reference

31 January 2017

J. Y. Westcott

5

1 reference

31 January 2017

K. A. Fagan

6

1 reference

31 January 2017

L. A. Alger

7

1 reference

31 January 2017

R. M. Tuder

8

1 reference

31 January 2017

N. F. Voelkel

Journal of Clinical Investigation

9

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31 January 2017

language of work or name

English

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publication date

1 June 1999

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31 January 2017

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31 January 2017

103

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31 January 2017

1509–1515

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31 January 2017

11

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31 January 2017

Molecular cloning and expression of human prostacyclin synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408370

Two SP-C genes encoding human pulmonary surfactant proteolipid

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408370

Prolonged endothelin A receptor blockade attenuates chronic pulmonary hypertension in the ovine fetus

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408370

Inhibition of 5-lipoxygenase-activating protein (FLAP) reduces pulmonary vascular reactivity and pulmonary hypertension in hypoxic rats

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408370

Molecular cloning and characterization of bovine prostacyclin synthase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408370

Isolation and molecular cloning of prostacyclin synthase from bovine endothelial cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408370

Pathology and pathophysiology of primary pulmonary hypertension

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408370

Interleukin 1: a mitogen for human vascular smooth muscle cells that induces the release of growth-inhibitory prostanoids

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408370

Cis-acting sequences from a human surfactant protein gene confer pulmonary-specific gene expression in transgenic mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408370

Prostacyclin production and mediation of adenylate cyclase activity in the pulmonary artery. Alterations after prolonged hypoxia in the rat

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408370

An imbalance between the excretion of thromboxane and prostacyclin metabolites in pulmonary hypertension

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408370

Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane A2, and prostacyclin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408370

A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408370

Overexpression of prostacyclin synthase inhibits growth of vascular smooth muscle cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408370

Prostacyclin in experimental myocardial ischemia: effects on hemodynamics, regional myocardial blood flow, infarct size and mortality

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408370

Analysis of 6-keto PGF1 alpha, 5-HETE, and LTC4 in rat lung: comparison of GM/MS, RIA, and EIA.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408370

Angiotensin II prevents hypoxic pulmonary hypertension and vascular changes in rat.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408370

Bovine prostacyclin synthase: purification and isolation of partial cDNA.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408370

Survival in primary pulmonary hypertension with long-term continuous intravenous prostacyclin

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408370

Targeted ablation of alpha-crystallin-synthesizing cells produces lens-deficient eyes in transgenic mice

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408370

Arterial walls generate from prostaglandin endoperoxides a substance (prostaglandin X) which relaxes strips of mesenteric and coeliac ateries and inhibits platelet aggregation

27 November 2018

1 reference

12 December 2020

Decreased arterial wall prostaglandin production in neonatal calves with severe chronic pulmonary hypertension

1 reference

12 December 2020

Agarose infiltration improves morphology of cryostat sections of lung

1 reference

12 December 2020

Effects of aerosolized prostacyclin in severe pneumonia. Impact of fibrosis

1 reference

12 December 2020

Inhaled nitric oxide versus inhaled prostacyclin and intravenous versus inhaled prostacyclin in acute respiratory failure with pulmonary hypertension in piglets

1 reference

12 December 2020

Direct comparison of inhaled nitric oxide and aerosolized prostacyclin in acute respiratory distress syndrome

1 reference

12 December 2020

Effects of acute and chronic hypoxia on rat lung cyclooxygenase

1 reference

12 December 2020

Prostacyclin synthase expression is decreased in lungs from patients with severe pulmonary hypertension

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI5911

1 reference

4336236

4336236

1 reference

1 reference

1 reference