The mechanism of potent GTP cyclohydrolase I inhibition by 2,4-diamino-6-hydroxypyrimidine: requirement of the GTP cyclohydrolase I feedback regulatory protein (Q28582766)

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English	The mechanism of potent GTP cyclohydrolase I inhibition by 2,4-diamino-6-hydroxypyrimidine: requirement of the GTP cyclohydrolase I feedback regulatory protein	scientific journal article

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scholarly article

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PubMed publication ID

31 January 2017

The mechanism of potent GTP cyclohydrolase I inhibition by 2,4-diamino-6-hydroxypyrimidine: requirement of the GTP cyclohydrolase I feedback regulatory protein (English)

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PubMed publication ID

31 January 2017

author name string

Monica A. Kolinsky

1

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PubMed publication ID

31 January 2017

Steven S. Gross

2

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PubMed publication ID

31 January 2017

language of work or name

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publication date

24 September 2004

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PubMed publication ID

31 January 2017

Journal of Biological Chemistry

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PubMed publication ID

31 January 2017

279

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PubMed publication ID

31 January 2017

39

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PubMed publication ID

31 January 2017

40677–40682

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PubMed publication ID

31 January 2017

THE STRUCTURE OF THE PHENYLALANINE-HYDROXYLATION COFACTOR

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21 January 2018

Tryptophan hydroxylation: measurement in pineal gland, brainstem, and carcinoid tumor.

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Biosynthesis and metabolism of tetrahydrobiopterin and molybdopterin

1 reference

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Hereditary progressive dystonia with marked diurnal fluctuation caused by mutations in the GTP cyclohydrolase I gene

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Tetrahydrobiopterin metabolism in the temporal lobe of patients dying with senile dementia of Alzheimer type

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Hydroxylase Cofactor Activity in Cerebrospinal Fluid of Normal Subjects and Patients with Parkinson's Disease

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Vitamin C improves endothelium-dependent vasodilation in patients with insulin-dependent diabetes mellitus.

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Vitamin C improves endothelium-dependent vasodilation in patients with non-insulin-dependent diabetes mellitus

1 reference

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Tetrahydrobiopterin improves endothelium-dependent vasodilation in chronic smokers : evidence for a dysfunctional nitric oxide synthase

1 reference

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Tetrahydrobiopterin restores endothelial function in hypercholesterolemia.

1 reference

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Biopterin : II. Evidence for cerebral synthesis of 7,8-dihydrobiopterin in vivo and in vitro

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A model for hyperphenylalaninaemia due to tetrahydrobiopterin deficiency

1 reference

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Decrease in tetrahydrobiopterin content and neurotransmitter amine biosynthesis in rat brain by an inhibitor of guanosine triphosphate cyclohydrolase

1 reference

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21 January 2018

Cytokine-activated endothelial cells express an isotype of nitric oxide synthase which is tetrahydrobiopterin-dependent, calmodulin-independent and inhibited by arginine analogs with a rank-order of potency characteristic of activated macrophages

1 reference

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21 January 2018

Pterins inhibit nitric oxide synthase activity in rat alveolar macrophages

1 reference

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21 January 2018

Tetrahydrobiopterin deficiency increases neuronal vulnerability to hypoxia

1 reference

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21 January 2018

Feedback regulation mechanisms for the control of GTP cyclohydrolase I activity

1 reference

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Purification and cloning of the GTP cyclohydrolase I feedback regulatory protein, GFRP

1 reference

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21 January 2018

Decameric GTP cyclohydrolase I forms complexes with two pentameric GTP cyclohydrolase I feedback regulatory proteins in the presence of phenylalanine or of a combination of tetrahydrobiopterin and GTP

1 reference

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21 January 2018

GTP cyclohydrolase I feedback regulatory protein is a pentamer of identical subunits. Purification, cDNA cloning, and bacterial expression

1 reference

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21 January 2018

GTP cyclohydrolase I inhibition by the prototypic inhibitor 2, 4-diamino-6-hydroxypyrimidine. Mechanisms and unanticipated role of GTP cyclohydrolase I feedback regulatory protein

1 reference

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21 January 2018

Biosynthesis of pteridines. Stopped-flow kinetic analysis of GTP cyclohydrolase I.

1 reference

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21 January 2018

Zinc plays a key role in human and bacterial GTP cyclohydrolase I

1 reference

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21 January 2018

GTP cyclohydrolase I feedback regulatory protein-dependent and -independent inhibitors of GTP cyclohydrolase I.

1 reference

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21 January 2018

Phenylalanine improves dilation and blood pressure in GTP cyclohydrolase inhibition-induced hypertensive rats

1 reference

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21 January 2018

Biosynthesis of pteridines. Reaction mechanism of GTP cyclohydrolase I

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M405370200

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https://api.fatcat.wiki/v0/release/cntiaq3j6jecbh3nxgaatlbhae

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