Exposure of glia to pro-oxidant agents revealed selective Stat1 activation by H2O2 and Jak2-independent antioxidant features of the Jak2 inhibitor AG490 (Q28583129)

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English	Exposure of glia to pro-oxidant agents revealed selective Stat1 activation by H2O2 and Jak2-independent antioxidant features of the Jak2 inhibitor AG490	scientific journal article

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scholarly article

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31 January 2017

Exposure of glia to pro-oxidant agents revealed selective Stat1 activation by H2O2 and Jak2-independent antioxidant features of the Jak2 inhibitor AG490 (English)

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31 January 2017

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author name string

Roser Gorina

1

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31 January 2017

Coral Sanfeliu

2

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31 January 2017

Aida Galitó

3

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31 January 2017

Angel Messeguer

4

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31 January 2017

Anna M. Planas

5

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31 January 2017

publication date

1 October 2007

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31 January 2017

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31 January 2017

55

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31 January 2017

13

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31 January 2017

1313–1324

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31 January 2017

A road map for those who don't know JAK-STAT

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The mechanism of initiation of lipid peroxidation. Evidence against a requirement for an iron(II)-iron(III) complex

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Oxidative stress triggers STAT3 tyrosine phosphorylation and nuclear translocation in human lymphocytes

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STATs and gene regulation

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STAT1 as a new molecular target of anti-inflammatory treatment

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JAK/STAT signaling pathway mediates cytokine-induced iNOS expression in primary astroglial cell cultures

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AG490 prevents cell death after exposure of rat astrocytes to hydrogen peroxide or proinflammatory cytokines: involvement of the Jak2/STAT pathway

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A positive autoregulatory loop of Jak-STAT signaling controls the onset of astrogliogenesis

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JAK/STAT-dependent gene regulation by cytokines.

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Activation of the JAK/STAT pathway following transient focal cerebral ischemia: signaling through Jak1 and Stat3 in astrocytes

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Methodology for studying antioxidant activity and mechanisms of action of antioxidants

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JAK-STAT signaling mediates gangliosides-induced inflammatory responses in brain microglial cells

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Jaks and STATs: biological implications

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Stats: transcriptional control and biological impact

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Reactive oxygen species regulate heat-shock protein 70 via the JAK/STAT pathway

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Activation of JAK2 by the oxidative stress generated with oxidized low-density lipoprotein

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Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor

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Signaling through JAK2-STAT5 pathway is essential for IL-3-induced activation of microglia

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Cytokine signaling in 2002: new surprises in the Jak/Stat pathway

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Induction of Stat3, a signal transducer and transcription factor, in reactive microglia following transient focal cerebral ischaemia.

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Stat1 in developing and adult rat brain. Induction after transient focal ischemia.

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Mechanisms of type-I- and type-II-interferon-mediated signalling

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The JAK/STAT signaling pathway

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Dimethyl sulfoxide prevents DNA nicking mediated by ionizing radiation or iron/hydrogen peroxide-generated hydroxyl radical

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Identification of 1,2,3,4,5,6-hexabromocyclohexane as a small molecule inhibitor of jak2 tyrosine kinase autophosphorylation [correction of autophophorylation].

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High-yield isolation of murine microglia by mild trypsinization.

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Oxidative chemistry of nitric oxide: the roles of superoxide, peroxynitrite, and carbon dioxide

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Induction of gp130-related Cytokines and Activation of JAK2/STAT3 Pathway in Astrocytes Precedes Up-regulation of Glial Fibrillary Acidic Protein in the 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Model of Neurodegeneration

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Hydrogen peroxide scavenging, antioxidant and anti-radical activity of some phenolic acids

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Activation of transcription factors by drugs inducing oxidative stress in rat liver.

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Hyperglycemia and reactive oxygen species mediate apoptosis in aortic endothelial cells through Janus kinase 2.

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An evaluation of the antioxidant and potential pro-oxidant properties of food additives and of trolox C, vitamin E and probucol

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Superoxide production in rat hippocampal neurons: selective imaging with hydroethidine

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Determination of malonaldehyde in biological materials by high-pressure liquid chromatography

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The control of iron-induced oxidative damage in isolated rat-liver mitochondria by respiration state and ascorbate

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The autoxidation of iron(II) in aqueous systems: the effects of iron chelation by physiological, non-physiological and therapeutic chelators on the generation of reactive oxygen species and the inducement of biomolecular damage

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Characterization of N-acetylcysteine and ambroxol in anti-oxidant therapy

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Ciliary neurotrophic factor activates JAK/Stat signal transduction cascade and induces transcriptional expression of glial fibrillary acidic protein in glial cells

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Evaluation of the probe 2',7'-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress

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Oxidized LDL activates STAT1 and STAT3 transcription factors: possible involvement of reactive oxygen species

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Effect of extracellular Mg(2+) on ROS and Ca(2+) accumulation during reoxygenation of rat cardiomyocytes

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Activation of the JAK-STAT pathway by reactive oxygen species.

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Role of the JAK-STAT pathway in protection of hydrogen peroxide preconditioning against apoptosis induced by oxidative stress in PC12 cells

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7 January 2021

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Identifiers

10.1002/GLIA.20542

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31 January 2017

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31 January 2017

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