Characterization of the gene expression profile of heterozygous liver-specific glucokinase knockout mice at a young age (Q28584877)

31 January 2017

title

Characterization of the gene expression profile of heterozygous liver-specific glucokinase knockout mice at a young age (English)

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31 January 2017

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GOA release 2020-03-11

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Tingting Guo

1

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31 January 2017

Yiqing Mao

2

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31 January 2017

Hui Li

3

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31 January 2017

Xi Wang

4

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31 January 2017

Wei Xu

5

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31 January 2017

Rongjing Song

6

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31 January 2017

Jianwei Jia

7

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31 January 2017

Zhen Lei

8

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31 January 2017

David M. Irwin

9

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31 January 2017

Gang Niu

10

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31 January 2017

Huanran Tan

11

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31 January 2017

publication date

1 December 2012

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Biomedicine and Pharmacotherapy

31 January 2017

published in

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31 January 2017

volume

66

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31 January 2017

issue

8

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31 January 2017

page(s)

587–596

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Molecular physiology of mammalian glucokinase

31 January 2017

cites work

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17 March 2017

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Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

17 March 2017

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17 March 2017

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Animal Model for Maturity-onset Diabetes of the Young Generated by Disruption of the Mouse Glucokinase Gene

17 March 2017

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The network of glucokinase-expressing cells in glucose homeostasis and the potential of glucokinase activators for diabetes therapy

29 September 2017

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29 September 2017

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29 September 2017

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Identification of upstream stimulatory factor as transcriptional activator of the liver promoter of the glucokinase gene

29 September 2017

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Correction of diabetic alterations by glucokinase.

29 September 2017

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Differential effects of overexpressed glucokinase and hexokinase I in isolated islets. Evidence for functional segregation of the high and low Km enzymes

29 September 2017

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29 September 2017

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Glucokinase as pancreatic beta cell glucose sensor and diabetes gene

29 September 2017

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Lilly lecture 1987. The triumvirate: beta-cell, muscle, liver. A collusion responsible for NIDDM.

29 September 2017

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Glucokinase as glucose sensor and metabolic signal generator in pancreatic beta-cells and hepatocytes

29 September 2017

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Tissue-specific regulation of glucokinase gene expression

29 September 2017

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Overexpression of apolipoprotein E in transgenic mice: marked reduction in plasma lipoproteins except high density lipoprotein and resistance against diet-induced hypercholesterolemia

29 September 2017

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Improved metabolic disorders of insulin receptor-deficient mice by transgenic overexpression of glucokinase in the liver

29 September 2017

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Mechanisms by which carbohydrates regulate expression of genes for glycolytic and lipogenic enzymes.

3 June 2018

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Requirement of glucose metabolism for regulation of glucose transporter type 2 (GLUT2) gene expression in liver

3 June 2018

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Hexokinase II mRNA and gene structure, regulation by insulin, and evolution

3 June 2018

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Human hexokinase II mRNA and gene structure

3 June 2018

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Studies on isozymes of hexokinase in animal tissues

3 June 2018

1 reference

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Glucose regulates glucokinase activity in cultured islets from rat pancreas

3 June 2018

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Linkage of type 2 diabetes to the glucokinase gene

3 June 2018

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Insulin signalling and regulation of glucokinase gene expression in cultured hepatocytes

3 June 2018

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Evaluating the glucose tolerance test in mice

3 June 2018

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Regulation of SREBP-1 expression and transcriptional action on HKII and FAS genes during fasting and refeeding in rat tissues

27 November 2018

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Establishment of liver specific glucokinase gene knockout mice: a new animal model for screening anti-diabetic drugs.

27 November 2018

1 reference

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A modest glucokinase overexpression in the liver promotes fed expression levels of glycolytic and lipogenic enzyme genes in the fasted state without altering SREBP-1c expression

27 November 2018

1 reference

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Liver hyperplasia and paradoxical regulation of glycogen metabolism and glucose-sensitive gene expression in GLUT2-null hepatocytes. Further evidence for the existence of a membrane-based glucose release pathway.

27 November 2018

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Metabolic impact of glucokinase overexpression in liver: lowering of blood glucose in fed rats is accompanied by hyperlipidemia.

27 November 2018

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Assessment of insulin sensitivity in glucokinase-deficient subjects.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729386

Tissue distribution and physiological significance of multiple forms of hexokinase.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729386

Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulin-dependent diabetes mellitus

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729386

Stimulation by insulin of glucokinase gene transcription in liver of diabetic rats

27 November 2018

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12 December 2020

The Effects of Hyperinsulinemia and Hyperglycemia on GLUT4 and Hexokinase II mRNA and Protein in Rat Skeletal Muscle and Adipose Tissue

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12 December 2020

GLUT2 expression and function in beta-cells of GK rats with NIDDM. Dissociation between reductions in glucose transport and glucose-stimulated insulin secretion

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12 December 2020

Liver glucokinase: decreased activity in patients with type II diabetes

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12 December 2020

Regulation of hexokinase II and glycogen synthase mRNA, protein, and activity in human muscle

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12 December 2020

Differential Metabolic Effects of Adenovirus-mediated Glucokinase and Hexokinase I Overexpression in Rat Primary Hepatocytes

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12 December 2020

The loss of GLUT2 expression in the pancreatic β-cells of diabetic db/db mice is associated with an impaired DNA-binding activity of islet-specific trans-acting factors

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12 December 2020

INSULIN-DEPENDENT SYNTHESIS OF LIVER GLUCOKINASE IN THE RAT

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12 December 2020

Glucagon receptor knockout mice are resistant to diet-induced obesity and streptozotocin-mediated beta cell loss and hyperglycaemia

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12 December 2020

Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction

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12 December 2020

The effect of insulin on the disposal of intravenous glucose. Results from indirect calorimetry and hepatic and femoral venous catheterization

1 reference

12 December 2020

10.1016/J.BIOPHA.2012.07.002

Identifiers

DOI

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31 January 2017

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