Exacerbation of retinal degeneration in the absence of alpha crystallins in an in vivo model of chemically induced hypoxia (Q28585065)

31 January 2017

title

Exacerbation of retinal degeneration in the absence of alpha crystallins in an in vivo model of chemically induced hypoxia (English)

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31 January 2017

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GOA release 2020-03-11

Crystallin, alpha A

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GOA release 2020-03-11

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Jennifer Yaung

1

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31 January 2017

Ram Kannan

2

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31 January 2017

Eric F. Wawrousek

3

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31 January 2017

Christine Spee

4

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31 January 2017

Parameswaran G. Sreekumar

5

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31 January 2017

David R. Hinton

6

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31 January 2017

publication date

1 February 2008

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Experimental Eye Research

31 January 2017

published in

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31 January 2017

volume

86

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31 January 2017

issue

2

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31 January 2017

page(s)

355–365

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Vascular endothelial growth factor-A is a survival factor for retinal neurons and a critical neuroprotectant during the adaptive response to ischemic injury.

31 January 2017

cites work

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alpha-Crystallin distribution in retinal pigment epithelium and effect of gene knockouts on sensitivity to oxidative stress

17 March 2017

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Human alphaA- and alphaB-crystallins bind to Bax and Bcl-X(S) to sequester their translocation during staurosporine-induced apoptosis

17 March 2017

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

17 March 2017

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AlphaB-crystallin in lens development and muscle integrity: a gene knockout approach

17 March 2017

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Targeted disruption of the mouse alpha A-crystallin gene induces cataract and cytoplasmic inclusion bodies containing the small heat shock protein alpha B-crystallin

17 March 2017

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alpha A-crystallin is expressed in non-ocular tissues

17 March 2017

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Alpha-crystallin can function as a molecular chaperone

17 March 2017

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Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

7 April 2017

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Small heat shock protein alphaB-crystallin binds to p53 to sequester its translocation to mitochondria during hydrogen peroxide-induced apoptosis

7 April 2017

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Crystallins in the eye: Function and pathology

29 September 2017

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29 September 2017

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Photochemical damage of the retina

29 September 2017

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Hypoxia-mimetic agents desferrioxamine and cobalt chloride induce leukemic cell apoptosis through different hypoxia-inducible factor-1alpha independent mechanisms

29 September 2017

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Long-term effect of therapeutic laser photocoagulation on gene expression in the eye.

29 September 2017

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Synaptic pathology, altered gene expression, and degeneration in photoreceptors impacted by drusen

29 September 2017

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Hsp27 upregulation by HIF-1 signaling offers protection against retinal ischemia in rats.

29 September 2017

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The small heat shock protein alpha B-crystallin is a novel inhibitor of TRAIL-induced apoptosis that suppresses the activation of caspase-3.

29 September 2017

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Transparency and non-refractive functions of crystallins--a proposal

29 September 2017

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Critical role of mitochondrial glutathione in the survival of hepatocytes during hypoxia

29 September 2017

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Cobalt chloride-induced apoptosis and extracellular signal-regulated protein kinase 1/2 activation in rat C6 glioma cells

29 September 2017

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Inherited retinal degenerations: therapeutic prospects

29 September 2017

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Gene expression profiling of the hypoxia signaling pathway in hypoxia-inducible factor 1alpha null mouse embryonic fibroblasts

29 September 2017

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Retinal oxygen: fundamental and clinical aspects

29 September 2017

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Retinal pigment epithelium is protected against apoptosis by alphaB-crystallin.

29 September 2017

1 reference

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Drusen proteome analysis: an approach to the etiology of age-related macular degeneration.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731668

Alpha-crystallin as a molecular chaperone

29 September 2017

1 reference

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Structure and function in rhodopsin: correct folding and misfolding in point mutants at and in proximity to the site of the retinitis pigmentosa mutation Leu-125-->Arg in the transmembrane helix C.

29 September 2017

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Retinal degeneration in the rd mouse is caused by a defect in the beta subunit of rod cGMP-phosphodiesterase

29 September 2017

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Differential expression of pro- and antiangiogenic factors in mouse strain-dependent hypoxia-induced retinal neovascularization

29 September 2017

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Protective and therapeutic role for alphaB-crystallin in autoimmune demyelination

3 June 2018

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Transfer of lens-specific transcripts to retinal RNA samples may underlie observed changes in crystallin-gene transcript levels after ischemia.

27 November 2018

1 reference

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Hypoxia/reoxygenation and TGF-beta increase alphaB-crystallin expression in human optic nerve head astrocytes.

27 November 2018

1 reference

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Toxic effects of cobalt in primary cultures of mouse astrocytes

27 November 2018

1 reference

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A new model of retinal photoreceptor cell degeneration induced by a chemical hypoxia-mimicking agent, cobalt chloride

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731668

Dicarbonyl stress and apoptosis of vascular cells: prevention by alphaB-crystallin

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731668

Retinal Neuroprotection against Ischemic Injury Mediated by Intraocular Gene Transfer of Pigment Epithelium-Derived Factor

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731668

A comprehensive analysis of the expression of crystallins in mouse retina

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731668

Inhibition of proteasome activity is involved in cobalt-induced apoptosis of human alveolar macrophages

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731668

A rhodopsin mutant linked to autosomal dominant retinitis pigmentosa is prone to aggregate and interacts with the ubiquitin proteasome system

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731668

The small heat shock protein alpha B-crystallin negatively regulates cytochrome c- and caspase-8-dependent activation of caspase-3 by inhibiting its autoproteolytic maturation

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731668

Expression of alphaB-crystallin in a mouse model of inherited retinal degeneration

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731668

Glut1 and glut3 expression, but not capillary density, is increased by cobalt chloride in rat cerebrum and retina

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731668

Tissue oxygen during a critical developmental period controls the death and survival of photoreceptors.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731668

Cobalt chloride induces PC12 cells apoptosis through reactive oxygen species and accompanied by AP-1 activation

27 November 2018

1 reference

12 December 2020

Transcriptional repression of the human p53 gene by cobalt chloride mimicking hypoxia

1 reference

12 December 2020

Modified alpha A crystallin in the retina: altered expression and truncation with aging

1 reference

12 December 2020

Photoreceptor dystrophy in the RCS rat: roles of oxygen, debris, and bFGF

1 reference

12 December 2020

Crystallin distribution in Bruch's membrane-choroid complex from AMD and age-matched donor eyes

1 reference

12 December 2020

Genetic, age and light mediated effects on crystallin protein expression in the retina

1 reference

12 December 2020

Human retinal pigment epithelium cell changes and expression of alphaB-crystallin: a biomarker for retinal pigment epithelium cell change in age-related macular degeneration

1 reference

12 December 2020

Interactions between important regulatory proteins and human alphaB crystallin

1 reference

12 December 2020

The spatio-temporal pattern of photoreceptor degeneration in the aged rd/rd mouse retina

1 reference

12 December 2020

10.1016/J.EXER.2007.11.007

Identifiers

DOI

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31 January 2017

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