Wwp2 mediates Oct4 ubiquitination and its own auto-ubiquitination in a dosage-dependent manner (Q28585636)

New type of POU domain in germ line-specific protein Oct-4

GOA release 2020-03-11

protein ubiquitination

1 reference

Bing Liao

1

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31 January 2017

Ying Jin

series ordinal

2

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31 January 2017

1 March 2010

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31 January 2017

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31 January 2017

20

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31 January 2017

3

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31 January 2017

332–344

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31 January 2017

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Oct-4 transcription factor is differentially expressed in the mouse embryo during establishment of the first two extraembryonic cell lineages involved in implantation

21 April 2017

1 reference

Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells

21 April 2017

1 reference

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

21 April 2017

1 reference

The ubiquitin ligase HectH9 regulates transcriptional activation by Myc and is essential for tumor cell proliferation

21 April 2017

1 reference

UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover

21 April 2017

1 reference

Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis

21 April 2017

1 reference

The C2 domain of the Rsp5 ubiquitin ligase binds membrane phosphoinositides and directs ubiquitination of endosomal cargo

21 April 2017

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A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase

21 April 2017

1 reference

The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules

21 April 2017

1 reference

Specificity and Autoregulation of Notch Binding by Tandem WW Domains in Suppressor of Deltex

21 April 2017

1 reference

WW domains provide a platform for the assembly of multiprotein networks

21 April 2017

1 reference

21 April 2017

1 reference

Rad6B is a positive regulator of beta-catenin stabilization

21 April 2017

1 reference

Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli

21 April 2017

1 reference

Regulation of Nedd4-2 self-ubiquitination and stability by a PY motif located within its HECT-domain

21 April 2017

1 reference

Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation

21 April 2017

1 reference

Wwp2, an E3 ubiquitin ligase that targets transcription factor Oct-4 for ubiquitination

21 April 2017

1 reference

Polyubiquitin chains: polymeric protein signals

21 April 2017

1 reference

Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex

21 April 2017

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Autoinhibition of the HECT-type ubiquitin ligase Smurf2 through its C2 domain

21 April 2017

1 reference

The BRCA1/BARD1 heterodimer assembles polyubiquitin chains through an unconventional linkage involving lysine residue K6 of ubiquitin

21 April 2017

1 reference

Lysine 63-linked polyubiquitin chain may serve as a targeting signal for the 26S proteasome

21 April 2017

1 reference

Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na(+) channel cell surface expression

21 April 2017

1 reference

Identification of novel human WW domain-containing proteins by cloning of ligand targets

21 April 2017

1 reference

Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation

21 April 2017

1 reference

Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.136

Regulation of Oct-4 gene expression during differentiation of EC cells.

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.136

Oct4-induced pluripotency in adult neural stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.136

Itch: a HECT-type E3 ligase regulating immunity, skin and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.136

WW or WoW: the WW domains in a union of bliss

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.136

The ubiquitin-proteasome proteolytic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.136

The ubiquitin system for protein degradation and some of its roles in the control of the cell division cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.136

Certain pairs of ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) synthesize nondegradable forked ubiquitin chains containing all possible isopeptide linkages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.136

Lysine 63 polyubiquitination of the nerve growth factor receptor TrkA directs internalization and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.136

In vitro assembly and recognition of Lys-63 polyubiquitin chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.136

The ubiquitin-protein ligase E6-associated protein (E6-AP) serves as its own substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.136

Aggregation of embryonic stem cells induces Nanog repression and primitive endoderm differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.136

Jun turnover is controlled through JNK-dependent phosphorylation of the E3 ligase Itch

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.136

Regulation of catalytic activities of HECT ubiquitin ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.136

Differences between human and mouse embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.136

Wwp2-mediated ubiquitination of the RNA polymerase II large subunit in mouse embryonic pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.136

Post-translational modification of POU domain transcription factor Oct-4 by SUMO-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.136

Molecular mechanisms of coupled monoubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.136

UBC13, a DNA-damage-inducible gene, is a member of the error-free postreplication repair pathway in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.136

7 January 2021

The Polycomb Protein Ring1B Generates Self Atypical Mixed Ubiquitin Chains Required for Its In Vitro Histone H2A Ligase Activity

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.136

7 January 2021

Biphasic response to retinoic acid dose in differentiation of F9 cells into primitive endoderm-like cells

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.136

7 January 2021

The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.136

7 January 2021