Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation (Q28586360)

GOA release 2020-03-11

8

A. Ashworth

1 reference

31 January 2017

F. Connor

1

1 reference

31 January 2017

D. Bertwistle

2

1 reference

31 January 2017

P. J. Mee

3

1 reference

31 January 2017

G. M. Ross

4

1 reference

31 January 2017

S. Swift

5

1 reference

31 January 2017

E. Grigorieva

6

1 reference

31 January 2017

V. L. Tybulewicz

Association of BRCA1 with Rad51 in mitotic and meiotic cells

7

1 reference

31 January 2017

language of work or name

English

0 references

publication date

1 December 1997

1 reference

31 January 2017

1 reference

31 January 2017

17

1 reference

31 January 2017

4

1 reference

31 January 2017

423–430

1 reference

31 January 2017

1 reference

Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

21 April 2017

1 reference

BRCA1 is a component of the RNA polymerase II holoenzyme

21 April 2017

1 reference

Cancer-susceptibility genes. Gatekeepers and caretakers

21 April 2017

1 reference

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

21 April 2017

1 reference

Identification of the breast cancer susceptibility gene BRCA2

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

Hereditary predisposition to breast cancer

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

BRCA2 mutations in primary breast and ovarian cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

Mutation analysis in the BRCA2 gene in primary breast cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

Low incidence of BRCA2 mutations in breast carcinoma and other cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

Internal repeats in the BRCA2 protein sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

The BRC repeats are conserved in mammalian BRCA2 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

Cloning, chromosomal mapping and expression pattern of the mouse Brca2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

Murine Brca2: sequence, map position, and expression pattern.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

Brca2 is coordinately regulated with Brca1 during proliferation and differentiation in mammary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

21 January 2018

DNA repair: RAD alert

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

A single BRCA2 mutation in male and female breast cancer families from Iceland with varied cancer phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

Pleiotropic defects in ataxia-telangiectasia protein-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

Breast and other cancers in families with ataxia-telangiectasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

Heterozygous ATM mutations do not contribute to early onset of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

Double indemnity: p53, BRCA and cancer. p53 mutation partially rescues developmental arrest in Brca1 and Brca2 null mice, suggesting a role for familial breast cancer genes in DNA damage repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

Transcriptional activation by BRCA1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

Inherited breast and ovarian cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

7 January 2021

Breast cancer genes--what are the real risks?

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

7 January 2021

Linkage of early-onset familial breast cancer to chromosome 17q21

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

7 January 2021

A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

7 January 2021

Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13.

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

7 January 2021

BRCA1 mutations in primary breast and ovarian carcinomas.

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

7 January 2021

Variation of risks of breast and ovarian cancer associated with different germline mutations of the BRCA2 gene

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

7 January 2021

Transcriptional activation functions in BRCA2

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

7 January 2021

Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

7 January 2021

Brca2 is required for embryonic cellular proliferation in the mouse

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

7 January 2021

Inactivation of the mouse Brca1 gene leads to failure in the morphogenesis of the egg cylinder in early postimplantation development.

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

7 January 2021

Wild-type p53 transgenic mice exhibit altered differentiation of the ureteric bud and possess small kidneys

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

7 January 2021

Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

7 January 2021

Atm-deficient mice: a paradigm of ataxia telangiectasia

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

7 January 2021

p53 mutations in BRCA1-associated familial breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

7 January 2021

Abnormal centrosome amplification in the absence of p53.

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

7 January 2021

Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene

1 reference

https://api.crossref.org/works/10.1038%2FNG1297-423

7 January 2021