Metabolites from apoptotic thymocytes inhibit thymopoiesis in adenosine deaminase-deficient fetal thymic organ cultures (Q28586537)

31 January 2017

title

Metabolites from apoptotic thymocytes inhibit thymopoiesis in adenosine deaminase-deficient fetal thymic organ cultures (English)

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31 January 2017

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GOA release 2020-03-11

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L. F. Thompson

1

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31 January 2017

C. J. Van de Wiele

2

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31 January 2017

A. B. Laurent

3

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31 January 2017

S. W. Hooker

4

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31 January 2017

J. G. Vaughn

5

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31 January 2017

H. Jiang

6

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31 January 2017

K. Khare

7

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31 January 2017

R. E. Kellems

8

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31 January 2017

M. R. Blackburn

9

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31 January 2017

M. S. Hershfield

10

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31 January 2017

R. Resta

11

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31 January 2017

language of work or name

English

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publication date

1 November 2000

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Journal of Clinical Investigation

31 January 2017

published in

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31 January 2017

volume

106

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31 January 2017

issue

9

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31 January 2017

page(s)

1149–1157

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An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

31 January 2017

cites work

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Adenosine deaminase-deficient mice generated using a two-stage genetic engineering strategy exhibit a combined immunodeficiency

17 March 2017

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17 March 2017

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Disruption of the adenosine deaminase gene causes hepatocellular impairment and perinatal lethality in mice

17 March 2017

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Adenosine–deaminase–deficient mice die perinatally and exhibit liver–cell degeneration, atelectasis and small intestinal cell death

17 March 2017

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17 March 2017

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17 March 2017

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17 March 2017

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Insights into thymic purine metabolism and adenosine deaminase deficiency revealed by transgenic mice overexpressing ecto-5'-nucleotidase (CD73).

29 September 2017

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29 September 2017

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A dominant-negative transgene defines a role for p56lck in thymopoiesis

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Effects of deoxycoformycin in mice. III. A murine model reproducing multi-system pathology of human adenosine deaminase deficiency

29 September 2017

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A murine early thymocyte developmental sequence is marked by transient expression of the interleukin 2 receptor

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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3 June 2018

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Productive T-cell receptor beta-chain gene rearrangement: coincident regulation of cell cycle and clonality during development in vivo.

3 June 2018

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A novel disulfide-linked heterodimer on pre-T cells consists of the T cell receptor beta chain and a 33 kd glycoprotein

3 June 2018

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3 June 2018

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bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes

3 June 2018

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Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages

3 June 2018

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On the role of the pre-T cell receptor in alphabeta versus gammadelta T lineage commitment

3 June 2018

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dATP causes specific release of cytochrome C from mitochondria

27 November 2018

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Notch activity influences the alphabeta versus gammadelta T cell lineage decision

27 November 2018

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Exogenous IL-7 promotes the growth of CD3-CD4-CD8-CD44+CD25+/- precursor cells and blocks the differentiation pathway of TCR-alpha beta cells in fetal thymus organ culture.

27 November 2018

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The use of enzyme therapy to regulate the metabolic and phenotypic consequences of adenosine deaminase deficiency in mice. Differential impact on pulmonary and immunologic abnormalities

27 November 2018

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12 December 2020

Immature thymocytes employ distinct signaling pathways for allelic exclusion versus differentiation and expansion

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12 December 2020

T gamma cells express T lymphocyte-associated antigens

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12 December 2020

Deoxyadenosine triphosphate accumulation in erythrocytes of deoxycoformycin-treated mice

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12 December 2020

Onset of TCR-beta gene rearrangement and role of TCR-beta expression during CD3-CD4-CD8- thymocyte differentiation

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12 December 2020

T-cell apoptosis detected in situ during positive and negative selection in the thymus

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12 December 2020

Crucial role of the pre-T-cell receptor α gene in development of ap but not γδ T cells

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12 December 2020

Adenosine-deaminase deficiency in two patients with severely impaired cellular immunity

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12 December 2020

Identifiers

DOI

10.1172/JCI9944

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