Targeted inactivation of the isoprenylcysteine carboxyl methyltransferase gene causes mislocalization of K-Ras in mammalian cells (Q28586789)

31 January 2017

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5 November 2019

title

Targeted inactivation of the isoprenylcysteine carboxyl methyltransferase gene causes mislocalization of K-Ras in mammalian cells (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10747846%20AND%20SRC:MED&resulttype=core&format=json

Isoprenylcysteine carboxyl methyltransferase

5 November 2019

main subject

1 reference

GOA release 2020-03-11

author

Stephen G. Young

6

1 reference

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5 November 2019

author name string

Bergo MO

1

1 reference

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5 November 2019

Leung GK

2

1 reference

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5 November 2019

Ambroziak P

3

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5 November 2019

Otto JC

4

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5 November 2019

Casey PJ

5

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5 November 2019

language of work or name

English

0 references

publication date

1 June 2000

1 reference

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Journal of Biological Chemistry

5 November 2019

published in

2 references

31 January 2017

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5 November 2019

volume

275

2 references

31 January 2017

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5 November 2019

issue

23

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31 January 2017

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5 November 2019

page(s)

17605-17610

1 reference

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Protein prenylation: molecular mechanisms and functional consequences

5 November 2019

cites work

1 reference

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Endoplasmic reticulum membrane localization of Rce1p and Ste24p, yeast proteases involved in carboxyl-terminal CAAX protein processing and amino-terminal a-factor cleavage

21 January 2018

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Posttranslational modification of the Ha-ras oncogene protein: evidence for a third class of protein carboxyl methyltransferases

21 January 2018

1 reference

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Protein prenyltransferases

21 January 2018

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Inhibitors of Ras farnesyltransferases

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Farnesyltransferase inhibitors versus Ras inhibitors.

21 January 2018

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Nucleotide sequence of the yeast STE14 gene, which encodes farnesylcysteine carboxyl methyltransferase, and demonstration of its essential role in a-factor export

21 January 2018

1 reference

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The Saccharomyces cerevisiae prenylcysteine carboxyl methyltransferase Ste14p is in the endoplasmic reticulum membrane

21 January 2018

1 reference

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Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum

21 January 2018

1 reference

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A single activity carboxyl methylates both farnesyl and geranylgeranyl cysteine residues

21 January 2018

1 reference

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Prenylated protein methyltransferases do not distinguish between farnesylated and geranylgeranylated substrates

21 January 2018

1 reference

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Dislodgment and accelerated degradation of Ras.

21 January 2018

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Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2

21 January 2018

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Disruption of the acyl-CoA:cholesterol acyltransferase gene in mice: evidence suggesting multiple cholesterol esterification enzymes in mammals

21 January 2018

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The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain

21 January 2018

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Production of homozygous mutant ES cells with a single targeting construct

21 January 2018

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Cloning and characterization of a mammalian prenyl protein-specific protease

21 January 2018

1 reference

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Disruption of the mouse Rce1 gene results in defective Ras processing and mislocalization of Ras within cells

21 January 2018

1 reference

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High-fidelity gene targeting in embryonic stem cells by using sequence replacement vectors

21 January 2018

1 reference

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Animal models of human genetic diseases

21 January 2018

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21 January 2018

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Deficiency of a protein-repair enzyme results in the accumulation of altered proteins, retardation of growth, and fatal seizures in mice.

21 January 2018

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Consecutive inactivation of both alleles of the pim-1 proto-oncogene by homologous recombination in embryonic stem cells

21 January 2018

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All ras proteins are polyisoprenylated but only some are palmitoylated

21 January 2018

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Fatty acylation of proteins: new insights into membrane targeting of myristoylated and palmitoylated proteins

21 January 2018

1 reference

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Prenylation-dependent association of Ki-Ras with microtubules. Evidence for a role in subcellular trafficking

21 January 2018

1 reference

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Endomembrane trafficking of ras: the CAAX motif targets proteins to the ER and Golgi

21 January 2018

1 reference

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The carboxyl methyltransferase modifying G proteins is a metalloenzyme

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.C000079200

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10747846%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017