129-derived strains of mice are deficient in DNA polymerase iota and have normal immunoglobulin hypermutation (Q28587504)

31 January 2017

title

129-derived strains of mice are deficient in DNA polymerase iota and have normal immunoglobulin hypermutation (English)

1 reference

Polymerase (DNA directed), iota

31 January 2017

main subject

1 reference

GOA release 2020-03-11

author name string

John P. McDonald

1

1 reference

31 January 2017

Ekaterina G. Frank

2

1 reference

31 January 2017

Brian S. Plosky

3

1 reference

31 January 2017

Igor B. Rogozin

4

1 reference

31 January 2017

Chikahide Masutani

5

1 reference

31 January 2017

Fumio Hanaoka

6

1 reference

31 January 2017

Roger Woodgate

7

1 reference

31 January 2017

Patricia J. Gearhart

8

1 reference

31 January 2017

language of work or name

English

0 references

publication date

18 August 2003

1 reference

Journal of Experimental Medicine

31 January 2017

published in

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31 January 2017

volume

198

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31 January 2017

issue

4

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31 January 2017

page(s)

635–643

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DNA polymerase kappa deficiency does not affect somatic hypermutation in mice

31 January 2017

cites work

1 reference

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The role of polymerase eta in somatic hypermutation determined by analysis of mutations in a patient with xeroderma pigmentosum variant

17 March 2017

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AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

17 March 2017

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Error rate and specificity of human and murine DNA polymerase eta

17 March 2017

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Structure of the catalytic core of S. cerevisiae DNA polymerase eta: implications for translesion DNA synthesis

17 March 2017

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Altered nucleotide misinsertion fidelity associated with poliota-dependent replication at the end of a DNA template.

17 March 2017

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DNA polymerase eta is an A-T mutator in somatic hypermutation of immunoglobulin variable genes

17 March 2017

1 reference

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DNA polymerase iota and related rad30-like enzymes

17 March 2017

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Misinsertion and bypass of thymine-thymine dimers by human DNA polymerase iota

17 March 2017

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poliota, a remarkably error-prone human DNA polymerase

17 March 2017

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Complementation of defective translesion synthesis and UV light sensitivity in xeroderma pigmentosum variant cells by human and mouse DNA polymerase eta

17 March 2017

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Mechanisms of accurate translesion synthesis by human DNA polymerase eta

17 March 2017

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Specificity of DNA lesion bypass by the yeast DNA polymerase eta.

17 March 2017

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Fidelity and processivity of Saccharomyces cerevisiae DNA polymerase eta.

17 March 2017

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Novel human and mouse homologs of Saccharomyces cerevisiae DNA polymerase eta

17 March 2017

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The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta

17 March 2017

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Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, Poleta

17 March 2017

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Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting

17 March 2017

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Mismatch repair deficiency interferes with the accumulation of mutations in chronically stimulated B cells and not with the hypermutation process

17 March 2017

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The Y-family of DNA polymerases

17 March 2017

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Eukaryotic polymerases iota and zeta act sequentially to bypass DNA lesions

7 April 2017

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Functions of human DNA polymerases eta, kappa and iota suggested by their properties, including fidelity with undamaged DNA templates.

7 April 2017

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poliota-dependent lesion bypass in vitro

29 September 2017

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Localization of DNA polymerases eta and iota to the replication machinery is tightly co-ordinated in human cells.

29 September 2017

2 references

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29 September 2017

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Induction of somatic hypermutation in immunoglobulin genes is dependent on DNA polymerase iota.

21 January 2018

1 reference

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Correlation of somatic hypermutation specificity and A-T base pair substitution errors by DNA polymerase eta during copying of a mouse immunoglobulin kappa light chain transgene.

29 September 2017

1 reference

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Specialized DNA polymerases, cellular survival, and the genesis of mutations

29 September 2017

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Expression of error-prone polymerases in BL2 cells activated for Ig somatic hypermutation

29 September 2017

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Human DNA polymerase iota promiscuous mismatch extension

29 September 2017

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The expanding polymerase universe

29 September 2017

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5'-Deoxyribose phosphate lyase activity of human DNA polymerase iota in vitro

29 September 2017

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Preferential incorporation of G opposite template T by the low-fidelity human DNA polymerase iota

29 September 2017

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Accuracy of thymine-thymine dimer bypass by Saccharomyces cerevisiae DNA polymerase eta

29 September 2017

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A plethora of lesion-replicating DNA polymerases

29 September 2017

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Radiation and chemical activation of ras oncogenes in different mouse strains.

29 September 2017

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Boundaries of somatic mutation in rearranged immunoglobulin genes: 5' boundary is near the promoter, and 3' boundary is approximately 1 kb from V(D)J gene

29 September 2017

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Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice

29 September 2017

1 reference

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Xeroderma Pigmentosum Variants: Influence of Temperature on Dna Repair

3 June 2018

1 reference

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Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194173

Low fidelity DNA synthesis by human DNA polymerase-eta.

3 June 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030767

Somatic mutation hotspots correlate with DNA polymerase eta error spectrum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030767

Immunology: the roots of antibody diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030767

Fidelity of human DNA polymerase eta

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030767

21 January 2018

Identifiers

DOI

10.1084/JEM.20030767

1 reference

1 reference

1 reference

1 reference