Pbx1 inactivation disrupts pancreas development and in Ipf1-deficient mice promotes diabetes mellitus (Q28588048)

31 January 2017

title

Pbx1 inactivation disrupts pancreas development and in Ipf1-deficient mice promotes diabetes mellitus (English)

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Pre B cell leukemia homeobox 1

31 January 2017

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GOA release 2020-03-11

author name string

Seung K. Kim

1

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31 January 2017

Licia Selleri

2

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31 January 2017

Joon S. Lee

3

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31 January 2017

Andrew Y. Zhang

4

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31 January 2017

Xueying Gu

5

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31 January 2017

Yakop Jacobs

6

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31 January 2017

Michael L. Cleary

7

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31 January 2017

language of work or name

English

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publication date

1 April 2002

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31 January 2017

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31 January 2017

volume

30

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31 January 2017

issue

4

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31 January 2017

page(s)

430–435

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Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor

31 January 2017

cites work

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7 January 2021

A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL

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7 January 2021

Extra specificity from extradenticle: the partnership between HOX and PBX/EXD homeodomain proteins

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7 January 2021

The pancreatic islet factor STF-1 binds cooperatively with Pbx to a regulatory element in the somatostatin promoter: importance of the FPWMK motif and of the homeodomain

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7 January 2021

An endocrine-exocrine switch in the activity of the pancreatic homeodomain protein PDX1 through formation of a trimeric complex with PBX1b and MRG1 (MEIS2).

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7 January 2021

The ParaHox gene cluster is an evolutionary sister of the Hox gene cluster.

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7 January 2021

Insulin-promoter-factor 1 is required for pancreas development in mice

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7 January 2021

Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence

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7 January 2021

The Hox cofactor and proto-oncogene Pbx1 is required for maintenance of definitive hematopoiesis in the fetal liver

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7 January 2021

beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes

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7 January 2021

Early-onset type-II diabetes mellitus (MODY4) linked to IPF1

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7 January 2021

Missense mutations in the insulin promoter factor-1 gene predispose to type 2 diabetes

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7 January 2021

Defective mutations in the insulin promoter factor-1 (IPF-1) gene in late-onset type 2 diabetes mellitus

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7 January 2021

The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas

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7 January 2021

Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cells

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7 January 2021

neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas

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7 January 2021

Epitheliomesenchymal interaction in pancreatic morphogenesis

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7 January 2021

PDX:PBX complexes are required for normal proliferation of pancreatic cells during development

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7 January 2021

TGF-beta plays a key role in morphogenesis of the pancreatic islets of Langerhans by controlling the activity of the matrix metalloproteinase MMP-2

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7 January 2021

Trimeric association of Hox and TALE homeodomain proteins mediates Hoxb2 hindbrain enhancer activity

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7 January 2021

Expression of Pbx1b during mammalian organogenesis

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7 January 2021

Notochord repression of endodermal Sonic hedgehog permits pancreas development

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7 January 2021

Bromodeoxyuridine immunohistochemical determination of the lengths of the cell cycle and the DNA-synthetic phase for an anatomically defined population.

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7 January 2021

Pancreas development is promoted by cyclopamine, a hedgehog signaling inhibitor

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7 January 2021

Identifiers

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31 January 2017

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