Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2 (Q28588417)

GOA release 2020-03-11

author name string

M. Dobles

1

1 reference

31 January 2017

V. Liberal

2

1 reference

31 January 2017

M. L. Scott

3

1 reference

31 January 2017

R. Benezra

4

1 reference

31 January 2017

P. K. Sorger

Sister chromatid separation and chromosome re-duplication are regulated by different mechanisms in response to spindle damage

5

1 reference

31 January 2017

language of work or name

English

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publication date

9 June 2000

1 reference

31 January 2017

1 reference

31 January 2017

101

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31 January 2017

6

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31 January 2017

635–645

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31 January 2017

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Mutations in the essential spindle checkpoint gene bub1 cause chromosome missegregation and fail to block apoptosis in Drosophila

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Spindle checkpoint protein Xmad1 recruits Xmad2 to unattached kinetochores

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The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation

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Budding yeast Bub2 is localized at spindle pole bodies and activates the mitotic checkpoint via a different pathway from Mad2

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The Schizosaccharomyces pombe spindle checkpoint protein mad2p blocks anaphase and genetically interacts with the anaphase-promoting complex

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S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function

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Budding yeast Cdc20: a target of the spindle checkpoint.

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Mitotic forces control a cell-cycle checkpoint

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MAD2 associates with the cyclosome/anaphase-promoting complex and inhibits its activity

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Kinetochore localization of murine Bub1 is required for normal mitotic timing and checkpoint response to spindle damage

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CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis.

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Mad2 transiently associates with an APC/p55Cdc complex during mitosis

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Taxol-induced mitotic block triggers rapid onset of a p53-independent apoptotic pathway.

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Pds1p is required for faithful execution of anaphase in the yeast, Saccharomyces cerevisiae

1 reference

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Identifiers

DOI

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Consolidated OpenCitations Corpus – April 2017

release_r36of76jpvfbned3v3nixrlfye

1252913

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/r36of76jpvfbned3v3nixrlfye

24 November 2022

mapped directly with Wikidata item

1252913

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference