Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice (Q28589323)

GOA release 2020-03-11

author

Erol Fikrig

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Juan Anguita

object named as

Juan Anguita

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Ruslan Medzhitov

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object named as

Ruslan Medzhitov

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31 January 2017

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Richard A. Flavell

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31 January 2017

Lena Alexopoulou

1

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31 January 2017

Venetta Thomas

2

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31 January 2017

Markus Schnare

3

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31 January 2017

Yves Lobet

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31 January 2017

Robert T. Schoen

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31 January 2017

language of work or name

English

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publication date

1 August 2002

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31 January 2017

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31 January 2017

8

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31 January 2017

878–884

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31 January 2017

8

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31 January 2017

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Immunity to Lyme disease: protection, pathology and persistence

21 January 2018

1 reference

Monoclonal antibodies specific for the outer surface protein A (OspA) of Borrelia burgdorferi prevent Lyme borreliosis in severe combined immunodeficiency (scid) mice

21 January 2018

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Efficacy of human Lyme disease vaccine formulations in a mouse model

21 January 2018

1 reference

Vaccination against Lyme disease with recombinant Borrelia burgdorferi outer-surface lipoprotein A with adjuvant. Lyme Disease Vaccine Study Group

21 January 2018

1 reference

The Lyme disease vaccine: conception, development, and implementation

21 January 2018

1 reference

Innate immune recognition: mechanisms and pathways

21 January 2018

1 reference

Roles of Toll-like receptors in innate immune responses

21 January 2018

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Toll-like receptors and innate immunity

21 January 2018

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Toll receptors in innate immunity

21 January 2018

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Toll-like receptors: critical proteins linking innate and acquired immunity

21 January 2018

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Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

21 January 2018

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Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

21 January 2018

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The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

21 January 2018

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A Toll-like receptor recognizes bacterial DNA

21 January 2018

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Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components

21 January 2018

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Toll-like receptor-2 mediates mycobacteria-induced proinflammatory signaling in macrophages.

21 January 2018

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Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors

21 January 2018

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Discrimination of bacterial lipoproteins by Toll-like receptor 6

21 January 2018

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OspA lipoprotein of Borrelia burgdorferi is a mucosal immunogen and adjuvant.

21 January 2018

1 reference

The instructive role of innate immunity in the acquired immune response

21 January 2018

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Cutting edge: functional interactions between toll-like receptor (TLR) 2 and TLR1 or TLR6 in response to phenol-soluble modulin

21 January 2018

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The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors

21 January 2018

1 reference

Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide

21 January 2018

1 reference

Activation of toll-like receptors by microbial lipoproteins: role in host defense

21 January 2018

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Coinfection with Borrelia burgdorferi and the agent of human granulocytic ehrlichiosis alters murine immune responses, pathogen burden, and severity of Lyme arthritis

21 January 2018

1 reference

21 January 2018

1 reference

7 January 2021

Carditis in Lyme disease susceptible and resistant strains of laboratory mice infected with Borrelia burgdorferi.

1 reference

7 January 2021

Protection of mice against the Lyme disease agent by immunizing with recombinant OspA

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7 January 2021

Toll-like receptors control activation of adaptive immune responses

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7 January 2021

Sera from patients with chronic Lyme disease protect mice from Lyme borreliosis

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7 January 2021

Toll-like receptor 2 is required for innate, but not acquired, host defense to Borrelia burgdorferi

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7 January 2021