Mouse NRH:quinone oxidoreductase (NQO2): cloning of cDNA and gene- and tissue-specific expression (Q28589848)

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

GOA release 2020-03-11

author name string

D. J. Long

series ordinal

1

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31 January 2017

A. K. Jaiswal

series ordinal

2

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31 January 2017

language of work or name

English

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publication date

11 July 2000

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31 January 2017

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31 January 2017

252

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31 January 2017

1-2

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31 January 2017

107–117

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31 January 2017

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Human FAD-dependent NAD(P)H diaphorase

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Human NAD(P)H:quinone oxidoreductase (NQO1) gene structure and induction by dioxin

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Antioxidant response element

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Nucleotide and deduced amino acid sequence of a human cDNA (NQO2) corresponding to a second member of the NAD(P)H:quinone oxidoreductase gene family. Extensive polymorphism at the NQO2 gene locus on chromosome 6

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Localization of human NQO1 gene to chromosome 16q22 and NQO2-6p25 and associated polymorphisms

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NAD(P)H:quinone oxidoreductase1 (DT diaphorase) specifically prevents the formation of benzo[a]pyrene quinone-DNA adducts generated by cytochrome P4501A1 and P450 reductase

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Formation of benzo[a]pyrene-3,6-quinol mono- and diglucuronides in rat liver microsomes.

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Quinone chemistry and toxicity

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Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated expression and coordinated induction of genes encoding detoxifying enzymes

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Disruption of the DT diaphorase (NQO1) gene in mice leads to increased menadione toxicity.

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The human dioxin-inducible NAD(P)H: quinone oxidoreductase cDNA-encoded protein expressed in COS-1 cells is identical to diaphorase 4.

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Chemoprotection against cancer by phase 2 enzyme induction

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Catalytic properties of NAD(P)H:quinone oxidoreductase-2 (NQO2), a dihydronicotinamide riboside dependent oxidoreductase

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Unexpected genetic and structural relationships of a long-forgotten flavoenzyme to NAD(P)H:quinone reductase (DT-diaphorase)

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