NPC2 is expressed in human and murine liver and secreted into bile: potential implications for body cholesterol homeostasis (Q28590002)

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14 January 2020

title

NPC2 is expressed in human and murine liver and secreted into bile: potential implications for body cholesterol homeostasis (English)

2 references

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1

1 reference

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author name string

Ludwig Amigo

2

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María José Retamal

3

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María Gabriela Morales

4

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Juan Francisco Miquel

5

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Attilio Rigotti

6

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Silvana Zanlungo

7

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language of work or name

English

0 references

publication date

1 January 2006

2 references

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volume

43

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issue

1

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page(s)

126-133

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The pathophysiology and mechanisms of NP-C disease.

14 January 2020

cites work

1 reference

Lipid and cholesterol trafficking in NPC.

21 January 2018

1 reference

A porcine homolog of the major secretory protein of human epididymis, HE1, specifically binds cholesterol

21 January 2018

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Relevance of Niemann-Pick type C1 protein expression in controlling plasma cholesterol and biliary lipid secretion in mice

21 January 2018

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Structure and function of the NPC2 protein

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Molecular, anatomical, and biochemical events associated with neurodegeneration in mice with Niemann-Pick type C disease

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Hepatic overexpression of caveolins increases bile salt secretion in mice

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Effects of colchicine and vinblastine on output of proteins into bile

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Abnormal secretion of proteins into bile from colchicine-treated isolated perfused rat livers

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Effect of chloroquine on biliary lipid and lysosomal enzyme output in the isolated perfused rat liver at low bile salt output rates

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Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis

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7 January 2021

Identification of HE1 as the second gene of Niemann-Pick C disease

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7 January 2021

Murine model of Niemann-Pick C disease: mutation in a cholesterol homeostasis gene.

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7 January 2021

Structure of a cholesterol-binding protein deficient in Niemann-Pick type C2 disease

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7 January 2021

The integrity of a cholesterol-binding pocket in Niemann-Pick C2 protein is necessary to control lysosome cholesterol levels.

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7 January 2021

The Niemann-Pick C1 protein resides in a vesicular compartment linked to retrograde transport of multiple lysosomal cargo

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Niemann-pick type C1 (NPC1) overexpression alters cellular cholesterol homeostasis

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7 January 2021

NPC1 and NPC2 Regulate Cellular Cholesterol Homeostasis through Generation of Low Density Lipoprotein Cholesterol-derived Oxysterols

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Cholesterol balance and metabolism in mice with loss of function of Niemann-Pick C protein.

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7 January 2021

Cholesterol accumulation in tissues of the Niemann-pick type C mouse is determined by the rate of lipoprotein-cholesterol uptake through the coated-pit pathway in each organ

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Neuronal localization and association of Niemann Pick C2 protein (HE1/NPC2) with the postsynaptic density

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7 January 2021

Secretion of sterols and the NPC2 protein from primary astrocytes

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Hepatic cholesterol transport from plasma into bile: implications for gallstone disease

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Genetic epidemiology of cholesterol cholelithiasis among Chilean Hispanics, Amerindians, and Maoris.

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Prevalence and ethnic differences in gallbladder disease in the United States

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A simplified system for generating recombinant adenoviruses

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Sterol carrier protein 2 gene transfer changes lipid metabolism and enterohepatic sterol circulation in mice

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7 January 2021

Stallion epididymal fluid proteome: qualitative and quantitative characterization; secretion and dynamic changes of major proteins

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7 January 2021

A method for the quantitative recovery of protein in dilute solution in the presence of detergents and lipids

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7 January 2021

Cholesterol saturation, not proteins or cholecystitis, is critical for crystal formation in human gallbladder bile.

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7 January 2021

Increased activity in the biliary Con A-binding fraction accounts for the difference in crystallization behavior in bile from Chilean gallstone patients compared with Dutch gallstone patients

1 reference

7 January 2021

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1 reference

7 January 2021

Defective endocytic trafficking of NPC1 and NPC2 underlying infantile Niemann-Pick type C disease

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7 January 2021

Molecular cloning and characterization of HE1, a major secretory protein of the human epididymis

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7 January 2021

Genetic evidence for nonredundant functional cooperativity between NPC1 and NPC2 in lipid transport

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7 January 2021

Multidrug permeases and subcellular cholesterol transport

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7 January 2021

Role of cholesterol in sperm capacitation

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7 January 2021

Primary structure of EPV20, a secretory glycoprotein containing a previously uncharacterized type of domain.

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7 January 2021

Effects of infection and inflammation on lipid and lipoprotein metabolism: mechanisms and consequences to the host

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7 January 2021

The molecular and metabolic basis of biliary cholesterol secretion and gallstone disease.

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7 January 2021

Cholesterol nucleation-influencing activity in T-tube bile

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7 January 2021

Isolation and partial characterization of cholesterol pronucleating hydrophobic glycoproteins associated to native biliary vesicles

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7 January 2021

Apolipoprotein A-I in bile inhibits cholesterol crystallization and modifies transcellular lipid transfer through cultured human gall-bladder epithelial cells

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7 January 2021

Concanavalin A-binding cholesterol crystallization inhibiting and promoting activity in bile from patients with Crohn's disease compared to patients with ulcerative colitis

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7 January 2021

Role of biliary proteins and non-protein factors in kinetics of cholesterol crystallisation and gallstone growth.

1 reference

7 January 2021

Identifiers

2 references

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2 references

31 January 2017