Loss of pleckstrin defines a novel pathway for PKC-mediated exocytosis (Q28590349)

4

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author name string

Lurong Lian

1

1 reference

31 January 2017

Yanfeng Wang

2

1 reference

31 January 2017

Matthew Flick

3

1 reference

31 January 2017

Edward W. Scott

5

1 reference

31 January 2017

Jay Degen

6

1 reference

31 January 2017

Charles S. Abrams

Structural analysis of the carboxy terminal PH domain of pleckstrin bound to D-myo-inositol 1,2,3,5,6-pentakisphosphate

8

1 reference

31 January 2017

language of work or name

English

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publication date

9 April 2009

1 reference

31 January 2017

1 reference

31 January 2017

113

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31 January 2017

15

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31 January 2017

3577–3584

1 reference

31 January 2017

1 reference

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PI3K regulates pleckstrin-2 in T-cell cytoskeletal reorganization.

17 March 2017

1 reference

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DEP-domain-mediated regulation of GPCR signaling responses.

17 March 2017

1 reference

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SMART 5: domains in the context of genomes and networks

17 March 2017

1 reference

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PI 3-kinase p110beta: a new target for antithrombotic therapy

17 March 2017

1 reference

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Structure and phosphatidylinositol-(3,4)-bisphosphate binding of the C-terminal PH domain of human pleckstrin

17 March 2017

1 reference

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Phosphorylated pleckstrin induces cell spreading via an integrin-dependent pathway

17 March 2017

1 reference

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Pleckstrin induces cytoskeletal reorganization via a Rac-dependent pathway

17 March 2017

1 reference

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Pleckstrin 2, a widely expressed paralog of pleckstrin involved in actin rearrangement

17 March 2017

1 reference

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Human platelets contain SNARE proteins and a Sec1p homologue that interacts with syntaxin 4 and is phosphorylated after thrombin activation: implications for platelet secretion

17 March 2017

1 reference

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Pleckstrin associates with plasma membranes and induces the formation of membrane projections: requirements for phosphorylation and the NH2-terminal PH domain

17 March 2017

1 reference

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Phosphorylation of platelet pleckstrin activates inositol polyphosphate 5-phosphatase I

17 March 2017

1 reference

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A putative modular domain present in diverse signaling proteins

17 March 2017

1 reference

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Pleckstrin domain homology

17 March 2017

1 reference

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The PH domain: a common piece in the structural patchwork of signalling proteins

17 March 2017

1 reference

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Crystal structure at 2.2 A resolution of the pleckstrin homology domain from human dynamin

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668855

Pleckstrin inhibits phosphoinositide hydrolysis initiated by G-protein-coupled and growth factor receptors. A role for pleckstrin's PH domains

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668855

Protein kinase C regulates pleckstrin by phosphorylation of sites adjacent to the N-terminal pleckstrin homology domain

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668855

Molecular analysis of pleckstrin: the major protein kinase C substrate of platelets

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668855

MARCKS is an actin filament crosslinking protein regulated by protein kinase C and calcium-calmodulin

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668855

Membrane recognition by phospholipid-binding domains

17 March 2017

1 reference

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Endobrevin/VAMP-8 is the primary v-SNARE for the platelet release reaction

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668855

Electrostatic sequestration of PIP2 on phospholipid membranes by basic/aromatic regions of proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668855

Pleckstrin homology domains and the cytoskeleton

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668855

GAP43, MARCKS, and CAP23 modulate PI(4,5)P(2) at plasmalemmal rafts, and regulate cell cortex actin dynamics through a common mechanism

29 September 2017

1 reference

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Expression of the protein kinase C substrate pleckstrin in macrophages: association with phagosomal membranes.

29 September 2017

1 reference

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Cytoskeletal reorganization by G protein-coupled receptors is dependent on phosphoinositide 3-kinase gamma, a Rac guanosine exchange factor, and Rac.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668855

Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668855

Influence of a microtubule stabilizing agent on platelet structural physiology

29 September 2017

1 reference

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Effects of a microtubule stabilizing agent on the response of platelets to vincristine

29 September 2017

1 reference

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Molecular cloning and expression of the major protein kinase C substrate of platelets

29 September 2017

1 reference

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Effects of collagen, ionophore A23187 and prostaglandin E1 on the phosphorylation of specific proteins in blood platelets

29 September 2017

1 reference

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Relationship between phosphorylation of blood platelet proteins and secretion of platelet granule constituents I. Effects of different aggregating agents

29 September 2017

1 reference

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The relative role of PLCbeta and PI3Kgamma in platelet activation

29 September 2017

1 reference

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A site of interaction between pleckstrin's PH domains and G beta gamma.

3 June 2018

1 reference

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Pleckstrin's repeat performance: a novel domain in G-protein signaling?

3 June 2018

1 reference

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The binding site for the beta gamma subunits of heterotrimeric G proteins on the beta-adrenergic receptor kinase

3 June 2018

1 reference

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Redistribution of alpha-granules and their contents in thrombin-stimulated platelets

3 June 2018

1 reference

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The actin cytoskeleton differentially regulates platelet alpha-granule and dense-granule secretion

3 June 2018

1 reference

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Membrane trafficking: dual-key strategy

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668855

Subcellular distribution of 3 functional platelet SNARE proteins: human cellubrevin, SNAP-23, and syntaxin 2.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668855

Resistance to thromboembolism in PI3Kgamma-deficient mice.

27 November 2018

1 reference

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Protein kinase C-catalyzed phosphorylation of an inhibitory phosphoprotein of myosin phosphatase is involved in human platelet secretion

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668855

Recombinant scinderin, an F-actin severing protein, increases calcium-induced release of serotonin from permeabilized platelets, an effect blocked by two scinderin-derived actin-binding peptides and phosphatidylinositol 4,5-bisphosphate

27 November 2018

1 reference

12 December 2020

Proteins of the exocytotic core complex mediate platelet alpha-granule secretion. Roles of vesicle-associated membrane protein, SNAP-23, and syntaxin 4

1 reference

12 December 2020

Agonist-induced regulation of myosin phosphatase activity in human platelets through activation of Rho-kinase

1 reference

12 December 2020

Phosphopleckstrin inhibits gbetagamma-activable platelet phosphatidylinositol-4,5-bisphosphate 3-kinase

1 reference

12 December 2020

Phosphorylation and subcellular redistribution of pleckstrin in human neutrophils

1 reference

12 December 2020

Platelet secretion induced by phorbol esters stimulation is mediated through phosphorylation of MARCKS: a MARCKS-derived peptide blocks MARCKS phosphorylation and serotonin release without affecting pleckstrin phosphorylation

1 reference

12 December 2020

Differential effects of cytochalasin B on platelet release, aggregation and contractility: evidence against a contractile mechanism for the release of platelet granular contents

1 reference

12 December 2020

Purification and characterization of the 47,000-dalton protein phosphorylated during degranulation of human platelets

1 reference

12 December 2020

Protein kinase C phosphorylates human platelet inositol trisphosphate 5'-phosphomonoesterase, increasing the phosphatase activity

1 reference

12 December 2020

Cytochalasin E enhances the protein kinase C-dependent process of secretion

1 reference

12 December 2020

P47 phosphoprotein of blood platelets (pleckstrin) is a major target for phorbol ester-induced protein phosphorylation in intact platelets, granulocytes, lymphocytes, monocytes and cultured leukaemic cells: absence of P47 in non-haematopoietic cells

1 reference

12 December 2020