ADAM8: a new therapeutic target for asthma (Q28590394)

31 January 2017

1 reference

Europe PubMed Central

title

ADAM8: a new therapeutic target for asthma (English)

1 reference

A disintegrin and metallopeptidase domain 8

31 January 2017

0 references

1 reference

GOA release 2020-03-11

author name string

Martin D. Knolle

series ordinal

1

1 reference

31 January 2017

Caroline A. Owen

series ordinal

2

1 reference

31 January 2017

language of work or name

English

0 references

publication date

1 May 2009

1 reference

Expert Opinion on Therapeutic Targets

31 January 2017

published in

1 reference

31 January 2017

volume

13

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31 January 2017

issue

5

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31 January 2017

page(s)

523–540

1 reference

ADAM8 is selectively up-regulated in endothelial cells and is associated with angiogenesis after spinal cord injury in adult mice

31 January 2017

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Increased expression of ADAM33 and ADAM8 with disease progression in asthma

17 March 2017

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17 March 2017

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ADAM8 as a novel serological and histochemical marker for lung cancer

17 March 2017

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17 March 2017

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ADAM28 is activated by MMP-7 (matrilysin-1) and cleaves insulin-like growth factor binding protein-3

17 March 2017

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Ectodomain shedding of the neural recognition molecule CHL1 by the metalloprotease-disintegrin ADAM8 promotes neurite outgrowth and suppresses neuronal cell death

17 March 2017

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The splicing and fate of ADAM33 transcripts in primary human airways fibroblasts

17 March 2017

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Association of a disintegrin and metalloprotease 33 (ADAM33) gene with asthma in ethnically diverse populations

17 March 2017

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The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion

17 March 2017

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ADAM-9 is an insulin-like growth factor binding protein-5 protease produced and secreted by human osteoblasts

17 March 2017

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The metalloprotease disintegrin ADAM8. Processing by autocatalysis is required for proteolytic activity and cell adhesion

17 March 2017

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17 March 2017

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The enzymatic activity of ADAM8 and ADAM9 is not regulated by TIMPs

17 March 2017

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Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness

17 March 2017

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Platelet-activating factor receptor and ADAM10 mediate responses to Staphylococcus aureus in epithelial cells

17 March 2017

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Phosphorylation-dependent interactions between ADAM15 cytoplasmic domain and Src family protein-tyrosine kinases

17 March 2017

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ADAM8: a novel osteoclast stimulating factor

17 March 2017

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Tumor necrosis factor alpha induces a metalloprotease-disintegrin, ADAM8 (CD 156): implications for neuron-glia interactions during neurodegeneration

17 March 2017

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Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis

17 March 2017

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Interaction of the metalloprotease disintegrins MDC9 and MDC15 with two SH3 domain-containing proteins, endophilin I and SH3PX1

17 March 2017

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Chymase cleavage of stem cell factor yields a bioactive, soluble product

17 March 2017

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17 March 2017

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Hydrolysis of a broad spectrum of extracellular matrix proteins by human macrophage elastase

17 March 2017

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17 March 2017

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17 March 2017

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17 March 2017

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The global burden of asthma: executive summary of the GINA Dissemination Committee report

17 March 2017

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7 April 2017

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The cytokine network in asthma and chronic obstructive pulmonary disease

29 September 2017

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TH17 cells mediate steroid-resistant airway inflammation and airway hyperresponsiveness in mice

29 September 2017

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29 September 2017

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Airway lipoxin A4 generation and lipoxin A4 receptor expression are decreased in severe asthma

29 September 2017

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Resolvin E1 regulates interleukin 23, interferon-gamma and lipoxin A4 to promote the resolution of allergic airway inflammation

29 September 2017

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TNF-alpha-induced up-regulation of intercellular adhesion molecule-1 is regulated by a Rac-ROS-dependent cascade in human airway epithelial cells

29 September 2017

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Leukocyte cell surface proteinases: regulation of expression, functions, and mechanisms of surface localization

29 September 2017

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Immunologic and inflammatory mechanisms that drive asthma progression to remodeling

29 September 2017

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Lipoxin A4 stable analogs reduce allergic airway responses via mechanisms distinct from CysLT1 receptor antagonism

29 September 2017

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Mice lacking neutrophil elastase are resistant to bleomycin-induced pulmonary fibrosis

29 September 2017

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Protectin D1 is generated in asthma and dampens airway inflammation and hyperresponsiveness

29 September 2017

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Expression of ADAMs and their inhibitors in sputum from patients with asthma

29 September 2017

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Metalloprotease-induced ectodomain shedding of neural cell adhesion molecule (NCAM).

29 September 2017

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ADAM33 is not essential for growth and development and does not modulate allergic asthma in mice

29 September 2017

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ADAM33 haplotypes are associated with asthma in a large Australian population

29 September 2017

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Metalloproteinase disintegrins ADAM8 and ADAM19 are highly regulated in human primary brain tumors and their expression levels and activities are associated with invasiveness

29 September 2017

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Expression of a disintegrin and metalloprotease (ADAM and ADAMTS) enzymes in human non-small-cell lung carcinomas (NSCLC).

29 September 2017

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Stem cell factor expression, mast cells and inflammation in asthma

29 September 2017

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ADAM33: a newly identified protease involved in airway remodelling

29 September 2017

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Src and Syk kinases: key regulators of phagocytic cell activation.

29 September 2017

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29 September 2017

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Matrix metalloproteinases as modulators of inflammation and innate immunity

29 September 2017

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The alveolar macrophage: the forgotten cell in asthma

29 September 2017

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Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands

29 September 2017

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Asthma is associated with single-nucleotide polymorphisms in ADAM33.

29 September 2017

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Role of regulatory T cells in allergy and asthma

29 September 2017

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Stem cell factor: a hemopoietic cytokine with important targets in asthma.

29 September 2017

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Tumor necrosis factor alpha-converting enzyme mediates MUC5AC mucin expression in cultured human airway epithelial cells

29 September 2017

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Tobacco Smoke-induced Lung Cell Proliferation Mediated by Tumor Necrosis Factor α-converting Enzyme and Amphiregulin

29 September 2017

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Airway remodeling in asthma: new insights

29 September 2017

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ADAM-33 surfaces as an asthma gene

29 September 2017

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Persistent asthma: disease control, resource utilisation and direct costs

29 September 2017

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The role of ADAM 15 in glomerular mesangial cell migration

29 September 2017

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Expression of FcgammaRIII (CD16) on human peripheral blood eosinophils increases in allergic conditions

29 September 2017

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Decreased allergic lung inflammatory cell egression and increased susceptibility to asphyxiation in MMP2-deficiency

29 September 2017

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Regulation of protrusive and contractile cell-matrix contacts.

29 September 2017

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Tumor necrosis factor-alpha-converting enzyme mediates the inducible cleavage of fractalkine

29 September 2017

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Human peripheral blood eosinophils express stem cell factor

29 September 2017

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Metalloprotease-disintegrin ADAM 12 binds to the SH3 domain of Src and activates Src tyrosine kinase in C2C12 cells

29 September 2017

1 reference

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Involvement of the epidermal growth factor receptor in epithelial repair in asthma

29 September 2017

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Airway neutrophils and interleukin-17.

29 September 2017

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Stem cell factor-induced airway hyperreactivity in allergic and normal mice

29 September 2017

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Cell type-specific glycoforms of Fc gamma RIIIa (CD16): differential ligand binding.

29 September 2017

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Mouse CD23 regulates monocyte activation through an interaction with the adhesion molecule CD11b/CD18.

29 September 2017

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Structure of the murine CD156 gene, characterization of its promoter, and chromosomal location

29 September 2017

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Airway epithelial cells produce stem cell factor

29 September 2017

1 reference

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Molecular cloning of cDNA encoding MS2 antigen, a novel cell surface antigen strongly expressed in murine monocytic lineage

29 September 2017

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Surface expression of Fc gamma receptor III (CD16) on chemoattractant-stimulated neutrophils is determined by both surface shedding and translocation from intracellular storage compartments

29 September 2017

1 reference

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Regulated expression of ADAM8 (a disintegrin and metalloprotease domain 8) in the mouse ovary: evidence for a regulatory role of luteinizing hormone, progesterone receptor, and epidermal growth factor-like growth factors

29 September 2017

1 reference

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Airway smooth muscle cell proliferation is increased in asthma

3 June 2018

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Regulation of low affinity IgE receptor (CD23) expression on mononuclear phagocytes in normal and asthmatic subjects

3 June 2018

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CD21 is a ligand for CD23 and regulates IgE production

3 June 2018

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Release of transforming growth factor-beta 1 from the pericellular matrix of cultured fibroblasts and fibrosarcoma cells by plasmin and thrombin

3 June 2018

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Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity

3 June 2018

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Lung dendritic cells: targets for therapy in allergic disease

21 January 2018

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Mild and moderate asthma is associated with airway goblet cell hyperplasia and abnormalities in mucin gene expression

21 January 2018

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Markers of eosinophilic inflammation and tissue re-modelling in children before clinically diagnosed bronchial asthma

21 January 2018

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Asthmatic bronchial epithelium is more susceptible to oxidant-induced apoptosis.

21 January 2018

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Matrix metalloproteinase-8 deficiency promotes granulocytic allergen-induced airway inflammation

21 January 2018

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Reduced peribronchial fibrosis in allergen-challenged MMP-9-deficient mice.

21 January 2018

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Differential inhibition of thrombin- and EGF-stimulated human cultured airway smooth muscle proliferation by glucocorticoids.

21 January 2018

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Identification of candidate substrates for ectodomain shedding by the metalloprotease-disintegrin ADAM8.

21 January 2018

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Epigenetic mechanisms silence a disintegrin and metalloprotease 33 expression in bronchial epithelial cells

21 January 2018

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Expression and regulation of a disintegrin and metalloproteinase (ADAM) 8 in experimental asthma

21 January 2018

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Elevated soluble ADAM8 in bronchoalveolar lavage fluid in patients with eosinophilic pneumonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902889788

ADAM33 polymorphisms and phenotype associations in childhood asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902889788

ADAM33 is not associated with asthma in Puerto Rican or Mexican populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902889788

CD156 transgenic mice. Different responses between inflammatory types

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902889788

Role of ADAM8 in experimental asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902889788

The soluble form of a disintegrin and metalloprotease 33 promotes angiogenesis: implications for airway remodeling in asthma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902889788

Evidence of a role of tumor necrosis factor alpha in refractory asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902889788

Adenovirus expressing interleukin-1 receptor antagonist alleviates allergic airway inflammation in a murine model of asthma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902889788

Role of Metalloproteases in the Release of the IL-1 type II Decoy Receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902889788

Blood monocytes of untreated asthmatics exhibit some features of tissue macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902889788

Endocytosis and recycling of the complex between CD23 and HLA-DR in human B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902889788

The structure of human CD23 and its interactions with IgE and CD21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902889788

Metalloproteinases mediate mucin 5AC expression by epidermal growth factor receptor activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902889788

Activation of latent transforming growth factor beta1 by stromelysin 1 in extracts of growth plate chondrocyte-derived matrix vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902889788

Elevated levels of the IGF-binding protein protease MMP-1 in asthmatic airway smooth muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902889788

ADAM33 polymorphism: association with bronchial hyper-responsiveness in Korean asthmatics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902889788

The disintegrin domain of ADAM 8 enhances protection against rat experimental autoimmune encephalomyelitis, neuritis and uveitis by a polyvalent autoantigen vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902889788

Modification of the transcriptomic response to renal ischemia/reperfusion injury by lipoxin analog.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902889788

ADAM8 expression in prostate cancer is associated with parameters of unfavorable prognosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902889788

Expression of ADAMs ("a disintegrin and metalloprotease") in the human lung

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784995

National Ambulatory Medical Care Survey: 2006 summary.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784995

Autoactivation of human ADAM8: a novel pre-processing step is required for catalytic activity

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784995

SCF-induced airway hyperreactivity is dependent on leukotriene production

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784995

IL-13 induces mucin production by stimulating epidermal growth factor receptors and by activating neutrophils.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784995

Humoral response suppression observed with CD23 transgenics.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784995

Effects of growth factors and extracellular matrix on survival of human airway smooth muscle cells

27 November 2018

1 reference

12 December 2020

Marked goblet cell hyperplasia with mucus accumulation in the airways of patients who died of severe acute asthma attack

1 reference

12 December 2020

Neutrophil apoptosis is associated with a reduction in CD16 (Fc gamma RIII) expression

1 reference

12 December 2020

L-selectin and very late antigen-4 integrin promote eosinophil rolling at physiological shear rates in vivo

1 reference

12 December 2020

Leukotriene D4 facilitates airway smooth muscle cell proliferation via modulation of the IGF axis

1 reference

12 December 2020

Interleukin-4 and soluble CD23 serum levels in asthmatic atopic children

1 reference

12 December 2020

A metalloproteinase inhibitor blocks the shedding of soluble cytokine receptors and processing of transmembrane cytokine precursors in human monocytic cells

1 reference

12 December 2020

Expression of CD23 antigen and its ligands in children with intrinsic and extrinsic asthma

1 reference

12 December 2020

The metallo-disintegrin ADAM10 (MADM) from bovine kidney has type IV collagenase activity in vitro

1 reference

12 December 2020

CD23 and allergic pulmonary inflammation: potential role as an inhibitor

1 reference

12 December 2020

Inhibition of myofibroblast apoptosis by transforming growth factor beta(1)

1 reference

12 December 2020

alpha9beta1 integrin is expressed on human neutrophils and contributes to neutrophil migration through human lung and synovial fibroblast barriers

1 reference

12 December 2020

Airway inflammation and altered alveolar macrophage phenotype pattern after repeated low-dose allergen exposure of atopic asthmatic subjects

1 reference

12 December 2020

Autocrine production of matrix metalloproteinase-2 is required for human airway smooth muscle proliferation

1 reference

12 December 2020

Elevated mid-trimester amniotic fluid ADAM-8 concentrations as a potential risk factor for preterm delivery

1 reference

12 December 2020

ADAM33 polymorphisms are associated with asthma susceptibility in a Japanese population

1 reference

12 December 2020

ADAM10 is a principal 'sheddase' of the low-affinity immunoglobulin E receptor CD23

1 reference

12 December 2020

The detection of ADAM8 protein on cells of the human immune system and the demonstration of its expression on peripheral blood B cells, dendritic cells and monocyte subsets

1 reference

12 December 2020

ADAM-12 (meltrin alpha) is involved in chondrocyte proliferation via cleavage of insulin-like growth factor binding protein 5 in osteoarthritic cartilage

1 reference

12 December 2020

Early thickening of the reticular basement membrane in children with difficult asthma

1 reference

12 December 2020

The CX3C chemokine fractalkine in allergic asthma and rhinitis

1 reference

12 December 2020

Matrix metalloproteinase-9 deficiency results in enhanced allergen-induced airway inflammation

1 reference

12 December 2020

Myofibroblasts and subepithelial fibrosis in bronchial asthma

1 reference

12 December 2020

10.1517/14728220902889788

Identifiers

DOI

1 reference

31 January 2017

0 references

1 reference