DNA binding and transcriptional activation by a PDX1.PBX1b.MEIS2b trimer and cooperation with a pancreas-specific basic helix-loop-helix complex (Q28591464)

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English	DNA binding and transcriptional activation by a PDX1.PBX1b.MEIS2b trimer and cooperation with a pancreas-specific basic helix-loop-helix complex	scientific journal article

Statements

scholarly article

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31 January 2017

DNA binding and transcriptional activation by a PDX1.PBX1b.MEIS2b trimer and cooperation with a pancreas-specific basic helix-loop-helix complex (English)

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31 January 2017

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PDX1-PBX1b-MRG1 complex

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Gene Ontology release 2020-05-02

Gene Ontology ID

Meis homeobox 2

1 reference

GOA release 2020-03-11

Pancreas specific transcription factor, 1a

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GOA release 2020-03-11

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based on heuristic

inferred from title

author name string

Y. Liu

1

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31 January 2017

R. J. MacDonald

2

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31 January 2017

G. H. Swift

3

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31 January 2017

language of work or name

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publication date

25 May 2001

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31 January 2017

Journal of Biological Chemistry

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31 January 2017

276

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31 January 2017

21

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31 January 2017

17985–17993

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31 January 2017

Hox genes in evolution: protein surfaces and paralog groups

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

Hox genes in vertebrate development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

Homeobox genes: their function in Drosophila segmentation and pattern formation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

Analysis of TALE superclass homeobox genes (MEIS, PBC, KNOX, Iroquois, TGIF) reveals a novel domain conserved between plants and animals

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

New motif in PBX genes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

Meis1 and pKnox1 bind DNA cooperatively with Pbx1 utilizing an interaction surface disrupted in oncoprotein E2a-Pbx1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

The pancreatic islet factor STF-1 binds cooperatively with Pbx to a regulatory element in the somatostatin promoter: importance of the FPWMK motif and of the homeodomain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

An endocrine-exocrine switch in the activity of the pancreatic homeodomain protein PDX1 through formation of a trimeric complex with PBX1b and MRG1 (MEIS2).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

The ParaHox gene cluster is an evolutionary sister of the Hox gene cluster.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

Insulin-promoter-factor 1 is required for pancreas development in mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

PDX:PBX complexes are required for normal proliferation of pancreatic cells during development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

Insulin expression in pancreatic islet cells relies on cooperative interactions between the helix loop helix factor E47 and the homeobox factor STF-1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

The human glucokinase gene beta-cell-type promoter: an essential role of insulin promoter factor 1/PDX-1 in its activation in HIT-T15 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

Induction of insulin and islet amyloid polypeptide production in pancreatic islet glucagonoma cells by insulin promoter factor 1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

Identification of cis- and trans-active factors regulating human islet amyloid polypeptide gene expression in pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

Transcriptional activation of the GLUT2 gene by the IPF-1/STF-1/IDX-1 homeobox factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

A single element of the elastase I enhancer is sufficient to direct transcription selectively to the pancreas and gut.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

Differential requirements for cell-specific elastase I enhancer domains in transfected cells and transgenic mice.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

Cooperation between elements of an organ-specific transcriptional enhancer in animals

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

Identification of a cell-specific DNA-binding activity that interacts with a transcriptional activator of genes expressed in the acinar pancreas

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

Pancreatic neoplasia induced by SV40 T-antigen expression in acinar cells of transgenic mice.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

Beta-cell lines derived from transgenic mice expressing a hybrid insulin gene-oncogene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

Multipotential phenotypic expression of genes encoding peptide hormones in rat insulinoma cell lines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

A structural model for a homeotic protein-extradenticle-DNA complex accounts for the choice of HOX protein in the heterodimer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

Meis2, a novel mouse Pbx-related homeobox gene induced by retinoic acid during differentiation of P19 embryonal carcinoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

Functional characterization of the transactivation properties of the PDX-1 homeodomain protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

Prep1, a novel functional partner of Pbx proteins.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

The novel homeoprotein Prep1 modulates Pbx-Hox protein cooperativity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

Meis proteins are major in vivo DNA binding partners for wild-type but not chimeric Pbx proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

Structural determinants within Pbx1 that mediate cooperative DNA binding with pentapeptide-containing Hox proteins: proposal for a model of a Pbx1-Hox-DNA complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

Structure of a HoxB1-Pbx1 heterodimer bound to DNA: role of the hexapeptide and a fourth homeodomain helix in complex formation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

Pbx raises the DNA binding specificity but not the selectivity of antennapedia Hox proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

Trimeric association of Hox and TALE homeodomain proteins mediates Hoxb2 hindbrain enhancer activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

p21 is a transcriptional target of HOXA10 in differentiating myelomonocytic cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

Selective repression of transcriptional activators by Pbx1 does not require the homeodomain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

Functional dissection of a transcriptionally active, target-specific Hox-Pbx complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

The homeodomain of PDX-1 mediates multiple protein-protein interactions in the formation of a transcriptional activation complex on the insulin promoter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

A conserved motif N-terminal to the DNA-binding domains of myogenic bHLH transcription factors mediates cooperative DNA binding with pbx-Meis1/Prep1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100678200

21 January 2018

Identifiers

10.1074/JBC.M100678200

1 reference

31 January 2017

1 reference

31 January 2017

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