Defects in nuclear structure and function promote dilated cardiomyopathy in lamin A/C-deficient mice (Q28591672)

2

1 reference

31 January 2017

Aisling C. McMahon

3

1 reference

31 January 2017

Ju Chiat Tan

4

1 reference

31 January 2017

Suchitra Chandar

5

1 reference

31 January 2017

Dilesh Jogia

6

1 reference

31 January 2017

Scott H. Kesteven

7

1 reference

31 January 2017

Jan Michalicek

8

1 reference

31 January 2017

Robyn Otway

9

1 reference

31 January 2017

Fons Verheyen

10

1 reference

31 January 2017

Stephen Rainer

11

1 reference

31 January 2017

Colin L. Stewart

12

1 reference

31 January 2017

David Martin

13

1 reference

31 January 2017

Michael P. Feneley

14

1 reference

31 January 2017

Diane Fatkin

Journal of Clinical Investigation

15

1 reference

31 January 2017

language of work or name

English

0 references

publication date

1 February 2004

1 reference

31 January 2017

1 reference

31 January 2017

113

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31 January 2017

357–369

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31 January 2017

3

1 reference

31 January 2017

describes a project that uses

ImageQuant

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC324538/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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A novel interaction between lamin A and SREBP1: implications for partial lipodystrophy and other laminopathies

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Myne-1, a spectrin repeat transmembrane protein of the myocyte inner nuclear membrane, interacts with lamin A/C

17 March 2017

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Homozygous defects in LMNA, encoding lamin A/C nuclear-envelope proteins, cause autosomal recessive axonal neuropathy in human (Charcot-Marie-Tooth disorder type 2) and mouse

17 March 2017

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Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues

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Mutations in sarcomere protein genes as a cause of dilated cardiomyopathy

17 March 2017

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Identification of mutations in the gene encoding lamins A/C in autosomal dominant limb girdle muscular dystrophy with atrioventricular conduction disturbances (LGMD1B)

17 March 2017

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Nuclear lamin A/C R482Q mutation in canadian kindreds with Dunnigan-type familial partial lipodystrophy

17 March 2017

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Missense mutations in the rod domain of the lamin A/C gene as causes of dilated cardiomyopathy and conduction-system disease

17 March 2017

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Loss of A-type lamin expression compromises nuclear envelope integrity leading to muscular dystrophy

17 March 2017

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Mutations in the gene encoding lamin A/C cause autosomal dominant Emery-Dreifuss muscular dystrophy

17 March 2017

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Distribution of emerin and lamins in the heart and implications for Emery-Dreifuss muscular dystrophy

17 March 2017

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SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene

17 March 2017

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Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

17 March 2017

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Expanding the phenotype of LMNA mutations in dilated cardiomyopathy and functional consequences of these mutations.

17 March 2017

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LMNA is mutated in Hutchinson-Gilford progeria (MIM 176670) but not in Wiedemann-Rautenstrauch progeroid syndrome (MIM 264090).

29 September 2017

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Activation of Mst1 causes dilated cardiomyopathy by stimulating apoptosis without compensatory ventricular myocyte hypertrophy

29 September 2017

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Lamin a truncation in Hutchinson-Gilford progeria.

29 September 2017

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Dilated cardiomyopathy and heart failure caused by a mutation in phospholamban

29 September 2017

1 reference

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Lamins: building blocks or regulators of gene expression?

29 September 2017

1 reference

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Molecular mechanisms of inherited cardiomyopathies

29 September 2017

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Role of ANC-1 in tethering nuclei to the actin cytoskeleton.

29 September 2017

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Hearts from mice lacking desmin have a myopathy with impaired active force generation and unaltered wall compliance.

29 September 2017

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Cellular and functional defects in a mouse model of heart failure

29 September 2017

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Morphologic and biochemical hallmarks of apoptosis

29 September 2017

1 reference

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The absence of desmin leads to cardiomyocyte hypertrophy and cardiac dilation with compromised systolic function

29 September 2017

1 reference

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Regulation of peroxisome proliferator-activated receptor gamma expression by adipocyte differentiation and determination factor 1/sterol regulatory element binding protein 1: implications for adipocyte differentiation and metabolism

29 September 2017

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Structural plasticity of the cardiac nuclear pore complex in response to regulators of nuclear import

29 September 2017

1 reference

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Nuclear compartments and gene regulation.

29 September 2017

1 reference

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Nuclear lamins: their structure, assembly, and interactions

29 September 2017

1 reference

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Disruption of muscle architecture and myocardial degeneration in mice lacking desmin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=324538

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=324538

Apoptosis as a possible cause of gradual development of complete heart block and fatal arrhythmias associated with absence of the AV node, sinus node, and internodal pathways

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=324538

Nuclear matrix and the regulation of gene expression: tissue specificity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=324538

Linearity of the Frank-Starling relationship in the intact heart: the concept of preload recruitable stroke work

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=324538

The cellular basis of the length-tension relation in cardiac muscle

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=324538

Binding of two desmin derivatives to the plasma membrane and the nuclear envelope of avian erythrocytes: evidence for a conserved site-specificity in intermediate filament-membrane interactions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=324538

Lamin B constitutes an intermediate filament attachment site at the nuclear envelope

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=324538

Multiple linear regression is a useful alternative to traditional analyses of variance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=324538

Apoptosis: Mechanisms and Roles in Pathology

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=324538

Null mutation in the desmin gene gives rise to a cardiomyopathy.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=324538

Desmin in muscle formation and maintenance: knockouts and consequences

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=324538

The cellular and molecular response of cardiac myocytes to mechanical stress.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=324538

A progeroid syndrome in mice is caused by defects in A-type lamins

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=324538

Melusin, a muscle-specific integrin beta1-interacting protein, is required to prevent cardiac failure in response to chronic pressure overload

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=324538

Modifying gene expression programs by altering core promoter chromatin architecture.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=324538

Characterization of adiposity and metabolism in Lmna-deficient mice

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=324538

Nuclear envelope disorganization in fibroblasts from lipodystrophic patients with heterozygous R482Q/W mutations in the lamin A/C gene

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=324538

The R482Q lamin A/C mutation that causes lipodystrophy does not prevent nuclear targeting of lamin A in adipocytes or its interaction with emerin

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=324538

Single-beat determination of preload recruitable stroke work relationship: derivation and evaluation in conscious dogs.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=324538

LMNA, encoding lamin A/C, is mutated in partial lipodystrophy.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=324538

A functional enhancer suppresses silencing of a transgene and prevents its localization close to centrometric heterochromatin.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=324538

Apoptosis in the failing human heart

27 November 2018

1 reference

12 December 2020

Effects of lactate on the relative contribution of Ca2+ extrusion mechanisms to relaxation in guinea-pig ventricular myocytes

1 reference

12 December 2020

Changing the remodeling process in heart failure: basic mechanisms and laboratory results

1 reference

12 December 2020

Apoptosis of myofibres and satellite cells: exercise-induced damage in skeletal muscle of the mouse

1 reference

12 December 2020

Expression of lamin A mutated in the carboxyl-terminal tail generates an aberrant nuclear phenotype similar to that observed in cells from patients with Dunnigan-type partial lipodystrophy and Emery-Dreifuss muscular dystrophy

1 reference

12 December 2020

Effects of expressing lamin A mutant protein causing Emery-Dreifuss muscular dystrophy and familial partial lipodystrophy in HeLa cells

1 reference

12 December 2020

Properties of lamin A mutants found in Emery-Dreifuss muscular dystrophy, cardiomyopathy and Dunnigan-type partial lipodystrophy

1 reference

12 December 2020

Nuclear envelope defects associated with LMNA mutations cause dilated cardiomyopathy and Emery-Dreifuss muscular dystrophy

1 reference

12 December 2020

Impairment of the myocardial ultrastructure and changes of the cytoskeleton in dilated cardiomyopathy

1 reference

12 December 2020

A simple technique for postembedding ultrastructural immunogold labeling

1 reference

12 December 2020

Trans-cellular desmin-lamin B intermediate filament network in cardiac myocytes

1 reference

12 December 2020

A rapid optimized protocol for downward alkaline Southern blotting of DNA

1 reference

12 December 2020

Lamin proteins form an internal nucleoskeleton as well as a peripheral lamina in human cells

1 reference

12 December 2020

Apoptosis in myocytes in end-stage heart failure

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI19448

1 reference

2738188

10.1172/JCI200419448

1 reference

4540633

2738188

1 reference

2738188

4540633

1 reference

1 reference

1 reference