Cyclic-AMP-dependent protein kinase A regulates apoptosis by stabilizing the BH3-only protein Bim (Q28591851)

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21151042%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

Cyclic-AMP-dependent protein kinase A regulates apoptosis by stabilizing the BH3-only protein Bim (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21151042%20AND%20SRC:MED&resulttype=core&format=json

Protein kinase, cAMP dependent regulatory, type I, alpha

18 January 2020

main subject

apoptotic process

0 references

1 reference

B cell leukemia/lymphoma 2

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Holly Anderton

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21151042%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

David C Huang

7

1 reference

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18 January 2020

Andreas Strasser

9

1 reference

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18 January 2020

Hamsa Puthalakath

10

1 reference

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18 January 2020

author name string

Diane Moujalled

1

2 references

31 January 2017

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18 January 2020

Ross Weston

2

2 references

31 January 2017

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18 January 2020

Robert Ninnis

4

2 references

31 January 2017

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18 January 2020

Pranay Goel

5

2 references

31 January 2017

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18 January 2020

Andrew Coley

6

2 references

31 January 2017

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18 January 2020

Li Wu

8

2 references

31 January 2017

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18 January 2020

publication date

10 December 2010

1 reference

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18 January 2020

2 references

31 January 2017

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18 January 2020

volume

12

2 references

31 January 2017

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18 January 2020

issue

1

2 references

31 January 2017

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18 January 2020

page(s)

77-83

1 reference

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betaTrCP- and Rsk1/2-mediated degradation of BimEL inhibits apoptosis

18 January 2020

cites work

1 reference

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Gefitinib-induced killing of NSCLC cell lines expressing mutant EGFR requires BIM and can be enhanced by BH3 mimetics

17 March 2017

1 reference

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ERK1/2-dependent phosphorylation of BimEL promotes its rapid dissociation from Mcl-1 and Bcl-xL

17 March 2017

1 reference

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Evidence that Ser87 of BimEL is phosphorylated by Akt and regulates BimEL apoptotic function

17 March 2017

1 reference

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Minireview: PRKAR1A: normal and abnormal functions

17 March 2017

1 reference

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JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis

17 March 2017

1 reference

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The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

17 March 2017

1 reference

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ER stress triggers apoptosis by activating BH3-only protein Bim

17 March 2017

1 reference

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Modification of PATase by L/F-transferase generates a ClpS-dependent N-end rule substrate in Escherichia coli

7 April 2017

1 reference

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Bcl-2 family proteins: the sentinels of the mitochondrial apoptosis pathway.

29 September 2017

1 reference

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Frequent loss of expression of the pro-apoptotic protein Bim in renal cell carcinoma: evidence for contribution to apoptosis resistance.

29 September 2017

1 reference

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TLR-dependent Bim phosphorylation in macrophages is mediated by ERK and is connected to proteasomal degradation of the protein

29 September 2017

1 reference

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Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic.

29 September 2017

1 reference

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PKA-mediated phosphorylation regulates the function of activation-induced deaminase (AID) in B cells

29 September 2017

1 reference

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Genome-wide array-based CGH for mantle cell lymphoma: identification of homozygous deletions of the proapoptotic gene BIM.

29 September 2017

1 reference

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The pro-apoptotic protein Bim is a convergence point for cAMP/protein kinase A- and glucocorticoid-promoted apoptosis of lymphoid cells

29 September 2017

1 reference

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The cAMP signaling pathway as a therapeutic target in lymphoid malignancies.

29 September 2017

1 reference

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Inhibition by cAMP of Ras-dependent activation of Raf.

29 September 2017

1 reference

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Two Epstein-Barr virus (EBV) oncoproteins cooperate to repress expression of the proapoptotic tumour-suppressor Bim: clues to the pathogenesis of Burkitt's lymphoma.

3 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOR.2010.190

Bim expression is reduced in human cutaneous melanomas

21 January 2018

1 reference

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Disruption of protein kinase a regulation causes immortalization and dysregulation of D-type cyclins.

21 January 2018

1 reference

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Calpain inhibition delays neutrophil apoptosis via cyclic AMP-independent activation of protein kinase A and protein kinase A-mediated stabilization of Mcl-1 and X-linked inhibitor of apoptosis (XIAP).

21 January 2018

1 reference

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Case report of familial Carney complex due to novel frameshift mutation c.597del C (p.Phe200LeufsX6) in PRKAR1A.

21 January 2018

1 reference

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Rapid selection against truncation mutants in yeast reverse two-hybrid screens.

21 January 2018

1 reference

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Regulatory phosphorylation of Bim: sorting out the ERK from the JNK

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/21151042

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/EMBOR.2010.190

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21151042%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21151042%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

2 references