Targeted disruption of the mouse topoisomerase I gene by camptothecin selection (Q28591946)

GOA release 2020-03-11

author name string

S. G. Morham

1

1 reference

31 January 2017

K. D. Kluckman

2

1 reference

31 January 2017

N. Voulomanos

3

1 reference

31 January 2017

O. Smithies

Molecular and Cellular Biology

4

1 reference

31 January 2017

language of work or name

English

0 references

publication date

1 December 1996

1 reference

31 January 2017

1 reference

31 January 2017

16

1 reference

31 January 2017

12

1 reference

31 January 2017

6804–6809

1 reference

31 January 2017

Cloning, characterization, and sequence of the yeast DNA topoisomerase I gene

1 reference

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Function of DNA topoisomerases as replication swivels in Saccharomyces cerevisiae

17 March 2017

1 reference

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Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

17 March 2017

1 reference

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DNA topoisomerase I controls the kinetics of promoter activation and DNA topology in Saccharomyces cerevisiae

7 April 2017

1 reference

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DNA topoisomerase I is essential in Drosophila melanogaster

29 September 2017

1 reference

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Identification of human DNA topoisomerase I as a cofactor for activator-dependent transcription by RNA polymerase II.

29 September 2017

1 reference

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Mouse genes encoding DNA topoisomerase I.

29 September 2017

1 reference

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Topoisomerase I inhibitors. An overview of the camptothecin analogs.

29 September 2017

1 reference

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Recombinant fragment assay for gene targetting based on the polymerase chain reaction

29 September 2017

1 reference

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Recent studies of DNA topoisomerases

29 September 2017

1 reference

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Genetic analysis of mutations that compensate for loss of Escherichia coli DNA topoisomerase I

29 September 2017

1 reference

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DNA topoisomerases: enzymes that control DNA conformation

29 September 2017

1 reference

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cDNA cloning of human DNA topoisomerase I: catalytic activity of a 67.7-kDa carboxyl-terminal fragment

29 September 2017

1 reference

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The basis for camptothecin enhancement of DNA breakage by eukaryotic topoisomerase I.

29 September 2017

1 reference

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Molecular and genetic characterization of a radiation-induced structural rearrangement in mouse chromosome 2 causing mutations at the limb deformity and agouti loci

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231683

Embryonic stem cells lacking a functional inhibitory G-protein subunit (alpha i2) produced by gene targeting of both alleles

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231683

Camptothecin cytotoxicity in mammalian cells is associated with the induction of persistent double strand breaks in replicating DNA.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231683

Covalent and noncovalent DNA binding by mutants of vaccinia DNA topoisomerase I

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231683

Cloning of Chinese hamster DNA topoisomerase I cDNA and identification of a single point mutation responsible for camptothecin resistance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231683

Cloning of the mouse cDNA encoding DNA topoisomerase I and chromosomal location of the gene

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231683

Establishment of a CPT-11-resistant human ovarian cancer cell line.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231683

Characterisation of a human small-cell lung cancer cell line resistant to the DNA topoisomerase I-directed drug topotecan

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231683

The role of cell cycle regulation and apoptosis triggering in determining the sensitivity of leukemic cells to topoisomerase I and II inhibitors

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231683

Lambda Charon vectors (Ch32, 33, 34 and 35) adapted for DNA cloning in recombination-deficient hosts

3 June 2018

1 reference

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Isolation of type I and II DNA topoisomerase mutants from fission yeast: single and double mutants show different phenotypes in cell growth and chromatin organization

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231683

Topoisomerase I interacts with transcribed regions in Drosophila cells.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231683

Identification of cellular proteins required for simian virus 40 DNA replication

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231683

Rapid induction of c-fos transcription reveals quantitative linkage of RNA polymerase II and DNA topoisomerase I enzyme activities

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231683

Induction of in vitro differentiation of mouse embryonal carcinoma (F9) cells by inhibitors of topoisomerases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231683

Replication of the simian virus 40 chromosome with purified proteins

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231683

Detection of topoisomerase I gene point mutation in CPT-11 resistant lung cancer cell line

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231683

Topoisomerase I alteration in a camptothecin-resistant cell line derived from Chinese hamster DC3F cells in culture

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231683

Escherichia coli DNA topoisomerase I mutants have compensatory mutations in DNA gyrase genes.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231683

Structure of the human type I DNA topoisomerase gene

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231683

Escherichia coli DNA topoisomerase I mutants: Increased supercoiling is corrected by mutations near gyrase genes

27 November 2018

1 reference

12 December 2020

Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I

1 reference

12 December 2020

Camptothecin-induced in vivo topoisomerase I cleavages in the transcriptionally active tyrosine aminotransferase gene

1 reference

12 December 2020

In vitro replication of DNA containing either the SV40 or the polyoma origin

1 reference

12 December 2020

Resistance of human leukemic and normal lymphocytes to drug-induced DNA cleavage and low levels of DNA topoisomerase II

1 reference

12 December 2020

Expression of human DNA topoisomerase I in yeast cells lacking yeast DNA topoisomerase I: restoration of sensitivity of the cells to the antitumor drug camptothecin

1 reference

12 December 2020

DNA topoisomerase I--targeted chemotherapy of human colon cancer in xenografts

1 reference

12 December 2020

Identifiers

DOI

10.1128/MCB.16.12.6804

1 reference

1227072

1227072

1 reference

1 reference

1 reference