The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20 (Q28593201)

Receptor (TNFRSF)-interacting serine-threonine kinase 1

GOA release 2020-03-11

1 reference

Itchy, E3 ubiquitin protein ligase

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

4

Neal G. Copeland

1 reference

31 January 2017

5

Nancy A. Jenkins

1 reference

31 January 2017

Noula Shembade

1

1 reference

31 January 2017

Nicole S. Harhaj

2

1 reference

31 January 2017

Kislay Parvatiyar

3

1 reference

31 January 2017

Lydia E. Matesic

6

1 reference

31 January 2017

Edward W. Harhaj

Resolution phase of inflammation: novel endogenous anti-inflammatory and proresolving lipid mediators and pathways

7

1 reference

31 January 2017

language of work or name

English

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publication date

1 March 2008

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31 January 2017

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31 January 2017

9

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31 January 2017

254–262

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31 January 2017

3

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31 January 2017

1 reference

7 January 2021

NF-kappaB: linking inflammation and immunity to cancer development and progression

1 reference

7 January 2021

Chronic inflammation: a failure of resolution?

1 reference

7 January 2021

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

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7 January 2021

Signaling to NF-kappaB

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7 January 2021

NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway

1 reference

7 January 2021

Negative regulation of JNK signaling by the tumor suppressor CYLD.

1 reference

7 January 2021

Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling

1 reference

7 January 2021

Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB

1 reference

7 January 2021

The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination

1 reference

7 January 2021

CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members

1 reference

7 January 2021

NF-kappaB is essential for induction of CYLD, the negative regulator of NF-kappaB: evidence for a novel inducible autoregulatory feedback pathway

1 reference

7 January 2021

Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice

1 reference

7 January 2021

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

1 reference

7 January 2021

The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses

1 reference

7 January 2021

IkappaB kinase beta phosphorylates the K63 deubiquitinase A20 to cause feedback inhibition of the NF-kappaB pathway

1 reference

7 January 2021

Essential role for TAX1BP1 in the termination of TNF-alpha-, IL-1- and LPS-mediated NF-kappaB and JNK signaling

1 reference

7 January 2021

The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases

1 reference

7 January 2021

T6BP, a TRAF6-interacting protein involved in IL-1 signaling

1 reference

7 January 2021

T6BP and NDP52 are myosin VI binding partners with potential roles in cytokine signalling and cell adhesion

1 reference

7 January 2021

A human suppressor of c-Jun N-terminal kinase 1 activation by tumor necrosis factor alpha

1 reference

7 January 2021

Human T cell leukemia virus type I and neurologic disease: events in bone marrow, peripheral blood, and central nervous system during normal immune surveillance and neuroinflammation

1 reference

7 January 2021

Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease

1 reference

7 January 2021

IKKgamma serves as a docking subunit of the IkappaB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax protein

1 reference

7 January 2021

Role of Adapter Function in Oncoprotein-mediated Activation of NF-κB

1 reference

7 January 2021

IKKgamma mediates the interaction of cellular IkappaB kinases with the tax transforming protein of human T cell leukemia virus type 1.

1 reference

7 January 2021

Persistent activation of NF-kappaB by the tax transforming protein of HTLV-1: hijacking cellular IkappaB kinases

1 reference

7 January 2021

Mechanisms of persistent NF-kappaB activation by HTLV-I tax.

1 reference

7 January 2021

Human T-cell leukemia virus oncoprotein tax represses nuclear receptor-dependent transcription by targeting coactivator TAX1BP1.

1 reference

7 January 2021

Characterization of a novel protein-binding module--the WW domain

1 reference

7 January 2021

Dysregulation of T lymphocyte function in itchy mice: a role for Itch in TH2 differentiation.

1 reference

7 January 2021

The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover

1 reference

7 January 2021

Lethal cutaneous disease in transgenic mice conditionally expressing type I human T cell leukemia virus Tax.

1 reference

7 January 2021

ABIN-1 binds to NEMO/IKKgamma and co-operates with A20 in inhibiting NF-kappaB

1 reference

7 January 2021

LIND/ABIN-3 is a novel lipopolysaccharide-inducible inhibitor of NF-kappaB activation

1 reference

7 January 2021

The tumor necrosis factor-inducible zinc finger protein A20 interacts with TRAF1/TRAF2 and inhibits NF-kappaB activation

1 reference

7 January 2021

TRAF1 is a negative regulator of TNF signaling. enhanced TNF signaling in TRAF1-deficient mice

1 reference

7 January 2021

Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis

1 reference

7 January 2021

Retroviral oncoprotein Tax deregulates NF-kappaB by activating Tak1 and mediating the physical association of Tak1-IKK

1 reference

7 January 2021

Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO

1 reference

7 January 2021

Human T cell leukemia virus type I (HTLV-I) and human diseases

1 reference

7 January 2021

Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins

1 reference

7 January 2021

Functional dichotomy of A20 in apoptotic and necrotic cell death

1 reference

7 January 2021

NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100

1 reference

7 January 2021

Activation of NF-kappa B by the human T cell leukemia virus type I Tax oncoprotein is associated with ubiquitin-dependent relocalization of I kappa B kinase

1 reference

7 January 2021

The human T-cell leukemia virus type 1 Tax oncoprotein requires the ubiquitin-conjugating enzyme Ubc13 for NF-kappaB activation

1 reference

7 January 2021

Identifiers

DOI

10.1038/NI1563

1 reference

Consolidated OpenCitations Corpus – April 2017

4146237

4146237

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference