Modulation of p53 degradation via MDM2-mediated ubiquitylation and the ubiquitin-proteasome system during reperfusion after stroke: role of oxidative stress (Q28593530)

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English	Modulation of p53 degradation via MDM2-mediated ubiquitylation and the ubiquitin-proteasome system during reperfusion after stroke: role of oxidative stress	scientific journal article

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scholarly article

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PubMed publication ID

31 January 2017

Modulation of p53 degradation via MDM2-mediated ubiquitylation and the ubiquitin-proteasome system during reperfusion after stroke: role of oxidative stress (English)

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PubMed publication ID

31 January 2017

ubiquitin-proteasome system

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Transformation related protein 53

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GOA release 2020-03-11

Transformed mouse 3T3 cell double minute 2

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GOA release 2020-03-11

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based on heuristic

inferred from title

author name string

Atsushi Saito

1

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PubMed publication ID

31 January 2017

Takeshi Hayashi

2

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PubMed publication ID

31 January 2017

Shuzo Okuno

3

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PubMed publication ID

31 January 2017

Tatsuro Nishi

4

1 reference

PubMed publication ID

31 January 2017

Pak H. Chan

5

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PubMed publication ID

31 January 2017

publication date

1 February 2005

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PubMed publication ID

31 January 2017

Journal of Cerebral Blood Flow & Metabolism

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PubMed publication ID

31 January 2017

25

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PubMed publication ID

31 January 2017

2

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PubMed publication ID

31 January 2017

267–280

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PubMed publication ID

31 January 2017

Selective proteasomal dysfunction in the hippocampal CA1 region after transient forebrain ischemia

1 reference

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21 January 2018

Crosstalk between nitric oxide and zinc pathways to neuronal cell death involving mitochondrial dysfunction and p38-activated K+ channels

1 reference

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Phosphatidylinositol 3-kinase signaling inhibits DAF-16 DNA binding and function via 14-3-3-dependent and 14-3-3-independent pathways

1 reference

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21 January 2018

Role of oxidants in ischemic brain damage

1 reference

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21 January 2018

Reactive oxygen radicals in signaling and damage in the ischemic brain

1 reference

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Staring, a novel E3 ubiquitin-protein ligase that targets syntaxin 1 for degradation

1 reference

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21 January 2018

p53 expression in brain after middle cerebral artery occlusion in the rat

1 reference

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21 January 2018

Structure and functions of the 20S and 26S proteasomes

1 reference

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21 January 2018

Cellular survival: a play in three Akts

1 reference

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21 January 2018

Ubiquitin pathway involvement in human lymphocyte gamma-irradiation-induced apoptosis

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The proteasome, a novel protease regulated by multiple mechanisms

1 reference

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Dephosphorylation targets Bcl-2 for ubiquitin-dependent degradation: a link between the apoptosome and the proteasome pathway.

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PI3K: downstream AKTion blocks apoptosis

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21 January 2018

Mdm2 promotes the rapid degradation of p53

1 reference

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21 January 2018

Ubiquitin stress response in postischemic hippocampal neurons under nontolerant and tolerant conditions

1 reference

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21 January 2018

Critical contribution of the MDM2 acidic domain to p53 ubiquitination

1 reference

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21 January 2018

Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn superoxide dismutase

1 reference

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21 January 2018

Regulation of p53 stability by Mdm2

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21 January 2018

Carbonyl assays for determination of oxidatively modified proteins.

1 reference

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21 January 2018

p53-immunoreactive protein and p53 mRNA expression after transient middle cerebral artery occlusion in rats

1 reference

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21 January 2018

Aggravation of brain injury after transient focal ischemia in p53-deficient mice

1 reference

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21 January 2018

A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

1 reference

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21 January 2018

Hippocampal Myc and p53 expression following transient global ischemia

1 reference

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21 January 2018

Down-regulation of parkin protein in transient focal cerebral ischemia: A link between stroke and degenerative disease?

1 reference

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21 January 2018

Critical role for a central part of Mdm2 in the ubiquitylation of p53.

1 reference

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21 January 2018

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

1 reference

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21 January 2018

Evidence of phosphorylation of Akt and neuronal survival after transient focal cerebral ischemia in mice

1 reference

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21 January 2018

Copper-Zinc Superoxide Dismutase Affects Akt Activation After Transient Focal Cerebral Ischemia in Mice

1 reference

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21 January 2018

Akt enhances Mdm2-mediated ubiquitination and degradation of p53.

1 reference

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21 January 2018

Regulation of the p53 tumor suppressor protein

1 reference

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The role of the ubiquitin-proteasome pathway in apoptosis

1 reference

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21 January 2018

Interaction between XIAP and Smac/DIABLO in the mouse brain after transient focal cerebral ischemia

1 reference

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Neuroprotective role of a proline-rich Akt substrate in apoptotic neuronal cell death after stroke: relationships with nerve growth factor

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Protein ubiquitination involving an E1-E2-E3 enzyme ubiquitin thioester cascade

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The ubiquitin-proteasome pathway and pathogenesis of human diseases

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Activation of polyubiquitin gene expression during developmentally programmed cell death

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Improved method for preparation of ubiquitin-ligated lysozyme as substrate of ATP-dependent proteolysis.

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21 January 2018

Chromosomal localization and immunological analysis of a family of human 26S proteasomal ATPases

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Hybrid proteasomes. Induction by interferon-gamma and contribution to ATP-dependent proteolysis

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Increase in p53 protein expression following cortical infarction in the spontaneously hypertensive rat.

1 reference

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21 January 2018

Human copper-zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia

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Regulation of apoptosis: the ubiquitous way

1 reference

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21 January 2018

Oxygen radicals in focal cerebral ischemia

1 reference

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Copper-zinc superoxide dismutase prevents the early decrease of apurinic/apyrimidinic endonuclease and subsequent DNA fragmentation after transient focal cerebral ischemia in mice

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Proteasomes play an essential role in thymocyte apoptosis

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Copper/zinc superoxide dismutase attenuates neuronal cell death by preventing extracellular signal-regulated kinase activation after transient focal cerebral ischemia in mice

1 reference

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7 January 2021

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Overexpression of copper/zinc superoxide dismutase in transgenic mice protects against neuronal cell death after transient focal ischemia by blocking activation of the Bad cell death signaling pathway.

1 reference

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Immunoassay for the Quantification of Intracellular Multi‐Ubiquitin Chains

1 reference

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An ATP-dependent protease and ingensin, the multicatalytic proteinase, in K562 cells

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Identifiers

10.1038/SJ.JCBFM.9600028

1 reference

PubMed publication ID

31 January 2017

PubMed publication ID

1 reference

PubMed publication ID

31 January 2017

ResearchGate publication ID

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