Characterization of bovine endothelial nitric oxide synthase as a homodimer with down-regulated uncoupled NADPH oxidase activity: tetrahydrobiopterin binding kinetics and role of haem in dimerization (Q28609898)

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English	Characterization of bovine endothelial nitric oxide synthase as a homodimer with down-regulated uncoupled NADPH oxidase activity: tetrahydrobiopterin binding kinetics and role of haem in dimerization	scientific journal article

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3 February 2017

Europe PubMed Central

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3 November 2019

Characterization of bovine endothelial nitric oxide synthase as a homodimer with down-regulated uncoupled NADPH oxidase activity: tetrahydrobiopterin binding kinetics and role of haem in dimerization (English)

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3 February 2017

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3 November 2019

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Antonius Cornelis Franciscus Gorren

4

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3 November 2019

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3 November 2019

author name string

B M List

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B Klösch

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3 November 2019

C Völker

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3 November 2019

W C Sessa

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3 November 2019

W R Kukovetz

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3 November 2019

K Schmidt

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3 November 2019

B Mayer

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3 November 2019

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1 April 1997

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3 November 2019

Biochemical Journal

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3 November 2019

323 ( Pt 1)

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3 November 2019

159-165

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3 November 2019

Determination of nitric oxide synthase cofactors: heme, FAD, FMN, and tetrahydrobiopterin

1 reference

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17 March 2017

Targeting of nitric oxide synthase to endothelial cell caveolae via palmitoylation: implications for nitric oxide signaling

1 reference

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17 March 2017

Identification of covalently bound amino-terminal myristic acid in endothelial nitric oxide synthase

1 reference

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17 March 2017

Cysteine 99 of endothelial nitric oxide synthase (NOS-III) is critical for tetrahydrobiopterin-dependent NOS-III stability and activity

1 reference

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17 March 2017

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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17 March 2017

Molecular cloning and characterization of human endothelial nitric oxide synthase

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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17 March 2017

Enlarged infarcts in endothelial nitric oxide synthase knockout mice are attenuated by nitro-L-arginine

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29 September 2017

Large-scale purification of rat brain nitric oxide synthase from baculovirus overexpression system

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29 September 2017

Characterization of heme-deficient neuronal nitric-oxide synthase reveals a role for heme in subunit dimerization and binding of the amino acid substrate and tetrahydrobiopterin.

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29 September 2017

Acylation targets emdothelial nitric-oxide synthase to plasmalemmal caveolae

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Intracellular assembly of inducible NO synthase is limited by nitric oxide-mediated changes in heme insertion and availability

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29 September 2017

Characterization of bovine endothelial nitric oxide synthase expressed in E. coli.

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29 September 2017

Expression of human inducible nitric oxide synthase in a tetrahydrobiopterin (H4B)-deficient cell line: H4B promotes assembly of enzyme subunits into an active dimer

1 reference

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29 September 2017

Mutation of N-myristoylation site converts endothelial cell nitric oxide synthase from a membrane to a cytosolic protein

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29 September 2017

Nitric oxide synthase is localized predominantly in the Golgi apparatus and cytoplasmic vesicles of vascular endothelial cells

1 reference

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29 September 2017

In search of a function for tetrahydrobiopterin in the biosynthesis of nitric oxide.

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29 September 2017

Structural analysis of porcine brain nitric oxide synthase reveals a role for tetrahydrobiopterin and L-arginine in the formation of an SDS-resistant dimer.

1 reference

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29 September 2017

Nitric oxide synthases: properties and catalytic mechanism

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29 September 2017

Heme requirement for production of active endothelial nitric oxide synthase in baculovirus-infected insect cells.

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29 September 2017

Nitric oxide synthases: why so complex?

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29 September 2017

Nitric oxide synthases reveal a role for calmodulin in controlling electron transfer

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29 September 2017

Oligomerization of endothelial nitric oxide synthase. Evidence for a dominant negative effect of truncation mutants

1 reference

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Characterization of a catalytically self-sufficient 119,000-dalton cytochrome P-450 monooxygenase induced by barbiturates in Bacillus megaterium.

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Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells

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Purification and characterization of the cytokine-induced macrophage nitric oxide synthase: an FAD- and FMN-containing flavoprotein

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Purification of a soluble isoform of guanylyl cyclase-activating-factor synthase

1 reference

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29 September 2017

Molecular cloning and characterization of the constitutive bovine aortic endothelial cell nitric oxide synthase

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29 September 2017

Molecular cloning and expression of a cDNA encoding endothelial cell nitric oxide synthase

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29 September 2017

Endothelial nitric oxide synthase: molecular cloning and characterization of a distinct constitutive enzyme isoform

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29 September 2017

Overexpression of neuronal nitric oxide synthase in insect cells reveals requirement of haem for tetrahydrobiopterin binding

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3 June 2018

Endothelial nitric-oxide synthase. Expression in Escherichia coli, spectroscopic characterization, and role of tetrahydrobiopterin in dimer formation.

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3 June 2018

Endothelial nitric oxide synthase. N-terminal myristoylation determines subcellular localization

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Role of the enzyme calmodulin-binding domain in membrane association and phospholipid inhibition of endothelial nitric oxide synthase

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3 June 2018

Recombinant endothelial nitric oxide synthase: post-translational modifications in a baculovirus expression system.

1 reference

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3 June 2018

Expression of rat brain nitric oxide synthase in baculovirus-infected insect cells and characterization of the purified enzyme

1 reference

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3 June 2018

Synthesis and characterization of 3H-labelled tetrahydrobiopterin

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3 June 2018

The pteridine binding site of brain nitric oxide synthase. Tetrahydrobiopterin binding kinetics, specificity, and allosteric interaction with the substrate domain.

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Glutamate receptors induce a burst of superoxide via activation of nitric oxide synthase in arginine-depleted neurons.

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Radioligand binding to muscarinic receptors of bovine aortic endothelial cells

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3 June 2018

Brain nitric oxide synthase is a biopterin- and flavin-containing multi-functional oxido-reductase.

1 reference

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3 June 2018

Ca2+/calmodulin-dependent cytochrome c reductase activity of brain nitric oxide synthase

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3 June 2018

Ca2+/calmodulin-dependent formation of hydrogen peroxide by brain nitric oxide synthase

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3 June 2018

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3 June 2018

Generation of superoxide by purified brain nitric oxide synthase

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3 June 2018

Multiple catalytic functions of brain nitric oxide synthase. Biochemical characterization, cofactor-requirement, and the role of N omega-hydroxy-L-arginine as an intermediate.

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Effects of Cerebral Ischemia in Mice Deficient in Neuronal Nitric Oxide Synthase

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The inhibition of the constitutive bovine endothelial nitric oxide synthase by imidazole and indazole agents

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12 December 2020

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Tetrahydrobiopterin and dysfunction of endothelial nitric oxide synthase in coronary arteries

1 reference

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12 December 2020

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Kinetics and Mechanism of Tetrahydrobiopterin-induced Oxidation of Nitric Oxide

1 reference

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12 December 2020

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Molecular mechanisms of inhibition of porcine brain nitric oxide synthase by the antinociceptive drug 7-nitro-indazole

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Biosynthesis and palmitoylation of endothelial nitric oxide synthase: mutagenesis of palmitoylation sites, cysteines-15 and/or -26, argues against depalmitoylation-induced translocation of the enzyme

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Identifiers

10.1042/BJ3230159

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Europe PubMed Central

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3 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9173876%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

2 references

3 February 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9173876%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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