The metabolic activation of abacavir by human liver cytosol and expressed human alcohol dehydrogenase isozymes (Q28610405)

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900059-5

The immunologic and metabolic basis of drug hypersensitivities

7 January 2021

1 reference

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New concepts in immunology relevant to idiosyncratic drug reactions: the "danger hypothesis" and innate immune system

7 January 2021

1 reference

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The role of reactive drug metabolites in immune-mediated adverse drug reactions

7 January 2021

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Drug-protein conjugation and its immunological consequences

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900059-5

Hypersensitivity reactions during therapy with the nucleoside reverse transcriptase inhibitor abacavir

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900059-5

Role of Covalent and Noncovalent Interactions in Cell Toxicity: Effects on Proteins

7 January 2021

1 reference

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Pharmacokinetics of [(14)C]abacavir, a human immunodeficiency virus type 1 (HIV-1) reverse transcriptase inhibitor, administered in a single oral dose to HIV-1-infected adults: a mass balance study

7 January 2021

1 reference

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Drug-protein conjugates--XVI. Studies of sorbinil metabolism: formation of 2-hydroxysorbinil and unstable protein conjugates

7 January 2021

1 reference

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Structural characterisation of acetaldehyde adducts formed by a synthetic peptide mimicking the N-terminus of the hemoglobin beta-chain under reducing and nonreducing conditions

7 January 2021

1 reference

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Enhancement of acetaldehyde-protein adduct formation by l-ascorbate

7 January 2021

1 reference

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The formation and stability of imidazolidinone adducts from acetaldehyde and model peptides. A kinetic study with implications for protein modification in alcohol abuse

7 January 2021

1 reference

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Cytotoxicity of alkylating agents in isolated rat kidney proximal tubular and distal tubular cells

7 January 2021

1 reference

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Quantification in patient urine samples of felbamate and three metabolites: acid carbamate and two mercapturic acids

7 January 2021

1 reference

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Metabolism of 4-hydroxynonenal, a cytotoxic product of lipid peroxidation, in rat precision-cut liver slices

7 January 2021

1 reference

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Probability-based protein identification by searching sequence databases using mass spectrometry data

7 January 2021

1 reference

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Differences in kinetic characteristics and in sensitivity to inhibitors between human and rat liver alcohol dehydrogenase and aldehyde dehydrogenase

7 January 2021

1 reference

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Metabolism of 2,4-dinitrotoluene and 2,6-dinitrotoluene, and their dinitrobenzyl alcohols and dinitrobenzaldehydes by Wistar and Sprague-Dawley rat liver microsomal and cytosol fractions

7 January 2021

1 reference

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The role of liver alcohol dehydrogenase isoenzymes in the oxidation of glycolethers in male and female rats

7 January 2021

1 reference

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Mechanism of aldehyde oxidation catalyzed by horse liver alcohol dehydrogenase

7 January 2021

1 reference

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Aldehyde dismutase activity of human liver alcohol dehydrogenase

7 January 2021

1 reference

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Pharmacogenetics of the alcohol dehydrogenase system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900059-5

Catalytic properties of human liver alcohol dehydrogenase isoenzymes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900059-5

Oxidation of thiodiglycol (2,2'-thiobis-ethanol) by alcohol dehydrogenase: comparison of human isoenzymes

7 January 2021

1 reference

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Activities of human alcohol dehydrogenases in the metabolic pathways of ethanol and serotonin

7 January 2021

1 reference

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3 beta-Hydroxy-5 beta-steroid dehydrogenase activity of human liver alcohol dehydrogenase is specific to gamma-subunits

7 January 2021

1 reference

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Human liver class I alcohol dehydrogenaseγγ isozyme: the sole cytosolic 3β-hydroxysteroid dehydrogenase of iso bile acids

7 January 2021

1 reference

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Formation and isolation of Δ5-3-ketosteroids using a purified rat liver alcohol dehydrogenase

7 January 2021

1 reference

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Determination of hemoglobin adducts from aldehydes formed during lipid peroxidation in vitro

7 January 2021

1 reference

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An immunochemical approach of identifying and characterizing protein targets of toxic reactive metabolites

7 January 2021

1 reference

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Covalent binding of sulfamethoxazole reactive metabolites to human and rat liver subcellular fractions assessed by immunochemical detection

7 January 2021

1 reference

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The gamma 1 and gamma 2 subunits of human liver alcohol dehydrogenase. cDNA structures, two amino acid replacements, and compatibility with changes in the enzymatic properties

7 January 2021

1 reference

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