Cyclopentenone prostaglandins suppress activation of microglia: down-regulation of inducible nitric-oxide synthase by 15-deoxy-Delta12,14-prostaglandin J2 (Q28619368)

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Language	Label	Description	Also known as
English	Cyclopentenone prostaglandins suppress activation of microglia: down-regulation of inducible nitric-oxide synthase by 15-deoxy-Delta12,14-prostaglandin J2	scientific journal article

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scholarly article

1 reference

3 February 2017

Cyclopentenone prostaglandins suppress activation of microglia: down-regulation of inducible nitric-oxide synthase by 15-deoxy-Delta12,14-prostaglandin J2 (English)

1 reference

3 February 2017

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15-deoxy-Delta(12,14)-prostaglandin J2(1-)

1 reference

ChEBI release 2020-05-28

author name string

T. V. Petrova

1

1 reference

3 February 2017

K. T. Akama

2

1 reference

3 February 2017

L. J. Van Eldik

3

1 reference

3 February 2017

language of work or name

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publication date

13 April 1999

1 reference

3 February 2017

Proceedings of the National Academy of Sciences of the United States of America

1 reference

3 February 2017

96

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3 February 2017

8

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3 February 2017

4668–4673

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3 February 2017

Localization of a cyclopentenone prostaglandin to the endoplasmic reticulum and induction of BiP mRNA

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17 March 2017

CREB-binding protein/p300 are transcriptional coactivators of p65

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Inhibition of nuclear factor kappa B by prostaglandin A1: an effect associated with heat shock transcription factor activation

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17 March 2017

15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma

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7 April 2017

An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)

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PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines

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The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation

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7 April 2017

A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation

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Cytokine-mediated transcriptional induction of the human inducible nitric oxide synthase gene requires both activator protein 1 and nuclear factor kappaB-binding sites

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Amyloid beta-peptide stimulates nitric oxide production in astrocytes through an NFkappaB-dependent mechanism

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Amyloid-beta peptide activates cultured astrocytes: morphological alterations, cytokine induction and nitric oxide release.

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Fibrillar beta-amyloid induces microglial phagocytosis, expression of inducible nitric oxide synthase, and loss of a select population of neurons in the rat CNS in vivo.

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Glial-neuronal interactions in Alzheimer's disease: the potential role of a 'cytokine cycle' in disease progression

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The transcriptional activity of NF-kappaB is regulated by the IkappaB-associated PKAc subunit through a cyclic AMP-independent mechanism

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Cloning and identification of mouse steroid receptor coactivator-1 (mSRC-1), as a coactivator of peroxisome proliferator-activated receptor gamma.

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Biological actions of delta 12-prostaglandin J2.

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Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies

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Macrophage nitric oxide synthase gene: two upstream regions mediate induction by interferon gamma and lipopolysaccharide

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Identification of a cis-regulatory element for delta 12-prostaglandin J2-induced expression of the rat heme oxygenase gene

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Induction of prostanoid biosynthesis by bacterial lipopolysaccharide and isoproterenol in rat microglial cultures

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Cloning and expression of inducible nitric oxide synthase from rat astrocytes.

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Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase

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3 June 2018

9-Deoxy-delta 9, delta 12-13,14-dihydroprostaglandin D2, a metabolite of prostaglandin D2 formed in human plasma

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Regional distribution of prostaglandins D2, E2, and F2 alpha and related enzymes in postmortem human brain.

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Identification of calmodulin-binding proteins in chicken embryo fibroblasts

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Occurrence of 9-deoxy-delta 9,delta 12-13,14-dihydroprostaglandin D2 in human urine

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Relationship of microglia and astrocytes to amyloid deposits of Alzheimer disease.

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Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease

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Alzheimer's disease. A double-labeling immunohistochemical study of senile plaques

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Immortalization of murine microglial cells by a v-raf/v-myc carrying retrovirus

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Identification of prostaglandin D2 as a major prostaglandin in homogenates of rat brain

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Nitric oxide synthase in reactive astrocytes adjacent to beta-amyloid plaques.

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S100 beta stimulates inducible nitric oxide synthase activity and mRNA levels in rat cortical astrocytes.

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21 January 2018

Different intracellular locations for prostaglandin endoperoxide H synthase-1 and -2.

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Interleukin-4 induces proliferation and activation of microglia but suppresses their induction of class II major histocompatibility complex antigen expression

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of BiP gene expression by cyclopentenone prostaglandins through unfolded protein response element

1 reference

https://pubmed.ncbi.nlm.nih.gov/10200320

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inducible nitric oxide synthase expression in activated rat microglial cultures is downregulated by exogenous prostaglandin E2 and by cyclooxygenase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/10200320

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.96.8.4668

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1999PNAS...96.4668P

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release_gufb773dungjjf3l4xkhxqjn4y

1 reference

https://api.fatcat.wiki/v0/release/gufb773dungjjf3l4xkhxqjn4y

24 November 2022

based on heuristic

mapped directly with Wikidata item

0 references

1 reference

3 February 2017

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