A role for Src in signal relay by the platelet-derived growth factor alpha receptor (Q28645730)

3 February 2017

title

A role for Src in signal relay by the platelet-derived growth factor alpha receptor (English)

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3 February 2017

J. A. Gelderloos

1

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3 February 2017

S. Rosenkranz

series ordinal

2

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3 February 2017

C. Bazenet

series ordinal

3

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3 February 2017

A. Kazlauskas

series ordinal

4

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3 February 2017

language of work or name

English

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publication date

6 March 1998

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Journal of Biological Chemistry

3 February 2017

published in

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3 February 2017

volume

273

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3 February 2017

issue

10

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3 February 2017

page(s)

5908–5915

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Phosphorylation of tyrosine 720 in the platelet-derived growth factor alpha receptor is required for binding of Grb2 and SHP-2 but not for activation of Ras or cell proliferation

3 February 2017

cites work

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Receptor tyrosine kinases and their targets

21 January 2018

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Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal

21 January 2018

1 reference

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Demonstration of functionally different interactions between phospholipase C-gamma and the two types of platelet-derived growth factor receptors

21 January 2018

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Tyrosine mutations within the alpha platelet-derived growth factor receptor kinase insert domain abrogate receptor-associated phosphatidylinositol-3 kinase activity without affecting mitogenic or chemotactic signal transduction

21 January 2018

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Biological function of PDGF-induced PI-3 kinase activity: its role in alpha PDGF receptor-mediated mitogenic signaling.

21 January 2018

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Platelet-derived growth factor induces multisite phosphorylation of pp60c-src and increases its protein-tyrosine kinase activity.

21 January 2018

1 reference

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The product of the protooncogene c-src is modified during the cellular response to platelet-derived growth factor

21 January 2018

1 reference

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Association between the PDGF receptor and members of the src family of tyrosine kinases

21 January 2018

1 reference

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Sequence requirements for binding of Src family tyrosine kinases to activated growth factor receptors

21 January 2018

1 reference

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The Src family tyrosine kinases are required for platelet-derived growth factor-mediated signal transduction in NIH 3T3 cells

21 January 2018

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Myc but not Fos rescue of PDGF signalling block caused by kinase-inactive Src.

21 January 2018

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Altered phosphorylation and activation of pp60c-src during fibroblast mitosis

21 January 2018

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Mitosis-specific phosphorylation of p60c-src by p34cdc2-associated protein kinase

21 January 2018

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Purified maturation promoting factor phosphorylates pp60c-src at the sites phosphorylated during fibroblast mitosis

21 January 2018

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Requirement for Src family protein tyrosine kinases in G2 for fibroblast cell division

21 January 2018

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Src family protein tyrosine kinases and cellular signal transduction pathways

21 January 2018

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Platelet-derived growth factor-dependent activation of phosphatidylinositol 3-kinase is regulated by receptor binding of SH2-domain-containing proteins which influence Ras activity

21 January 2018

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Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

21 January 2018

1 reference

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The platelet-derived growth factor beta receptor triggers multiple cytoplasmic signaling cascades that arrive at the nucleus as distinguishable inputs

21 January 2018

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c-fos protein can induce cellular transformation: a novel mechanism of activation of a cellular oncogene.

21 January 2018

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c-myc gene expression is stimulated by agents that activate protein kinase C and does not account for the mitogenic effect of PDGF.

21 January 2018

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Role of protein kinase C in intracellular signaling

21 January 2018

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Shc proteins are phosphorylated and regulated by the v-Src and v-Fps protein-tyrosine kinases

21 January 2018

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Augmented mitogenic responsiveness to epidermal growth factor in murine fibroblasts that overexpress pp60c-src

21 January 2018

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Potentiation of epidermal growth factor receptor-mediated oncogenesis by c-Src: implications for the etiology of multiple human cancers

21 January 2018

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Src family protein tyrosine kinases: cooperating with growth factor and adhesion signaling pathways

21 January 2018

1 reference

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Phosphorylation and activation of epidermal growth factor receptors in cells transformed by the src oncogene

21 January 2018

1 reference

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Requirement for c-Src catalytic activity and the SH3 domain in platelet-derived growth factor BB and epidermal growth factor mitogenic signaling

21 January 2018

1 reference

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DNA synthesis induced by some but not all growth factors requires Src family protein tyrosine kinases.

21 January 2018

1 reference

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Platelet-derived growth factor-dependent cellular transformation requires either phospholipase Cgamma or phosphatidylinositol 3 kinase

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.273.10.5908

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