Vaccine platforms combining circumsporozoite protein and potent immune modulators, rEA or EAT-2, paradoxically result in opposing immune responses (Q28740832)

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scientific article (publication date: 2011)

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English	Vaccine platforms combining circumsporozoite protein and potent immune modulators, rEA or EAT-2, paradoxically result in opposing immune responses	scientific article (publication date: 2011)

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scholarly article

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Vaccine platforms combining circumsporozoite protein and potent immune modulators, rEA or EAT-2, paradoxically result in opposing immune responses (English)

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Youssef A. Kousa

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object named as

Youssef Kousa

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author name string

Nathaniel J Schuldt

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Yasser A Aldhamen

2

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Daniel M Appledorn

3

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Sergey S Seregin

4

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Sarah Godbehere

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Andrea Amalfitano

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language of work or name

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publication date

2011

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6

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8

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e24147

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copyright license

Creative Commons Attribution 4.0 International

30 August 2011

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April 2022 Public Data File from Crossref

copyright status

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Expression of the SLAM family of receptors adapter EAT-2 as a novel strategy for enhancing beneficial immune responses to vaccine antigens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166157

17 March 2017

The RTS,S malaria vaccine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166157

17 March 2017

A new adenovirus based vaccine vector expressing an Eimeria tenella derived TLR agonist improves cellular immune responses to an antigenic target

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166157

17 March 2017

Structure of the Plasmodium falciparum circumsporozoite protein, a leading malaria vaccine candidate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166157

17 March 2017

Efficacy of RTS,S/AS01E vaccine against malaria in children 5 to 17 months of age

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166157

17 March 2017

Protection of humans against malaria by immunization with radiation-attenuated Plasmodium falciparum sporozoites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166157

17 March 2017

Signaling lymphocytic activation molecule is expressed on CD40 ligand-activated dendritic cells and directly augments production of inflammatory cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166157

17 March 2017

A simplified system for generating recombinant adenoviruses

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166157

17 March 2017

Plasmodium circumsporozoite protein promotes the development of the liver stages of the parasite

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166157

9 May 2017

Extreme CD8 T cell requirements for anti-malarial liver-stage immunity following immunization with radiation attenuated sporozoites.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166157

3 June 2018

How do SAP family deficiencies compromise immunity?

1 reference

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3 June 2018

CD8+ T cell responses following replication-defective adenovirus serotype 5 immunization are dependent on CD11c+ dendritic cells but show redundancy in their requirement of TLR and nucleotide-binding oligomerization domain-like receptor signaling

1 reference

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3 June 2018

TRIF, and TRIF-interacting TLRs differentially modulate several adenovirus vector-induced immune responses.

1 reference

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3 June 2018

T-cell correlates of vaccine efficacy after a heterologous simian immunodeficiency virus challenge

1 reference

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3 June 2018

SLAM family receptors and the SLAM-associated protein (SAP) modulate T cell functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166157

3 June 2018

Regulation of adaptive immunity by the innate immune system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166157

3 June 2018

Randomized, double-blind, phase 2a trial of falciparum malaria vaccines RTS,S/AS01B and RTS,S/AS02A in malaria-naive adults: safety, efficacy, and immunologic associates of protection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166157

3 June 2018

Protective CD8 T cells against Plasmodium liver stages: immunobiology of an 'unnatural' immune response.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166157

3 June 2018

The X-linked lymphoproliferative syndrome gene product SAP regulates B cell function through the FcgammaRIIB receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166157

3 June 2018

Complex interactions with several arms of the complement system dictate innate and humoral immunity to adenoviral vectors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166157

3 June 2018

Sporozoite-mediated hepatocyte wounding limits Plasmodium parasite development via MyD88-mediated NF-kappa B activation and inducible NO synthase expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166157

3 June 2018

Phase I trial of an alhydrogel adjuvanted hepatitis B core virus-like particle containing epitopes of Plasmodium falciparum circumsporozoite protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166157

3 June 2018

Sterile protection against malaria is independent of immune responses to the circumsporozoite protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166157

3 June 2018

Adenovirus vector induced innate immune responses: impact upon efficacy and toxicity in gene therapy and vaccine applications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166157

3 June 2018

Priming with an adenovirus 35-circumsporozoite protein (CS) vaccine followed by RTS,S/AS01B boosting significantly improves immunogenicity to Plasmodium falciparum CS compared to that with either malaria vaccine alone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166157

3 June 2018

Adenovirus infection triggers a rapid, MyD88-regulated transcriptome response critical to acute-phase and adaptive immune responses in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166157

3 June 2018

Adenoviral infection induces a multi-faceted innate cellular immune response that is mediated by the toll-like receptor pathway in A549 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166157

3 June 2018

Toll-like receptor adaptor molecules enhance DNA-raised adaptive immune responses against influenza and tumors through activation of innate immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166157

3 June 2018

Immunogenicity and protection of a recombinant human adenovirus serotype 35-based malaria vaccine against Plasmodium yoelii in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166157

3 June 2018

Nuclear factor-kappaB: the enemy within

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166157

3 June 2018

Construction of first-generation adenoviral vectors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166157

3 June 2018

Single immunizing dose of recombinant adenovirus efficiently induces CD8+ T cell-mediated protective immunity against malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166157

3 June 2018

Safety, immunogenicity, and efficacy of a recombinantly produced Plasmodium falciparum circumsporozoite protein-hepatitis B surface antigen subunit vaccine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166157

3 June 2018

Oral Salmonella typhimurium vaccine expressing circumsporozoite protein protects against malaria.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166157

3 June 2018

Cloned cytotoxic T cells recognize an epitope in the circumsporozoite protein and protect against malaria.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166157

3 June 2018

Phase 2a trial of 0, 1, and 3 month and 0, 7, and 28 day immunization schedules of malaria vaccine RTS,S/AS02 in malaria-naïve adults at the Walter Reed Army Institute of Research

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0024147

21 January 2018

Protective immunity induced with malaria vaccine, RTS,S, is linked to Plasmodium falciparum circumsporozoite protein-specific CD4+ and CD8+ T cells producing IFN-gamma.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0024147

21 January 2018

Adenovirus 5 and 35 vectors expressing Plasmodium falciparum circumsporozoite surface protein elicit potent antigen-specific cellular IFN-gamma and antibody responses in mice.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0024147

21 January 2018

Efficient induction of protective anti-malaria immunity by recombinant adenovirus

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0024147

21 January 2018

Evaluation of a prime-boost vaccine schedule with distinct adenovirus vectors against malaria in rhesus monkeys.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0024147

21 January 2018

Wild-type adenoviruses from groups A-F evoke unique innate immune responses, of which HAd3 and SAd23 are partially complement dependent

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0024147

21 January 2018

Protective immunity against Toxoplasma challenge in mice by coadministration of T. gondii antigens and Eimeria profilin-like protein as an adjuvant

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0024147

21 January 2018

Amine reactive dyes: an effective tool to discriminate live and dead cells in polychromatic flow cytometry.

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0024147

21 January 2018

Enhanced protective immunity against malaria by vaccination with a recombinant adenovirus encoding the circumsporozoite protein of Plasmodium lacking the GPI-anchoring motif.

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0024147

21 January 2018

Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0024147

21 January 2018

Persistent Toll-like receptor signals are required for reversal of regulatory T cell-mediated CD8 tolerance

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0024147

21 January 2018

The circumsporozoite protein is an immunodominant protective antigen in irradiated sporozoites

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0024147

21 January 2018

SAP binds to CD22 and regulates B cell inhibitory signaling and calcium flux.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0024147

21 January 2018

The complexity of protective immunity against liver-stage malaria

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0024147

21 January 2018

CD8+ T-cell responses to different HIV proteins have discordant associations with viral load

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0024147

21 January 2018

Elicitation of specific cytotoxic T cells by immunization with malaria soluble synthetic polypeptides.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166157

27 November 2018

Adenovirus vector-induced innate inflammatory mediators, MAPK signaling, as well as adaptive immune responses are dependent upon both TLR2 and TLR9 in vivo

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https://pubmed.ncbi.nlm.nih.gov/21912619

12 December 2020

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Regulation of human dendritic cells by a novel specific nuclear factor-kappaB inhibitor, dehydroxymethylepoxyquinomicin

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https://pubmed.ncbi.nlm.nih.gov/21912619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1371/JOURNAL.PONE.0024147

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2011PLoSO...624147S

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