How pleiotropic genetics of the musculoskeletal system can inform genomics and phenomics of aging (Q28741685)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20596786%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

review article

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title

How pleiotropic genetics of the musculoskeletal system can inform genomics and phenomics of aging (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20596786%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

0 references

1 reference

1

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6 February 2020

author name string

David Karasik

series ordinal

1

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language of work or name

English

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publication date

2 July 2010

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6 February 2020

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6 February 2020

volume

33

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6 February 2020

page(s)

49-62

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6 February 2020

issue

1

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Genome-wide pleiotropy of osteoporosis-related phenotypes: the Framingham Study

6 February 2020

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3 June 2018

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3 June 2018

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3 June 2018

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Longevity is moderately heritable in a sample of Danish twins born 1870-1880.

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Osteocalcin: the vitamin K-dependent Ca2+-binding protein of bone matrix

3 June 2018

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3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063644

Vitamin D receptor expression in human muscle tissue decreases with age.

3 June 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

Patterns and correlates of muscle strength loss in older women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

Frailty index as a measure of biological age in a Chinese population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

The heritability of testosterone: a study of Dutch adolescent twins and their parents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

The heritability of human longevity: A population-based study of 2872 Danish twin pairs born 1870–1900

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

Heritability of body composition measured by DXA in the diabetes heart study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

Bone mineral density is a predictor of survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

The association between morbidity and radiographic hand osteoarthritis: a population-based study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

Serum osteocalcin level is associated with glucose metabolism and atherosclerosis parameters in type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

Substantial genetic effects involved in determination of circulating levels of calciotropic hormones in human pedigrees

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

Physiological factors associated with falls in older community-dwelling women

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

The Use of the Hamilton Rating Scale for Depression in Elderly Patients With Cognitive Impairment and Physical Illness

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

Further evaluation of the basic nature of the human biological aging process based on a factor analysis of age-related physiological variables

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

A method for identifying biomarkers of aging and constructing an index of biological age in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

Adverse social factors predict early ageing in middle-aged men and women: the Ebeltoft Health Study, Denmark

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

Handgrip strength and cause-specific and total mortality in older disabled women: exploring the mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

Association between estrogen receptor alpha gene variation and cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

Estrogen receptor beta polymorphisms are associated with bone mass in women and men: the Framingham Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

Heritability of body size and muscle strength in young adulthood: a study of one million Swedish men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

The androgen receptor and prostate cancer: a role for sexual selection and sexual conflict?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

Bone mineral density and the risk of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

Heritability of maximal isometric muscle strength in older female twins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

Genetics of maximal walking speed and skeletal muscle characteristics in older women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

A polymorphism in the gene for IGF-I: functional properties and risk for type 2 diabetes and myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

Body fat and skeletal muscle mass in relation to physical disability in very old men and women of the Framingham Heart Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

Skeletal muscle mass and muscle strength in relation to lower-extremity performance in older men and women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

Androgen receptor CAG repeat polymorphism is associated with fat-free mass in men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

Bone Mass and the Risk of Breast Cancer among Postmenopausal Women

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

Bone mineral density and verbal memory impairment: Third National Health and Nutrition Examination Survey.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

Bone mass and the risk of prostate cancer: The Framingham study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

Genetic Influences on Muscle Strength, Lean Body Mass, and Bone Mineral Density: A Twin Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

Differential Genetic Effects of ESR1 Gene Polymorphisms on Osteoporosis Outcomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

Heritability of reproductive hormones in adult male twins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

The genetics of exceptional human longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

Metacarpal Cortical Area and Risk of Coronary Heart Disease: The Framingham Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

Severity of Upper and Lower Extremity Functional Limitation: Scale Development and Validation With Self-Report and Performance-Based Measures of Physical Function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

Leg Muscle Mass and Composition in Relation to Lower Extremity Performance in Men and Women Aged 70 to 79: The Health, Aging and Body Composition Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

Hand grip strength: A phenotype suitable for identifying genetic variants affecting mid- and late-life physical functioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9159-3

Ability of fat and fat-free mass percentages to predict functional disability in older men and women

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063644

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063644

Effects of a short-term vitamin D and calcium supplementation on body sway and secondary hyperparathyroidism in elderly women

27 November 2018

1 reference

12 December 2020

Progression of aortic calcification is associated with metacarpal bone loss during menopause: a population-based longitudinal study

1 reference

12 December 2020

Skeletal muscle fiber quality in older men and women

1 reference

12 December 2020

Influence of insulin-like growth factor-1 and leptin on bone mass in healthy postmenopausal women

1 reference

12 December 2020

Bone loss and the progression of abdominal aortic calcification over a 25 year period: the Framingham Heart Study

1 reference

12 December 2020

The genetics of aging

1 reference

12 December 2020

Familial aggregation of 7-year changes in musculoskeletal fitness

1 reference

12 December 2020

Bone mineral density and mortality in elderly men and women: the Rotterdam Study

1 reference

12 December 2020

Skeletal muscle strength as a predictor of all-cause mortality in healthy men

1 reference

12 December 2020

Biological age--what is it and can it be measured?

1 reference

12 December 2020

Cumulative biological risk and socio-economic differences in mortality: MacArthur studies of successful aging

1 reference

12 December 2020

Determinants and upper-limit heritabilities of skeletal muscle mass and strength

1 reference

12 December 2020

Osteoarthritis in the carpometacarpal joint of the thumb. Prevalence and associations with disability and mortality

1 reference

12 December 2020

Effect of tensile force on the expression of IGF-I and IGF-I receptor in the organ-cultured rat cranial suture

1 reference

12 December 2020

Hip axis length as an independent risk factor for hip fracture independently of femural bone mineral density in Caucasian elderly Brazilian women

1 reference

12 December 2020

Using endophenotypes for pathway clusters to map complex disease genes

1 reference

12 December 2020

The contribution of epistatic pleiotropy to the genetic architecture of covariation among polygenic traits in mice

1 reference

12 December 2020

QTL With Pleiotropic Effects on Serum Levels of Bone-Specific Alkaline Phosphatase and Osteocalcin Maps to the Baboon Ortholog of Human Chromosome 6p23-21.3

1 reference

12 December 2020

Evaluation of bone metabolism and bone mass in patients with type-2 diabetes mellitus

1 reference

12 December 2020

An application of bioinformatics and text mining to the discovery of novel genes related to bone biology

1 reference

12 December 2020

Vitamin D Status Predicts Physical Performance and Its Decline in Older Persons

1 reference

12 December 2020

Functional adaptation to loading of a single bone is neuronally regulated and involves multiple bones

1 reference

12 December 2020

1 reference

12 December 2020

Factors that influence peak bone mass formation: a study of calcium balance and the inheritance of bone mass in adolescent females

1 reference

12 December 2020

Osteocalcin levels in diabetic subjects

1 reference

12 December 2020

Influence of age, sex, and insulin on osteoblast function: osteoblast dysfunction in diabetes mellitus

1 reference

12 December 2020

Do genetic factors explain associations between muscle strength, lean mass, and bone density? A twin study

1 reference

12 December 2020

Bivariate quantitative trait linkage analysis: pleiotropy versus co-incident linkages

1 reference

12 December 2020

Prospective study of dietary protein intake and risk of hip fracture in postmenopausal women

1 reference

12 December 2020

10.1007/S11357-010-9159-3

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20596786%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20596786%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

1 reference