HIV envelope gp120 activates LFA-1 on CD4 T-lymphocytes and increases cell susceptibility to LFA-1-targeting leukotoxin (LtxA) (Q28741718)

1

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Michael Tuen

2

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Gaia Vasiliver-Shamis

3

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Yelina Alvarez

4

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Kathleen C Prins

5

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Sagarika Banerjee

6

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Arthur Nádas

7

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Michael W Cho

8

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Scott C Kachlany

Creative Commons CC0 License

10

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language of work or name

English

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publication date

2011

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published in

PLOS One

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volume

6

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page(s)

e23202

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issue

8

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copyright license

start time

5 August 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

0 references

describes a project that uses

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3151267/fullTextXML

inferred from PubMed Central ID database lookup

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151267

HIV-1 envelope protein binds to and signals through integrin α4β7, the gut mucosal homing receptor for peripheral T cells

17 March 2017

1 reference

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Soluble HIV-1 gp120 enhances HIV-1 replication in non-dividing CD4+ T cells, mediated via cell signaling and Tat cofactor overexpression

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151267

HIV-1 cell to cell transfer across an Env-induced, actin-dependent synapse

17 March 2017

1 reference

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HIV envelope induces a cascade of cell signals in non-proliferating target cells that favor virus replication

17 March 2017

1 reference

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Cross-linking of T-cell surface molecules CD4 and CD8 stimulates phosphorylation of the lck tyrosine protein kinase at the autophosphorylation site

17 March 2017

1 reference

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Structural basis of integrin regulation and signaling

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1 reference

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Anti-leukemia activity of a bacterial toxin with natural specificity for LFA-1 on white blood cells

7 April 2017

1 reference

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LFA-1 antagonists as agents limiting human immunodeficiency virus type 1 infection and transmission and potentiating the effect of the fusion inhibitor T-20.

20 June 2018

1 reference

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Human immunodeficiency virus type 1 envelope gp120-induced partial T-cell receptor signaling creates an F-actin-depleted zone in the virological synapse

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Analysis of human immunodeficiency virus type 1 viremia and provirus in resting CD4+ T cells reveals a novel source of residual viremia in patients on antiretroviral therapy

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Simultaneous cell-to-cell transmission of human immunodeficiency virus to multiple targets through polysynapses

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1 reference

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Human immunodeficiency virus type 1 envelope gp120 induces a stop signal and virological synapse formation in noninfected CD4+ T cells

20 June 2018

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Antigen stimulation induces HIV envelope gp120-specific CD4(+) T cells to secrete CCR5 ligands and suppress HIV infection.

20 June 2018

1 reference

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Small GTPases and LFA-1 reciprocally modulate adhesion and signaling

20 June 2018

1 reference

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1 reference

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Organization of the integrin LFA-1 in nanoclusters regulates its activity

20 June 2018

1 reference

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R5 and X4 HIV envelopes induce distinct gene expression profiles in primary peripheral blood mononuclear cells

20 June 2018

1 reference

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20 June 2018

1 reference

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Reciprocal regulation of the nuclear factor of activated T cells and HIV-1.

20 June 2018

1 reference

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Persistent immune activation in HIV-1 infection is associated with progression to AIDS.

20 June 2018

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Polyvalent envelope glycoprotein vaccine elicits a broader neutralizing antibody response but is unable to provide sterilizing protection against heterologous Simian/human immunodeficiency virus infection in pigtailed macaques

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1 reference

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LFA-1 expression on target cells promotes human immunodeficiency virus type 1 infection and transmission

20 June 2018

1 reference

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Residual HIV-RNA levels persist for up to 2.5 years in peripheral blood mononuclear cells of patients on potent antiretroviral therapy

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1 reference

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Interaction between virion-bound host intercellular adhesion molecule-1 and the high-affinity state of lymphocyte function-associated antigen-1 on target cells renders R5 and X4 isolates of human immunodeficiency virus type 1 more refractory to neut

20 June 2018

1 reference

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20 June 2018

1 reference

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1 reference

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Progression to the G1b phase of the cell cycle is required for completion of human immunodeficiency virus type 1 reverse transcription in T cells

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1 reference

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T cells expressing activated LFA-1 are more susceptible to infection with human immunodeficiency virus type 1 particles bearing host-encoded ICAM-1

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1 reference

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Signal transduction due to HIV-1 envelope interactions with chemokine receptors CXCR4 or CCR5.

20 June 2018

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20 June 2018

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20 June 2018

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Adhesion molecule interactions facilitate human immunodeficiency virus type 1-induced virological synapse formation between T cells

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1 reference

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21 January 2018

1 reference

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21 January 2018

1 reference

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HIV envelope induces virus expression from resting CD4+ T cells isolated from HIV-infected individuals in the absence of markers of cellular activation or apoptosis

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1 reference

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21 January 2018

1 reference

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21 January 2018

1 reference

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Intermittent HIV-1 viremia (Blips) and drug resistance in patients receiving HAART.

21 January 2018

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Polymerase chain reaction-based assay for antibody-mediated neutralization of HIV-1 reveals a population of nonneutralized virus undetected by conventional p24 assay.

21 January 2018

1 reference

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Enhanced HIV type 1 neutralization by human anti-glycoprotein 120 monoclonal antibodies in the presence of monoclonal antibodies to lymphocyte function-associated molecule 1

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PubMed

https://pubmed.ncbi.nlm.nih.gov/21850260

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inferred from PubMed ID database lookup

Resolution of psoriasis by a leukocyte-targeting bacterial protein in a humanized mouse model

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PubMed

https://pubmed.ncbi.nlm.nih.gov/21850260

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inferred from PubMed ID database lookup

Purification of secreted leukotoxin (LtxA) from Actinobacillus actinomycetemcomitans

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PubMed

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Identifiers

DOI

10.1371/JOURNAL.PONE.0023202

0 references

ADS bibcode

2011PLoSO...623202H

0 references

Fatcat ID

release_ku4rudjlfvd3pnknhpvxrkyxoi

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ku4rudjlfvd3pnknhpvxrkyxoi

24 November 2022