SCFAs induce mouse neutrophil chemotaxis through the GPR43 receptor (Q28743600)

1

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G John Ferguson

2

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Suhasini Kulkarni

3

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George Damoulakis

4

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Karen Anderson

5

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Mohammad Bohlooly-Y

6

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Len Stephens

7

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Phillip T Hawkins

Creative Commons Attribution 4.0 International

8

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language of work or name

English

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publication date

2011

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published in

PLOS One

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volume

6

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page(s)

e21205

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issue

6

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copyright license

start time

15 June 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

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Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation

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Identification of a free fatty acid receptor, FFA2R, expressed on leukocytes and activated by short-chain fatty acids

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The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids

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An intracellular signaling hierarchy determines direction of migration in opposing chemotactic gradients

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Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense

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P-Rex1 regulates neutrophil function

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G protein-coupled receptor 43 is essential for neutrophil recruitment during intestinal inflammation

27 November 2018

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Short-chain fatty acids stimulate the migration of neutrophils to inflammatory sites.

27 November 2018

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PI(3)Kγ has an important context-dependent role in neutrophil chemokinesis

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Butyrate modulates intestinal epithelial cell-mediated neutrophil migration

27 November 2018

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Pertussis toxin inhibits the FMLP-induced membrane association of protein kinase C in human neutrophils

27 November 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/21698257

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Short-chain carboxylic acid concentration in human gingival crevicular fluid

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21698257

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Improved glucose control and reduced body fat mass in free fatty acid receptor 2-deficient mice fed a high-fat diet

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21698257

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0021205

1 reference

2132196

ADS bibcode

2011PLoSO...621205V

0 references

2132196

1 reference

1 reference

1 reference