The Non-Linear Child: Ontogeny, Isoniazid Concentration, and NAT2 Genotype Modulate Enzyme Reaction Kinetics and Metabolism (Q28822540)

9

object named as

William Bishai

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author name string

Zoe Rogers

1

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Hiwot Hiruy

2

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Jotam G Pasipanodya

3

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Chris Mbowane

4

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John Adamson

5

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Lihle Ngotho

6

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Farina Karim

7

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Prakash Jeena

Combined genetic and nutritional risk models of triple negative breast cancer

8

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language of work or name

English

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publication date

September 2016

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published in

EBioMedicine

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volume

11

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page(s)

118-126

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cites work

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Isoniazid pharmacokinetics, pharmacodynamics, and dosing in South African infants

20 June 2018

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Meta-analysis of clinical studies supports the pharmacokinetic variability hypothesis for acquired drug resistance and failure of antituberculosis therapy

20 June 2018

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Accuracy of various human NAT2 SNP genotyping panels to infer rapid, intermediate and slow acetylator phenotypes

20 June 2018

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Fractal geometry and the pharmacometrics of micafungin in overweight, obese, and extremely obese people

20 June 2018

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An oracle: antituberculosis pharmacokinetics-pharmacodynamics, clinical correlation, and clinical trial simulations to predict the future

20 June 2018

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Comparison of multivariate adaptive regression splines and logistic regression in detecting SNP-SNP interactions and their application in prostate cancer.

20 June 2018

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20 June 2018

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Should we use N-acetyltransferase type 2 genotyping to personalize isoniazid doses?

20 June 2018

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Developmental pharmacology--drug disposition, action, and therapy in infants and children

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Molecular mechanism of slow acetylation of drugs and carcinogens in humans

20 June 2018

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In silico children and the glass mouse model: clinical trial simulations to identify and individualize optimal isoniazid doses in children with tuberculosis

20 June 2018

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Isoniazid pharmacokinetics in children according to acetylator phenotype

26 November 2018

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Functional characterization of human N-acetyltransferase 2 (NAT2) single nucleotide polymorphisms

26 November 2018

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26 November 2018

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26 November 2018

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N-acetyltransferase polymorphism. Comparison of phenotype and genotype in humans

26 November 2018

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Differences in N-acetylation genotypes between Caucasians and Black South Africans: implications for cancer prevention

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Fatal cardiovascular collapse of infants receiving large amounts of chloramphenicol

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Arylamine N-acetyltransferase (NAT2) genotypes in Africans: the identification of a new allele with nucleotide changes 481C>T and 590G>A

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The mechanism of isoniazid acetylation by human N-acetyltransferase

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A computationally efficient approach for the design of population pharmacokinetic studies

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