Multiscale simulations reveal key features of the proton-pumping mechanism in cytochrome c oxidase (Q28830505)

4

object named as

Mårten Wikström

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author name string

Ruibin Liang

1

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Jessica M J Swanson

2

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Yuxing Peng

Proceedings of the National Academy of Sciences of the United States of America

3

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language of work or name

English

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publication date

5 July 2016

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published in

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volume

113

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issue

27

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page(s)

7420-5

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cites work

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The X-ray crystal structures of wild-type and EQ(I-286) mutant cytochrome c oxidases from Rhodobacter sphaeroides

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Microscopic basis for kinetic gating in Cytochrome c oxidase: insights from QM/MM analysis

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Hydrated Excess Protons Can Create Their Own Water Wires

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Characterizing the proton loading site in cytochrome c oxidase

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Multiscale simulation reveals a multifaceted mechanism of proton permeation through the influenza A M2 proton channel

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Changing hydration level in an internal cavity modulates the proton affinity of a key glutamate in cytochrome c oxidase

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Insights into the mechanism of proton transport in cytochrome c oxidase

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Proton-transport mechanisms in cytochrome c oxidase revealed by studies of kinetic isotope effects

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Proton-coupled electron transfer in cytochrome oxidase.

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Quantum Chemical Studies of Proton-Coupled Electron Transfer in Metalloenzymes

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Kinetic gating of the proton pump in cytochrome c oxidase

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Properties of Arg481 mutants of the aa3-type cytochrome c oxidase from Rhodobacter sphaeroides suggest that neither R481 nor the nearby D-propionate of heme a3 is likely to be the proton loading site of the proton pump

3 June 2018

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Cytochrome c oxidase: exciting progress and remaining mysteries

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The proton donor for O-O bond scission by cytochrome c oxidase

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Replacing Asn207 by aspartate at the neck of the D channel in the aa3-type cytochrome c oxidase from Rhodobacter sphaeroides results in decoupling the proton pump

3 June 2018

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Escaping free-energy minima

3 June 2018

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The role of the D- and K-pathways of proton transfer in the function of the haem-copper oxidases.

3 June 2018

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The roles of the two proton input channels in cytochrome c oxidase from Rhodobacter sphaeroides probed by the effects of site-directed mutations on time-resolved electrogenic intraprotein proton transfer

3 June 2018

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A mechanistic principle for proton pumping by cytochrome c oxidase

3 June 2018

1 reference

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Water-gated mechanism of proton translocation by cytochrome c oxidase

21 January 2018

1 reference

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Microscopic pKa analysis of Glu286 in cytochrome c oxidase (Rhodobacter sphaeroides): toward a calibrated molecular model

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1601982113

Functional hydration and conformational gating of proton uptake in cytochrome c oxidase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1601982113

Role of subunit III and its lipids in the molecular mechanism of cytochrome c oxidase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1601982113

Mechanism of Oxygen Reduction in Cytochrome c Oxidase and the Role of the Active Site Tyrosine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1601982113

Bound water in the proton translocation mechanism of the haem-copper oxidases

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1601982113

Dynamics of the glutamic acid 242 side chain in cytochrome c oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1601982113

Deuterium isotope effect of proton pumping in cytochrome c oxidase

21 January 2018

1 reference

12 December 2020

Formation of the "peroxy" intermediate in cytochrome c oxidase is associated with internal proton/hydrogen transfer

1 reference

12 December 2020

Charge transfer in the K proton pathway linked to electron transfer to the catalytic site in cytochrome c oxidase

1 reference

12 December 2020

Molecular basis of proton uptake in single and double mutants of cytochrome c oxidase

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12 December 2020

Heme/Copper Terminal Oxidases

1 reference

12 December 2020

release_pqmjc4dk35emldb44zfqzpvney

Identifiers

DOI

10.1073/PNAS.1601982113

0 references

ADS bibcode

2016PNAS..113.7420L

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Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/pqmjc4dk35emldb44zfqzpvney

24 November 2022