Norepinephrine and its metabolites are involved in the synthesis of neuromelanin derived from the locus coeruleus (Q28831116)

Shosuke Ito

6

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Kazumasa Wakamatsu

Kazumasa Wakamatsu

1

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Keisuke Tabuchi

2

Keisuke Tabuchi

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Makoto Ojika

3

Makoto Ojika

0 references

Luigi Zecca

5

Journal of Neurochemistry

Luigi Zecca

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language of work or name

English

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publication date

November 2015

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published in

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volume

135

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issue

4

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page(s)

768-76

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cites work

Spontaneous redox reactions of dopaquinone and the balance between the eumelanic and phaeomelanic pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5014224

MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degeneration

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5014224

Protective and toxic roles of dopamine in Parkinson's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5014224

Melanins and melanogenesis: methods, standards, protocols

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5014224

Neuromelanins of human brain have soluble and insoluble components with dolichols attached to the melanic structure

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5014224

Oxidation chemistry of catecholamines and neuronal degeneration: an update

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5014224

New melanic pigments in the human brain that accumulate in aging and block environmental toxic metals

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5014224

Chemistry of mixed melanogenesis--pivotal roles of dopaquinone

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5014224

Neuronal pigmented autophagic vacuoles: lipofuscin, neuromelanin, and ceroid as macroautophagic responses during aging and disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5014224

A proposed dual role of neuromelanin in the pathogenesis of Parkinson's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5014224

The role of iron and copper molecules in the neuronal vulnerability of locus coeruleus and substantia nigra during aging

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5014224

Neuromelanin of the substantia nigra: a neuronal black hole with protective and toxic characteristics

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5014224

Quantitative analysis of eumelanin and pheomelanin in humans, mice, and other animals: a comparative review

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5014224

Neuromelanin biosynthesis is driven by excess cytosolic catecholamines not accumulated by synaptic vesicles.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5014224

Oxidative metabolites of 5-S-cysteinylnorepinephrine are irreversible inhibitors of mitochondrial complex I and the alpha-ketoglutarate dehydrogenase and pyruvate dehydrogenase complexes: possible implications for neurodegenerative brain disorders

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5014224

The role of the locus coeruleus in the development of Parkinson's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5014224

Neuromelanin and Parkinson's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5014224

Lipoprotein pigments--their relationship to ageing in the human nervous system. II. The melanin content of pigmented nerve cells.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5014224

Microanalysis of eumelanin and pheomelanin in hair and melanomas by chemical degradation and liquid chromatography.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5014224

Protein-bound 3,4-dihydroxyphenylalanine is a major reductant formed during hydroxyl radical damage to proteins.

20 June 2018

1 reference

Isomeric cysteinyldopas provide a (photo)degradable bulk component and a robust structural element in red human hair pheomelanin

21 January 2018

1 reference

Oxidation chemistry of norepinephrine: partitioning of the O-quinone between competing cyclization and chain breakdown pathways and their roles in melanin formation

21 January 2018

1 reference

Serum levels of pigmentation markers are elevated in patients undergoing hemodialysis

21 January 2018

1 reference

The neuropathologic basis of different clinical subgroups of Parkinson's disease.

21 January 2018

1 reference

Correspondence of melanin-pigmented neurons in human brain with A1-A14 catecholamine cell groups.

21 January 2018

1 reference

The possible role of one-electron reduction of aminochrome in the neurodegenerative process of the dopaminergic system.

21 January 2018

1 reference

Peroxynitrite induced formation of the neurotoxins 5-S-cysteinyl-dopamine and DHBT-1: implications for Parkinson's disease and protection by polyphenols

21 January 2018

1 reference

The usefulness of 4-amino-3-hydroxyphenylalanine as a specific marker of pheomelanin

21 January 2018

1 reference

The structure of neuromelanin as studied by chemical degradative methods

21 January 2018

1 reference

Reduction of the nitro group to amine by hydroiodic acid to synthesize o-aminophenol derivatives as putative degradative markers of neuromelanin.

21 January 2018

1 reference

Neuronal loss is greater in the locus coeruleus than nucleus basalis and substantia nigra in Alzheimer and Parkinson diseases

21 January 2018

1 reference

Possible role of neuromelanin in the pathogenesis of Parkinson's disease

21 January 2018

1 reference

12 December 2020

1 reference

12 December 2020

Usefulness of alkaline hydrogen peroxide oxidation to analyze eumelanin and pheomelanin in various tissue samples: application to chemical analysis of human hair melanins

1 reference

12 December 2020

The absolute concentration of nigral neuromelanin, assayed by a new sensitive method, increases throughout the life and is dramatically decreased in Parkinson's disease

1 reference

12 December 2020

1 reference

12 December 2020

Detection of 5-S-cysteinyldopamine in human brain

1 reference

12 December 2020

Optimization of conditions for preparing synthetic pheomelanin

1 reference

12 December 2020

Improved HPLC determination of 5-S-cysteinyldopa in serum

1 reference

12 December 2020

A brainstem atlas of catecholaminergic neurons in man, using melanin as a natural marker

1 reference

12 December 2020

Biosynthetic pathway to neuromelanin and its aging process

1 reference

12 December 2020